SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fus'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GRM_A_DVAA8_0 (GRAMICIDIN A)	3fus	EXTERIOR MEMBRANE GLYCOPROTEIN GP120 (Simian immunodeficiency virus)	4 / 4	GLY A 275 VAL A 462 TRP A 273 TRP A 349	None	1.38A	1grmA-3fusA: undetectable	1grmA-3fusA: 2.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GRM_B_DVAB8_0 (GRAMICIDIN A)	3fus	EXTERIOR MEMBRANE GLYCOPROTEIN GP120 (Simian immunodeficiency virus)	4 / 4	GLY A 275 VAL A 462 TRP A 273 TRP A 349	None	1.38A	1grmB-3fusA: undetectable	1grmB-3fusA: 2.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RUK_L_ACTL611_0 (IMMUNOGLOBULIN IGG2A, HEAVY CHAIN IMMUNOGLOBULIN IGG2A, LIGHT CHAIN)	3fus	EXTERIOR MEMBRANE GLYCOPROTEIN GP120 (Simian immunodeficiency virus)	4 / 6	LEU A 407 TRP A 349 TRP A 273 PHE A 274	None	1.37A	1rukH-3fusA: undetectable 1rukL-3fusA: undetectable	1rukH-3fusA: 22.98 1rukL-3fusA: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PFJ_B_ADNB502_2 (ADENOSYLHOMOCYSTEINA SE)	3fus	EXTERIOR MEMBRANE GLYCOPROTEIN GP120 (Simian immunodeficiency virus)	4 / 6	GLU A 84 THR A 81 THR A 296 HIS A 290	None	1.18A	4pfjB-3fusA: undetectable	4pfjB-3fusA: 19.08

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GRM_A_DVAA8_0","GRAMICIDIN A","3fus","EXTERIOR MEMBRANE GLYCOPROTEIN GP120","Simian immunodeficiency virus",4,"GLY A 275;VAL A 462;TRP A 273;TRP A 349","None","1.38A","1grmA-3fusA:undetectable","1grmA-3fusA:2.91"],["1GRM_B_DVAB8_0","GRAMICIDIN A","3fus","EXTERIOR MEMBRANE GLYCOPROTEIN GP120","Simian immunodeficiency virus",4,"GLY A 275;VAL A 462;TRP A 273;TRP A 349","None","1.38A","1grmB-3fusA:undetectable","1grmB-3fusA:2.91"],["1RUK_L_ACTL611_0","IMMUNOGLOBULIN IGG2A, HEAVY CHAIN;IMMUNOGLOBULIN IGG2A, LIGHT CHAIN","3fus","EXTERIOR MEMBRANE GLYCOPROTEIN GP120","Simian immunodeficiency virus",4,"LEU A 407;TRP A 349;TRP A 273;PHE A 274","None","1.37A","1rukH-3fusA:undetectable;1rukL-3fusA:undetectable","1rukH-3fusA:22.98;1rukL-3fusA:19.37"],["4PFJ_B_ADNB502_2","ADENOSYLHOMOCYSTEINASE","3fus","EXTERIOR MEMBRANE GLYCOPROTEIN GP120","Simian immunodeficiency virus",4,"GLU A  84;THR A  81;THR A 296;HIS A 290","None","1.18A","4pfjB-3fusA:undetectable","4pfjB-3fusA:19.08"]]