SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ftt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3ftt PUTATIVE
ACETYLTRANSFERASE
SACOL2570
(Staphylococcus
aureus) 		5 / 11 ALA A  15
GLY A 129
THR A 111
ALA A 112
ASP A  70
 None
 1.11A 2f16H-3fttA:
undetectable
2f16I-3fttA:
undetectable		 2f16H-3fttA:
19.91
2f16I-3fttA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3ftt PUTATIVE
ACETYLTRANSFERASE
SACOL2570
(Staphylococcus
aureus) 		5 / 11 ALA A  15
GLY A 129
THR A 111
ALA A 112
ASP A  70
 None
 1.08A 2f16V-3fttA:
undetectable
2f16W-3fttA:
undetectable		 2f16V-3fttA:
19.91
2f16W-3fttA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3ftt PUTATIVE
ACETYLTRANSFERASE
SACOL2570
(Staphylococcus
aureus) 		5 / 11 ALA A  15
GLY A 129
THR A 111
ALA A 112
ASP A  70
 None
 1.13A 3mg0V-3fttA:
undetectable
3mg0W-3fttA:
undetectable		 3mg0V-3fttA:
19.91
3mg0W-3fttA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA451_1
(CYTOCHROME P450
164A2)		 3ftt PUTATIVE
ACETYLTRANSFERASE
SACOL2570
(Staphylococcus
aureus) 		5 / 10 LEU A  49
ILE A  31
ALA A  28
THR A  69
VAL A  75
 None
 1.41A 3r9cA-3fttA:
undetectable		 3r9cA-3fttA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3ftt PUTATIVE
ACETYLTRANSFERASE
SACOL2570
(Staphylococcus
aureus) 		4 / 8 GLY A 108
PHE A 109
VAL A  81
SER A 135
 None
 0.92A 4acbB-3fttA:
undetectable
4acbC-3fttA:
undetectable		 4acbB-3fttA:
19.80
4acbC-3fttA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_A_REAA602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3ftt PUTATIVE
ACETYLTRANSFERASE
SACOL2570
(Staphylococcus
aureus) 		5 / 12 ILE A 151
GLY A 134
PHE A 109
CYH A 107
CYH A  87
 None
 1.48A 5fhzA-3fttA:
undetectable		 5fhzA-3fttA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 3ftt PUTATIVE
ACETYLTRANSFERASE
SACOL2570
(Staphylococcus
aureus) 		3 / 3 ILE A  65
ASN A  84
CYH A 107
 None
 0.88A 6bp4A-3fttA:
undetectable		 6bp4A-3fttA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3ftt PUTATIVE
ACETYLTRANSFERASE
SACOL2570
(Staphylococcus
aureus) 		4 / 5 ARG A  25
GLY A  92
ASN A  74
ASP A  91
 None
 1.39A 6dwjB-3fttA:
undetectable
6dwjD-3fttA:
undetectable		 6dwjB-3fttA:
14.36
6dwjD-3fttA:
14.36