SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fvc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.37A 1a4gB-3fvcA:
undetectable		 1a4gB-3fvcA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.27A 1nncA-3fvcA:
undetectable		 1nncA-3fvcA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		4 / 8 GLU A 321
GLY A 322
THR A 306
PHE A 303
 None
 1.04A 1ykiA-3fvcA:
undetectable
1ykiB-3fvcA:
undetectable		 1ykiA-3fvcA:
14.95
1ykiB-3fvcA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		4 / 8 THR A 306
PHE A 303
GLU A 321
GLY A 322
 None
 1.06A 1ykiA-3fvcA:
undetectable
1ykiB-3fvcA:
undetectable		 1ykiA-3fvcA:
14.95
1ykiB-3fvcA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		4 / 8 GLU A 321
GLY A 322
THR A 306
PHE A 303
 None
 1.07A 1ykiC-3fvcA:
undetectable
1ykiD-3fvcA:
undetectable		 1ykiC-3fvcA:
14.95
1ykiD-3fvcA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		4 / 8 THR A 306
PHE A 303
GLU A 321
GLY A 322
 None
 1.04A 1ykiC-3fvcA:
undetectable
1ykiD-3fvcA:
undetectable		 1ykiC-3fvcA:
14.95
1ykiD-3fvcA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.28A 2cmlA-3fvcA:
undetectable		 2cmlA-3fvcA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.26A 2cmlB-3fvcA:
undetectable		 2cmlB-3fvcA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.24A 2cmlC-3fvcA:
undetectable		 2cmlC-3fvcA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4477_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.30A 2cmlD-3fvcA:
undetectable		 2cmlD-3fvcA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 SER A 560
THR A 535
VAL A 536
LEU A 572
ILE A 578
 None
 1.36A 2fj1A-3fvcA:
undetectable		 2fj1A-3fvcA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 THR A 370
THR A 311
VAL A 332
GLY A 333
GLN A 366
 None
 1.27A 2x2iC-3fvcA:
undetectable		 2x2iC-3fvcA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_A_ZMRA1001_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.27A 3b7eA-3fvcA:
undetectable		 3b7eA-3fvcA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_B_ZMRB1002_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.27A 3b7eB-3fvcA:
undetectable		 3b7eB-3fvcA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_A_ZMRA901_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.25A 3sanA-3fvcA:
undetectable		 3sanA-3fvcA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_B_ZMRB901_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.24A 3sanB-3fvcA:
undetectable		 3sanB-3fvcA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_A_ZMRA1002_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.26A 3ti5A-3fvcA:
undetectable		 3ti5A-3fvcA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_B_ZMRB1002_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.25A 3ti5B-3fvcA:
undetectable		 3ti5B-3fvcA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_B_ZMRB1002_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.24A 3ticB-3fvcA:
undetectable		 3ticB-3fvcA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.24A 3ticC-3fvcA:
undetectable		 3ticC-3fvcA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_D_ZMRD1002_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.24A 3ticD-3fvcA:
undetectable		 3ticD-3fvcA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		3 / 3 PRO A 170
THR A 171
LEU A 207
 None
 0.78A 3ttrA-3fvcA:
undetectable		 3ttrA-3fvcA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.20A 4b7qA-3fvcA:
undetectable		 4b7qA-3fvcA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_B_ZMRB601_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.23A 4b7qB-3fvcA:
undetectable		 4b7qB-3fvcA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.30A 4b7qC-3fvcA:
undetectable		 4b7qC-3fvcA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_D_ZMRD601_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.31A 4b7qD-3fvcA:
undetectable		 4b7qD-3fvcA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.34A 4cpnA-3fvcA:
undetectable		 4cpnA-3fvcA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.35A 4cpzA-3fvcA:
undetectable		 4cpzA-3fvcA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.32A 4cpzB-3fvcA:
undetectable		 4cpzB-3fvcA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.37A 4cpzC-3fvcA:
undetectable		 4cpzC-3fvcA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.34A 4cpzD-3fvcA:
undetectable		 4cpzD-3fvcA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.38A 4cpzF-3fvcA:
undetectable		 4cpzF-3fvcA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.36A 4cpzG-3fvcA:
undetectable		 4cpzG-3fvcA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.34A 4cpzH-3fvcA:
undetectable		 4cpzH-3fvcA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		3 / 3 LEU A 107
ILE A 108
ARG A 201
 None
 0.69A 4mk4B-3fvcA:
undetectable		 4mk4B-3fvcA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		5 / 12 GLU A 289
ARG A 291
GLU A 242
ASN A 240
ARG A 273
 None
 1.25A 4mwrA-3fvcA:
undetectable		 4mwrA-3fvcA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		4 / 7 HIS A  77
ILE A 307
SER A 314
THR A 311
 None
 1.05A 5vkqA-3fvcA:
undetectable
5vkqD-3fvcA:
undetectable		 5vkqA-3fvcA:
17.06
5vkqD-3fvcA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		4 / 7 SER A 314
THR A 311
HIS A  77
ILE A 307
 None
 1.06A 5vkqA-3fvcA:
undetectable
5vkqB-3fvcA:
undetectable		 5vkqA-3fvcA:
17.06
5vkqB-3fvcA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		4 / 8 SER A 314
THR A 311
HIS A  77
ILE A 307
 None
 1.07A 5vkqB-3fvcA:
undetectable
5vkqC-3fvcA:
undetectable		 5vkqB-3fvcA:
17.06
5vkqC-3fvcA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3fvc GLYCOPROTEIN GP110
(Human
gammaherpesvirus
4) 		4 / 7 SER A 314
THR A 311
HIS A  77
ILE A 307
 None
 1.03A 5vkqC-3fvcA:
undetectable
5vkqD-3fvcA:
undetectable		 5vkqC-3fvcA:
17.06
5vkqD-3fvcA:
17.06