SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fse'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3fse TWO-DOMAIN PROTEIN
CONTAINING
DJ-1/THIJ/PFPI-LIKE
AND FERRITIN-LIKE
DOMAINS
(Trichormus
variabilis) 		4 / 6 SER A 205
THR A 317
PHE A 325
GLY A 213
 None
 1.12A 1icuC-3fseA:
undetectable
1icuD-3fseA:
undetectable		 1icuC-3fseA:
20.91
1icuD-3fseA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3fse TWO-DOMAIN PROTEIN
CONTAINING
DJ-1/THIJ/PFPI-LIKE
AND FERRITIN-LIKE
DOMAINS
(Trichormus
variabilis) 		5 / 12 GLY A 220
LEU A 258
HIS A 254
ILE A 328
LEU A 332
 None
 1.23A 1kyvA-3fseA:
4.5
1kyvE-3fseA:
4.4		 1kyvA-3fseA:
21.10
1kyvE-3fseA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3fse TWO-DOMAIN PROTEIN
CONTAINING
DJ-1/THIJ/PFPI-LIKE
AND FERRITIN-LIKE
DOMAINS
(Trichormus
variabilis) 		5 / 12 LEU A 332
GLY A 220
LEU A 258
HIS A 254
ILE A 328
 None
 1.23A 1kyvB-3fseA:
4.6
1kyvC-3fseA:
undetectable		 1kyvB-3fseA:
21.10
1kyvC-3fseA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3fse TWO-DOMAIN PROTEIN
CONTAINING
DJ-1/THIJ/PFPI-LIKE
AND FERRITIN-LIKE
DOMAINS
(Trichormus
variabilis) 		5 / 12 LEU A 332
GLY A 220
LEU A 258
HIS A 254
ILE A 328
 None
 1.26A 1kyvC-3fseA:
undetectable
1kyvD-3fseA:
4.6		 1kyvC-3fseA:
21.10
1kyvD-3fseA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 3fse TWO-DOMAIN PROTEIN
CONTAINING
DJ-1/THIJ/PFPI-LIKE
AND FERRITIN-LIKE
DOMAINS
(Trichormus
variabilis) 		5 / 10 PHE A  73
LEU A 173
LEU A  32
ALA A  35
VAL A  39
 None
 0.66A 2bxeA-3fseA:
2.9		 2bxeA-3fseA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_A_ADNA1501_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3fse TWO-DOMAIN PROTEIN
CONTAINING
DJ-1/THIJ/PFPI-LIKE
AND FERRITIN-LIKE
DOMAINS
(Trichormus
variabilis) 		4 / 7 ARG A 264
GLU A 259
ASN A 215
PRO A 269
 None
 1.16A 2ejgA-3fseA:
undetectable		 2ejgA-3fseA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 3fse TWO-DOMAIN PROTEIN
CONTAINING
DJ-1/THIJ/PFPI-LIKE
AND FERRITIN-LIKE
DOMAINS
(Trichormus
variabilis) 		5 / 9 ALA A 128
GLY A 125
GLY A 142
ILE A 118
LEU A 117
 None
 0.96A 2z0yB-3fseA:
2.8		 2z0yB-3fseA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 3fse TWO-DOMAIN PROTEIN
CONTAINING
DJ-1/THIJ/PFPI-LIKE
AND FERRITIN-LIKE
DOMAINS
(Trichormus
variabilis) 		5 / 12 GLU A  24
PHE A 168
GLY A 113
GLY A 130
GLY A  80
 CSX  A 111 ( 3.0A)
None
CSX  A 111 ( 4.5A)
CSX  A 111 ( 3.5A)
CSX  A 111 ( 3.6A)
 1.08A 3tegA-3fseA:
undetectable		 3tegA-3fseA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 3fse TWO-DOMAIN PROTEIN
CONTAINING
DJ-1/THIJ/PFPI-LIKE
AND FERRITIN-LIKE
DOMAINS
(Trichormus
variabilis) 		4 / 6 TYR A 145
GLY A 130
VAL A 151
THR A 158
 None
CSX  A 111 ( 3.5A)
None
None
 0.97A 3tj7A-3fseA:
undetectable
3tj7B-3fseA:
undetectable		 3tj7A-3fseA:
20.06
3tj7B-3fseA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 3fse TWO-DOMAIN PROTEIN
CONTAINING
DJ-1/THIJ/PFPI-LIKE
AND FERRITIN-LIKE
DOMAINS
(Trichormus
variabilis) 		4 / 6 TYR A 145
GLY A 130
VAL A 151
THR A 158
 None
CSX  A 111 ( 3.5A)
None
None
 0.96A 3tj7C-3fseA:
undetectable
3tj7D-3fseA:
undetectable		 3tj7C-3fseA:
20.06
3tj7D-3fseA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 3fse TWO-DOMAIN PROTEIN
CONTAINING
DJ-1/THIJ/PFPI-LIKE
AND FERRITIN-LIKE
DOMAINS
(Trichormus
variabilis) 		4 / 6 VAL A 151
THR A 158
TYR A 145
GLY A 130
 None
None
None
CSX  A 111 ( 3.5A)
 0.99A 3tj7C-3fseA:
undetectable
3tj7D-3fseA:
undetectable		 3tj7C-3fseA:
20.06
3tj7D-3fseA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 3fse TWO-DOMAIN PROTEIN
CONTAINING
DJ-1/THIJ/PFPI-LIKE
AND FERRITIN-LIKE
DOMAINS
(Trichormus
variabilis) 		4 / 8 ILE A 172
ALA A 108
VAL A  12
VAL A  41
 None
 0.83A 4jltA-3fseA:
undetectable		 4jltA-3fseA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 3fse TWO-DOMAIN PROTEIN
CONTAINING
DJ-1/THIJ/PFPI-LIKE
AND FERRITIN-LIKE
DOMAINS
(Trichormus
variabilis) 		4 / 7 GLN A  34
LEU A 173
THR A 170
THR A 169
 None
 0.81A 5m78A-3fseA:
undetectable		 5m78A-3fseA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3fse TWO-DOMAIN PROTEIN
CONTAINING
DJ-1/THIJ/PFPI-LIKE
AND FERRITIN-LIKE
DOMAINS
(Trichormus
variabilis) 		5 / 9 GLY A  31
LEU A  42
ILE A 172
LEU A 176
PHE A  96
 None
 0.75A 5vkqC-3fseA:
3.7
5vkqD-3fseA:
3.7		 5vkqC-3fseA:
12.00
5vkqD-3fseA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZOV_B_ASCB501_0
(PTS
ASCORBATE-SPECIFIC
SUBUNIT IIBC)		 3fse TWO-DOMAIN PROTEIN
CONTAINING
DJ-1/THIJ/PFPI-LIKE
AND FERRITIN-LIKE
DOMAINS
(Trichormus
variabilis) 		5 / 12 PRO A  84
ILE A 134
GLN A 115
ALA A 128
ILE A  78
 None
CSX  A 111 ( 4.9A)
None
None
None
 1.40A 5zovB-3fseA:
undetectable		 5zovB-3fseA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3fse TWO-DOMAIN PROTEIN
CONTAINING
DJ-1/THIJ/PFPI-LIKE
AND FERRITIN-LIKE
DOMAINS
(Trichormus
variabilis) 		4 / 5 LEU A 332
TYR A 329
ILE A 210
GLY A 307
 None
 1.04A 6hd6A-3fseA:
undetectable		 6hd6A-3fseA:
13.08