SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fuy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3fuy PUTATIVE INTEGRON
GENE CASSETTE
PROTEIN
(uncultured
bacterium) 		4 / 7 ILE A 122
ILE A  73
ILE A  16
ASP A  46
 None
 0.88A 1uwjA-3fuyA:
undetectable		 1uwjA-3fuyA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_A_FOLA164_0
(DIHYDROFOLATE
REDUCTASE)		 3fuy PUTATIVE INTEGRON
GENE CASSETTE
PROTEIN
(uncultured
bacterium) 		5 / 12 ILE A  73
LEU A  45
LYS A  49
ARG A  52
TYR A 154
 None
 1.32A 2zzaA-3fuyA:
undetectable		 2zzaA-3fuyA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_B_FOLB164_0
(DIHYDROFOLATE
REDUCTASE)		 3fuy PUTATIVE INTEGRON
GENE CASSETTE
PROTEIN
(uncultured
bacterium) 		5 / 11 ILE A  73
LEU A  45
LYS A  49
ARG A  52
TYR A 154
 None
 1.07A 2zzaB-3fuyA:
undetectable		 2zzaB-3fuyA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL3_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3fuy PUTATIVE INTEGRON
GENE CASSETTE
PROTEIN
(uncultured
bacterium) 		5 / 12 ILE A  73
LEU A  45
LYS A  49
ARG A  52
TYR A 154
 None
 1.19A 3ql3A-3fuyA:
undetectable		 3ql3A-3fuyA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1N_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3fuy PUTATIVE INTEGRON
GENE CASSETTE
PROTEIN
(uncultured
bacterium) 		5 / 11 ILE A  73
LEU A  45
LYS A  49
ARG A  52
TYR A 154
 None
 1.39A 4i1nA-3fuyA:
undetectable		 4i1nA-3fuyA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLF_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3fuy PUTATIVE INTEGRON
GENE CASSETTE
PROTEIN
(uncultured
bacterium) 		5 / 11 ILE A  73
LEU A  45
LYS A  49
ARG A  52
TYR A 154
 None
 1.15A 4qlfA-3fuyA:
undetectable		 4qlfA-3fuyA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4USW_A_ACTA1470_0
(ADENYLATE CYCLASE
TYPE 10)		 3fuy PUTATIVE INTEGRON
GENE CASSETTE
PROTEIN
(uncultured
bacterium) 		4 / 6 LEU A   9
LEU A  27
VAL A  26
PHE A   8
 None
 1.22A 4uswA-3fuyA:
undetectable		 4uswA-3fuyA:
16.93