SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fvv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		 3fvv UNCHARACTERIZED
PROTEIN
(Bordetella
pertussis) 		4 / 7 ASP A  45
GLU A  49
PHE A  64
ARG A  43
 None
 1.33A 1b2iA-3fvvA:
undetectable		 1b2iA-3fvvA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 3fvv UNCHARACTERIZED
PROTEIN
(Bordetella
pertussis) 		5 / 12 LEU A  18
LEU A  16
THR A 122
VAL A 121
ALA A 128
 None
 1.20A 1n5xA-3fvvA:
undetectable		 1n5xA-3fvvA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 3fvv UNCHARACTERIZED
PROTEIN
(Bordetella
pertussis) 		5 / 12 LEU A  18
LEU A  16
THR A 122
VAL A 121
ALA A 128
 None
 1.20A 1n5xB-3fvvA:
undetectable		 1n5xB-3fvvA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_B_NCAB901_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 3fvv UNCHARACTERIZED
PROTEIN
(Bordetella
pertussis) 		4 / 5 ILE A 125
PRO A 124
PHE A  84
VAL A 121
 None
 1.49A 2hjhB-3fvvA:
5.0		 2hjhB-3fvvA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 3fvv UNCHARACTERIZED
PROTEIN
(Bordetella
pertussis) 		5 / 12 ALA A 136
THR A 115
GLY A  67
LEU A  69
LEU A  68
 None
SO4  A 233 (-3.8A)
None
None
None
 1.07A 2hw2A-3fvvA:
undetectable		 2hw2A-3fvvA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3fvv UNCHARACTERIZED
PROTEIN
(Bordetella
pertussis) 		5 / 12 MET A  85
LEU A  93
LEU A  16
SER A  20
VAL A 131
 None
 1.25A 2pnjB-3fvvA:
2.8		 2pnjB-3fvvA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3fvv UNCHARACTERIZED
PROTEIN
(Bordetella
pertussis) 		5 / 12 MET A  85
LEU A  93
LEU A  16
SER A  20
VAL A 131
 None
 1.19A 2po5A-3fvvA:
2.0		 2po5A-3fvvA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3fvv UNCHARACTERIZED
PROTEIN
(Bordetella
pertussis) 		5 / 11 MET A  85
LEU A  93
LEU A  16
SER A  20
VAL A 131
 None
 1.20A 2po5B-3fvvA:
3.5		 2po5B-3fvvA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 3fvv UNCHARACTERIZED
PROTEIN
(Bordetella
pertussis) 		5 / 12 HIS A 104
ILE A 201
LEU A   8
VAL A 197
GLY A 217
 None
 1.19A 5byjA-3fvvA:
undetectable		 5byjA-3fvvA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 3fvv UNCHARACTERIZED
PROTEIN
(Bordetella
pertussis) 		4 / 8 ASP A  19
SER A  20
GLY A 159
VAL A 114
 None
 1.11A 6giqL-3fvvA:
undetectable
6giqP-3fvvA:
undetectable
6giqT-3fvvA:
undetectable		 6giqL-3fvvA:
19.83
6giqP-3fvvA:
23.75
6giqT-3fvvA:
15.35