SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fss'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 7 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.88A 1v55A-3fssA:
undetectable
1v55J-3fssA:
undetectable
1v55A-3fssA:
19.04
1v55J-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 8 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.89A 1v55N-3fssA:
undetectable
1v55W-3fssA:
undetectable
1v55N-3fssA:
19.04
1v55W-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 8 ASP A 255
SER A 254
TYR A 297
HIS A 239
None
None
None
MLA  A 302 ( 3.5A)
1.18A 2bteA-3fssA:
undetectable
2bteA-3fssA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 8 ASP A 255
SER A 254
TYR A 297
HIS A 239
None
None
None
MLA  A 302 ( 3.5A)
1.22A 2bteD-3fssA:
undetectable
2bteD-3fssA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 8 ILE A 116
SER A 115
SER A  96
LEU A 119
None
0.86A 2cdqA-3fssA:
undetectable
2cdqA-3fssA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 7 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.93A 2dyrN-3fssA:
undetectable
2dyrW-3fssA:
undetectable
2dyrN-3fssA:
19.04
2dyrW-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 8 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.89A 2eijN-3fssA:
undetectable
2eijW-3fssA:
undetectable
2eijN-3fssA:
19.04
2eijW-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 8 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.91A 2eikN-3fssA:
undetectable
2eikW-3fssA:
undetectable
2eikN-3fssA:
19.04
2eikW-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 8 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.90A 2eilN-3fssA:
undetectable
2eilW-3fssA:
undetectable
2eilN-3fssA:
19.04
2eilW-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 8 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.89A 2einA-3fssA:
undetectable
2einJ-3fssA:
undetectable
2einA-3fssA:
19.04
2einJ-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 6 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.92A 2einN-3fssA:
undetectable
2einW-3fssA:
undetectable
2einN-3fssA:
19.04
2einW-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
3 / 3 ASN A 120
ILE A 200
MET A 142
None
0.76A 2h42C-3fssA:
undetectable
2h42C-3fssA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 8 ASP A 255
SER A 254
TYR A 297
HIS A 239
None
None
None
MLA  A 302 ( 3.5A)
1.28A 2v0gA-3fssA:
undetectable
2v0gA-3fssA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XPW_A_OTCA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
5 / 12 LEU A 236
SER A 201
ASN A 202
PHE A 204
ILE A 138
MLA  A 302 (-3.9A)
MLA  A 302 (-2.6A)
None
None
None
1.10A 2xpwA-3fssA:
undetectable
2xpwA-3fssA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 8 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.93A 3abkA-3fssA:
undetectable
3abkJ-3fssA:
undetectable
3abkA-3fssA:
19.04
3abkJ-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 7 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.96A 3ablA-3fssA:
undetectable
3ablJ-3fssA:
undetectable
3ablA-3fssA:
19.04
3ablJ-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 8 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.92A 3ablN-3fssA:
undetectable
3ablW-3fssA:
undetectable
3ablN-3fssA:
19.04
3ablW-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 8 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.91A 3abmN-3fssA:
undetectable
3abmW-3fssA:
undetectable
3abmN-3fssA:
19.04
3abmW-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 6 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.97A 3ag1N-3fssA:
undetectable
3ag1W-3fssA:
undetectable
3ag1N-3fssA:
19.04
3ag1W-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 7 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.92A 3ag3A-3fssA:
undetectable
3ag3J-3fssA:
undetectable
3ag3A-3fssA:
19.04
3ag3J-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 8 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.90A 3ag3N-3fssA:
undetectable
3ag3W-3fssA:
undetectable
3ag3N-3fssA:
19.04
3ag3W-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 8 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.92A 3asnN-3fssA:
undetectable
3asnW-3fssA:
undetectable
3asnN-3fssA:
19.04
3asnW-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 8 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.91A 3asoN-3fssA:
undetectable
3asoW-3fssA:
undetectable
3asoN-3fssA:
19.04
3asoW-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 6 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.92A 3wg7N-3fssA:
undetectable
3wg7W-3fssA:
undetectable
3wg7N-3fssA:
19.04
3wg7W-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_F_ZPCF1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
5 / 12 GLU A 148
TYR A  94
TYR A 117
MET A 142
ILE A 123
None
None
None
None
GOL  A   1 (-4.4A)
1.22A 4a97F-3fssA:
0.0
4a97J-3fssA:
0.0
4a97F-3fssA:
21.36
4a97J-3fssA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_G_ZPCG1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
5 / 12 TYR A 117
MET A 142
ILE A 123
GLU A 148
TYR A  94
None
None
GOL  A   1 (-4.4A)
None
None
1.23A 4a97F-3fssA:
0.0
4a97G-3fssA:
0.0
4a97F-3fssA:
21.36
4a97G-3fssA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 8 SER A 146
ASN A 150
GLU A 148
ASN A 122
None
1.01A 4d33A-3fssA:
undetectable
4d33A-3fssA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 7 SER A 146
ASN A 150
GLU A 148
ASN A 122
None
1.04A 4d33B-3fssA:
undetectable
4d33B-3fssA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 7 SER A 146
ASN A 150
GLU A 148
ASN A 122
None
0.98A 4d39B-3fssA:
undetectable
4d39B-3fssA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
5 / 12 ILE A 241
LEU A 250
ALA A 126
SER A 127
LEU A 129
None
None
GOL  A   1 (-4.3A)
MLA  A 302 ( 4.5A)
None
1.05A 4m11B-3fssA:
undetectable
4m11B-3fssA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 7 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.94A 5b1aA-3fssA:
undetectable
5b1aJ-3fssA:
undetectable
5b1aA-3fssA:
19.04
5b1aJ-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 7 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.93A 5b1bA-3fssA:
undetectable
5b1bJ-3fssA:
undetectable
5b1bA-3fssA:
19.04
5b1bJ-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 7 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.92A 5b1bN-3fssA:
undetectable
5b1bW-3fssA:
undetectable
5b1bN-3fssA:
19.04
5b1bW-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 7 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.96A 5b3sA-3fssA:
undetectable
5b3sJ-3fssA:
undetectable
5b3sA-3fssA:
19.04
5b3sJ-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
5 / 12 LEU A 174
PHE A 169
LEU A 140
PHE A  93
LEU A 119
None
1.20A 5iepA-3fssA:
undetectable
5iepA-3fssA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
5 / 12 PHE A 169
LEU A 140
PHE A  93
ALA A 193
LEU A 119
None
1.08A 5iepA-3fssA:
undetectable
5iepA-3fssA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 7 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.92A 5iy5A-3fssA:
undetectable
5iy5J-3fssA:
undetectable
5iy5A-3fssA:
19.04
5iy5J-3fssA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJD_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
5 / 9 LEU A 114
LEU A 107
ILE A 104
LEU A 160
MET A 158
None
1.39A 5ljdA-3fssA:
undetectable
5ljdA-3fssA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
5 / 12 LEU A  91
LEU A  76
GLY A  78
LEU A 140
MET A 142
None
1.13A 5uc1A-3fssA:
undetectable
5uc1A-3fssA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
5 / 12 LEU A  91
LEU A  76
GLY A  78
LEU A 140
MET A 142
None
1.15A 5uc1B-3fssA:
undetectable
5uc1B-3fssA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 7 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.95A 5xdxA-3fssA:
undetectable
5xdxJ-3fssA:
undetectable
5xdxA-3fssA:
19.04
5xdxJ-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 6 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.95A 5z86N-3fssA:
undetectable
5z86W-3fssA:
undetectable
5z86N-3fssA:
19.04
5z86W-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 6 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.95A 5zcoN-3fssA:
undetectable
5zcoW-3fssA:
undetectable
5zcoN-3fssA:
19.04
5zcoW-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 7 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.95A 5zcpA-3fssA:
undetectable
5zcpJ-3fssA:
undetectable
5zcpA-3fssA:
19.04
5zcpJ-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 7 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.94A 5zcqA-3fssA:
undetectable
5zcqJ-3fssA:
undetectable
5zcqA-3fssA:
19.04
5zcqJ-3fssA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae)
4 / 8 ILE A 200
MET A 158
THR A 159
LEU A 160
None
0.94A 5zcqN-3fssA:
undetectable
5zcqW-3fssA:
undetectable
5zcqN-3fssA:
19.04
5zcqW-3fssA:
13.92