SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ftp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_B_ID2B2_0
(THYMIDINE KINASE)		 3ftp 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Burkholderia
pseudomallei) 		5 / 12 GLU A  81
ILE A  35
ILE A  11
ALA A  84
ARG A  59
 None
 1.46A 1ki7B-3ftpA:
2.2		 1ki7B-3ftpA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 3ftp 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Burkholderia
pseudomallei) 		4 / 5 ALA A  15
ALA A  28
ALA A  32
VAL A  87
 None
 0.86A 2nyrB-3ftpA:
4.3		 2nyrB-3ftpA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3ftp 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Burkholderia
pseudomallei) 		5 / 12 ILE A  23
ALA A  22
GLY A  18
ILE A 220
GLY A  14
 None
 0.86A 2qe6A-3ftpA:
6.0		 2qe6A-3ftpA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3ftp 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Burkholderia
pseudomallei) 		5 / 12 ILE A  23
ALA A  22
GLY A  18
ILE A 220
GLY A  14
 None
 0.88A 2qe6B-3ftpA:
5.9		 2qe6B-3ftpA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3ftp 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Burkholderia
pseudomallei) 		5 / 12 GLY A  58
GLY A  60
ALA A  24
ALA A  28
ARG A  29
 None
 1.00A 2yqzA-3ftpA:
6.3		 2yqzA-3ftpA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_A_SAMA501_0
(SPERMIDINE SYNTHASE)		 3ftp 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Burkholderia
pseudomallei) 		5 / 12 GLN A 208
TYR A 156
GLY A 187
ILE A 209
GLY A 215
 None
 1.03A 3bwcA-3ftpA:
5.8		 3bwcA-3ftpA:
26.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_A_SAMA501_0
(SPERMIDINE SYNTHASE)		 3ftp 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Burkholderia
pseudomallei) 		5 / 12 GLN A 208
TYR A 156
ILE A 189
GLY A 187
GLY A 215
 None
 0.94A 3bwcA-3ftpA:
5.8		 3bwcA-3ftpA:
26.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3ftp 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Burkholderia
pseudomallei) 		4 / 8 SER A 123
LEU A 170
THR A 142
GLY A 237
 None
 0.68A 3dcjB-3ftpA:
5.2		 3dcjB-3ftpA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA802_1
(CATALASE-PEROXIDASE)		 3ftp 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Burkholderia
pseudomallei) 		4 / 8 ILE A 209
ASN A 243
GLY A 187
ILE A 189
 None
 0.91A 3wxoA-3ftpA:
undetectable		 3wxoA-3ftpA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 3ftp 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Burkholderia
pseudomallei) 		5 / 11 ILE A  23
ILE A  19
GLY A  18
VAL A 242
GLY A 215
 None
 0.97A 4ac9B-3ftpA:
6.8
4ac9C-3ftpA:
6.4		 4ac9B-3ftpA:
20.75
4ac9C-3ftpA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 3ftp 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Burkholderia
pseudomallei) 		4 / 6 ALA A 161
ALA A 185
PRO A 186
THR A 142
 None
 1.00A 4dtzA-3ftpA:
undetectable		 4dtzA-3ftpA:
18.70