SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fvb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 IMD  A 171 (-3.4A)
FE  A 164 ( 2.5A)
None
None
 0.87A 1p7lD-3fvbA:
undetectable		 1p7lD-3fvbA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 IMD  A 171 (-3.4A)
FE  A 164 ( 2.5A)
None
None
 0.89A 1p7lC-3fvbA:
undetectable		 1p7lC-3fvbA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 IMD  A 171 (-3.4A)
FE  A 164 ( 2.5A)
None
None
 0.87A 1rg9B-3fvbA:
undetectable		 1rg9B-3fvbA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 IMD  A 171 (-3.4A)
FE  A 164 ( 2.5A)
None
None
 0.87A 1rg9A-3fvbA:
undetectable		 1rg9A-3fvbA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 IMD  A 171 (-3.4A)
FE  A 164 ( 2.5A)
None
None
 0.86A 1rg9D-3fvbA:
undetectable		 1rg9D-3fvbA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 IMD  A 171 (-3.4A)
FE  A 164 ( 2.5A)
None
None
 0.88A 1rg9C-3fvbA:
undetectable		 1rg9C-3fvbA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		5 / 11 GLU A  51
HIS A  54
GLU A  94
SER A 100
GLU A 127
 FE  A 164 ( 2.9A)
FE  A 164 (-3.3A)
IMD  A 171 (-3.2A)
None
FE  A 164 ( 2.5A)
 0.93A 1rnrA-3fvbA:
8.0		 1rnrA-3fvbA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		5 / 12 GLU A  51
HIS A  54
GLU A  94
SER A 100
GLU A 127
 FE  A 164 ( 2.9A)
FE  A 164 (-3.3A)
IMD  A 171 (-3.2A)
None
FE  A 164 ( 2.5A)
 0.98A 1rnrB-3fvbA:
9.0		 1rnrB-3fvbA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		4 / 6 LEU A  32
GLN A  24
LEU A  31
GLU A  44
 None
 0.95A 3h5gB-3fvbA:
undetectable
3h5gC-3fvbA:
undetectable		 3h5gB-3fvbA:
10.46
3h5gC-3fvbA:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		4 / 5 ALA A  21
GLU A 127
GLU A  94
ALA A  97
 IMD  A 171 (-3.4A)
FE  A 164 ( 2.5A)
IMD  A 171 (-3.2A)
IMD  A 171 (-3.4A)
 1.31A 3r9tC-3fvbA:
undetectable		 3r9tC-3fvbA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		4 / 7 PRO A  69
GLY A  67
ASP A  60
ARG A  61
 None
 0.82A 3ur0B-3fvbA:
undetectable		 3ur0B-3fvbA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOS_A_4KOA201_1
(UNCHARACTERIZED
PROTEIN)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		5 / 12 PRO A  76
ARG A  78
GLY A  93
PHE A  16
TYR A 101
 None
 1.29A 4kosA-3fvbA:
undetectable		 4kosA-3fvbA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		5 / 12 PRO A  76
ARG A  78
GLY A  93
PHE A  16
TYR A 101
 None
 1.29A 4kotA-3fvbA:
undetectable		 4kotA-3fvbA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		5 / 12 PRO A  76
ARG A  78
GLY A  93
PHE A  16
TYR A 101
 None
 1.31A 4kovA-3fvbA:
undetectable		 4kovA-3fvbA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOW_A_CFXA204_1
(UNCHARACTERIZED
PROTEIN)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		5 / 12 PRO A  76
ARG A  78
GLY A  93
PHE A  16
TYR A 101
 None
 1.33A 4kowA-3fvbA:
undetectable		 4kowA-3fvbA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOX_A_CLSA205_1
(UNCHARACTERIZED
PROTEIN)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		5 / 11 PRO A  76
ARG A  78
GLY A  93
PHE A  16
TYR A 101
 None
 1.31A 4koxA-3fvbA:
undetectable		 4koxA-3fvbA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 IMD  A 171 (-3.4A)
FE  A 164 ( 2.5A)
None
None
 0.88A 4kttB-3fvbA:
undetectable		 4kttB-3fvbA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 IMD  A 171 (-3.4A)
FE  A 164 ( 2.5A)
None
None
 0.89A 4ndnB-3fvbA:
undetectable		 4ndnB-3fvbA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 IMD  A 171 (-3.4A)
FE  A 164 ( 2.5A)
None
None
 0.88A 4ndnD-3fvbA:
undetectable		 4ndnD-3fvbA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 IMD  A 171 (-3.4A)
FE  A 164 ( 2.5A)
None
None
 0.94A 5t8sA-3fvbA:
undetectable		 5t8sA-3fvbA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHB_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		3 / 3 PHE A 133
ASP A  90
LEU A 123
 None
 0.74A 5uhbC-3fvbA:
undetectable		 5uhbC-3fvbA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHC_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		3 / 3 PHE A 133
ASP A  90
LEU A 123
 None
 0.77A 5uhcC-3fvbA:
undetectable		 5uhcC-3fvbA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		4 / 6 LEU A  40
GLN A 137
LEU A 138
LEU A 141
 None
 1.14A 5yvnA-3fvbA:
undetectable		 5yvnA-3fvbA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3fvb BACTERIOFERRITIN
(Brucella
abortus) 		4 / 7 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 IMD  A 171 (-3.4A)
FE  A 164 ( 2.5A)
None
None
 0.92A 6fbnA-3fvbA:
undetectable		 6fbnA-3fvbA:
17.97