SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fw6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 3fw6 CELLULASE
(uncultured
bacterium) 		3 / 3 VAL A 105
TRP A 197
TRP A  83
 None
 0.92A 1c4dA-3fw6A:
undetectable
1c4dB-3fw6A:
undetectable		 1c4dA-3fw6A:
3.95
1c4dB-3fw6A:
3.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 3fw6 CELLULASE
(uncultured
bacterium) 		5 / 12 ILE A 402
ALA A 405
THR A 433
LEU A  55
ARG A 425
 None
 1.11A 1cbsA-3fw6A:
2.0		 1cbsA-3fw6A:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 3fw6 CELLULASE
(uncultured
bacterium) 		4 / 8 ILE A 217
PHE A 113
HIS A  71
LEU A  70
 None
 0.74A 1fslB-3fw6A:
undetectable		 1fslB-3fw6A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 3fw6 CELLULASE
(uncultured
bacterium) 		4 / 5 VAL A 467
ASN A 486
VAL A  35
ILE A  37
 None
 0.90A 1z2bC-3fw6A:
undetectable		 1z2bC-3fw6A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)		 3fw6 CELLULASE
(uncultured
bacterium) 		5 / 12 ILE A 402
ALA A 405
THR A 433
LEU A  55
ARG A 425
 None
 1.00A 2fr3A-3fw6A:
undetectable		 2fr3A-3fw6A:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 3fw6 CELLULASE
(uncultured
bacterium) 		4 / 8 ALA A 451
VAL A 545
THR A 481
ASP A 446
 None
 1.12A 2kotB-3fw6A:
undetectable		 2kotB-3fw6A:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 3fw6 CELLULASE
(uncultured
bacterium) 		6 / 12 ASN A 220
GLU A 221
HIS A 328
TYR A 330
GLU A 393
TRP A 426
 None
 0.75A 2v3dA-3fw6A:
15.3		 2v3dA-3fw6A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 3fw6 CELLULASE
(uncultured
bacterium) 		3 / 3 TYR A  53
TYR A 394
ILE A 411
 None
 0.83A 3eteA-3fw6A:
undetectable
3eteB-3fw6A:
undetectable		 3eteA-3fw6A:
22.81
3eteB-3fw6A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_1
(REPRESSOR PROTEIN
MPHR(A))		 3fw6 CELLULASE
(uncultured
bacterium) 		4 / 7 ASN A 180
TYR A 152
ARG A 230
ALA A 145
 None
 1.40A 3frqB-3fw6A:
undetectable		 3frqB-3fw6A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3fw6 CELLULASE
(uncultured
bacterium) 		4 / 6 ILE A  37
VAL A  39
LEU A 499
LEU A 532
 None
 0.82A 3kp6A-3fw6A:
undetectable
3kp6B-3fw6A:
undetectable		 3kp6A-3fw6A:
14.15
3kp6B-3fw6A:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 3fw6 CELLULASE
(uncultured
bacterium) 		5 / 12 VAL A 482
LEU A 527
LEU A 499
VAL A 525
ALA A 508
 None
 0.93A 3pghC-3fw6A:
undetectable		 3pghC-3fw6A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 3fw6 CELLULASE
(uncultured
bacterium) 		4 / 5 PHE A 113
ILE A 126
GLY A  74
HIS A  71
 None
 1.25A 3r0lD-3fw6A:
undetectable		 3r0lD-3fw6A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_D_ACHD301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3fw6 CELLULASE
(uncultured
bacterium) 		4 / 8 TYR A  81
THR A 112
TYR A  73
TRP A 197
 None
 1.49A 3wipD-3fw6A:
undetectable
3wipE-3fw6A:
undetectable		 3wipD-3fw6A:
17.78
3wipE-3fw6A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYS_A_ACTA402_0
(MCCC FAMILY PROTEIN)		 3fw6 CELLULASE
(uncultured
bacterium) 		4 / 6 SER A 354
ASP A 357
ASP A 465
GLU A 363
 None
 1.00A 4eysA-3fw6A:
2.1		 4eysA-3fw6A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 3fw6 CELLULASE
(uncultured
bacterium) 		4 / 7 PRO A 222
ASP A 219
HIS A 229
SER A  79
 None
 1.23A 4k7gB-3fw6A:
undetectable		 4k7gB-3fw6A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 3fw6 CELLULASE
(uncultured
bacterium) 		4 / 8 TYR A 249
ILE A 128
GLN A 194
VAL A 134
 None
 0.89A 4ma7A-3fw6A:
undetectable		 4ma7A-3fw6A:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 3fw6 CELLULASE
(uncultured
bacterium) 		4 / 8 LEU A 420
GLY A 419
GLU A 418
ALA A 472
 None
 0.74A 4rjdA-3fw6A:
undetectable
4rjdB-3fw6A:
undetectable		 4rjdA-3fw6A:
8.83
4rjdB-3fw6A:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_A_15UA301_1
(THROMBIN HEAVY CHAIN)		 3fw6 CELLULASE
(uncultured
bacterium) 		5 / 10 LEU A 213
TRP A 205
ALA A 260
ALA A 124
GLY A 211
 None
 1.34A 4rn6A-3fw6A:
undetectable		 4rn6A-3fw6A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZ7_A_1E8A901_1
(CGMP-DEPENDENT
PROTEIN KINASE,
PUTATIVE)		 3fw6 CELLULASE
(uncultured
bacterium) 		5 / 10 ALA A  58
THR A 435
ILE A 439
LEU A  63
VAL A  68
 None
 1.02A 4rz7A-3fw6A:
2.7		 4rz7A-3fw6A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3fw6 CELLULASE
(uncultured
bacterium) 		4 / 7 ILE A 497
LEU A 532
THR A 493
LEU A 536
 None
 1.01A 5b1bA-3fw6A:
undetectable
5b1bJ-3fw6A:
undetectable		 5b1bA-3fw6A:
21.44
5b1bJ-3fw6A:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3fw6 CELLULASE
(uncultured
bacterium) 		4 / 8 VAL A 457
GLY A 453
SER A 475
GLY A 478
 None
 0.86A 5e26C-3fw6A:
undetectable
5e26D-3fw6A:
undetectable		 5e26C-3fw6A:
21.34
5e26D-3fw6A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)		 3fw6 CELLULASE
(uncultured
bacterium) 		5 / 12 GLY A 272
GLN A 280
LEU A 310
GLY A 250
PHE A 325
 None
 1.06A 5fsaB-3fw6A:
undetectable		 5fsaB-3fw6A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 3fw6 CELLULASE
(uncultured
bacterium) 		3 / 3 ARG A  72
ASN A 220
ASP A  88
 None
 0.90A 5gwxA-3fw6A:
undetectable		 5gwxA-3fw6A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3fw6 CELLULASE
(uncultured
bacterium) 		4 / 7 ILE A 217
HIS A  71
LEU A  70
ALA A 424
 None
 0.88A 5hrqE-3fw6A:
undetectable
5hrqF-3fw6A:
undetectable
5hrqJ-3fw6A:
undetectable		 5hrqE-3fw6A:
3.74
5hrqF-3fw6A:
5.23
5hrqJ-3fw6A:
5.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3fw6 CELLULASE
(uncultured
bacterium) 		5 / 12 GLU A 399
LEU A 513
ALA A 405
ARG A 425
PRO A 429
 None
 1.27A 5nd4B-3fw6A:
undetectable		 5nd4B-3fw6A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3fw6 CELLULASE
(uncultured
bacterium) 		5 / 12 SER A 476
ALA A 548
TYR A 445
ALA A 479
GLY A 478
 None
 1.10A 5tzoA-3fw6A:
undetectable		 5tzoA-3fw6A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3fw6 CELLULASE
(uncultured
bacterium) 		5 / 12 SER A 476
ALA A 548
TYR A 445
ALA A 479
GLY A 478
 None
 1.07A 5tzoC-3fw6A:
undetectable		 5tzoC-3fw6A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3fw6 CELLULASE
(uncultured
bacterium) 		4 / 5 GLN A 512
VAL A 541
PRO A 537
THR A 407
 None
 1.37A 6cduA-3fw6A:
undetectable
6cduB-3fw6A:
undetectable		 6cduA-3fw6A:
22.84
6cduB-3fw6A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3fw6 CELLULASE
(uncultured
bacterium) 		5 / 7 ALA A 409
THR A 407
GLN A 512
VAL A 541
PRO A 537
 None
 1.44A 6cduA-3fw6A:
undetectable
6cduE-3fw6A:
undetectable		 6cduA-3fw6A:
22.84
6cduE-3fw6A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_B_EY4B500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3fw6 CELLULASE
(uncultured
bacterium) 		5 / 6 GLN A 512
VAL A 541
PRO A 537
ALA A 409
THR A 407
 None
 1.36A 6cduB-3fw6A:
undetectable
6cduC-3fw6A:
undetectable		 6cduB-3fw6A:
22.84
6cduC-3fw6A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3fw6 CELLULASE
(uncultured
bacterium) 		5 / 8 GLN A 512
VAL A 541
PRO A 537
ALA A 409
THR A 407
 None
 1.38A 6cduD-3fw6A:
undetectable
6cduE-3fw6A:
undetectable		 6cduD-3fw6A:
22.84
6cduE-3fw6A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3fw6 CELLULASE
(uncultured
bacterium) 		5 / 7 ALA A 409
THR A 407
GLN A 512
VAL A 541
PRO A 537
 None
 1.37A 6cduF-3fw6A:
undetectable
6cduJ-3fw6A:
undetectable		 6cduF-3fw6A:
22.84
6cduJ-3fw6A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3fw6 CELLULASE
(uncultured
bacterium) 		5 / 7 GLN A 512
VAL A 541
PRO A 537
ALA A 409
THR A 407
 None
 1.43A 6cduH-3fw6A:
undetectable
6cduI-3fw6A:
undetectable		 6cduH-3fw6A:
22.84
6cduI-3fw6A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3fw6 CELLULASE
(uncultured
bacterium) 		4 / 5 GLN A 512
VAL A 541
PRO A 537
THR A 407
 None
 1.34A 6cduI-3fw6A:
undetectable
6cduJ-3fw6A:
undetectable		 6cduI-3fw6A:
22.84
6cduJ-3fw6A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3fw6 CELLULASE
(uncultured
bacterium) 		4 / 6 GLY A 334
ASP A 339
ARG A 347
ARG A 348
 None
 1.21A 6dwdA-3fw6A:
undetectable
6dwdC-3fw6A:
undetectable		 6dwdA-3fw6A:
23.08
6dwdC-3fw6A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3fw6 CELLULASE
(uncultured
bacterium) 		4 / 5 GLY A 334
ASP A 339
ARG A 347
ARG A 348
 None
 1.22A 6dwdB-3fw6A:
undetectable
6dwdD-3fw6A:
undetectable		 6dwdB-3fw6A:
23.08
6dwdD-3fw6A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3fw6 CELLULASE
(uncultured
bacterium) 		4 / 5 ARG A 347
ARG A 348
GLY A 334
ASP A 339
 None
 1.28A 6dwjB-3fw6A:
undetectable
6dwjD-3fw6A:
undetectable		 6dwjB-3fw6A:
23.08
6dwjD-3fw6A:
23.08