SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fsd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3fsd NTF2-LIKE PROTEIN OF
UNKNOWN FUNCTION IN
NUTRIENT UPTAKE
(Rhodospirillum
rubrum) 		5 / 12 PHE A 109
GLY A 127
TYR A  61
LEU A  71
LEU A  22
 UNL  A 134 ( 4.8A)
None
None
None
None
 1.10A 1fm6X-3fsdA:
undetectable		 1fm6X-3fsdA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3fsd NTF2-LIKE PROTEIN OF
UNKNOWN FUNCTION IN
NUTRIENT UPTAKE
(Rhodospirillum
rubrum) 		3 / 3 ARG A  21
ILE A  15
TRP A 113
 None
 1.04A 3nw2A-3fsdA:
undetectable		 3nw2A-3fsdA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 3fsd NTF2-LIKE PROTEIN OF
UNKNOWN FUNCTION IN
NUTRIENT UPTAKE
(Rhodospirillum
rubrum) 		3 / 3 LEU A  38
LEU A  22
ARG A 111
 None
 0.57A 6fgcA-3fsdA:
undetectable		 6fgcA-3fsdA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 3fsd NTF2-LIKE PROTEIN OF
UNKNOWN FUNCTION IN
NUTRIENT UPTAKE
(Rhodospirillum
rubrum) 		3 / 3 LEU A  38
LEU A  22
ARG A 111
 None
 0.60A 6fgdA-3fsdA:
undetectable		 6fgdA-3fsdA:
17.35