SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fwr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 3fwr YQZB PROTEIN
(Bacillus
subtilis) 		4 / 8 ALA A 167
THR A 110
VAL A 123
PHE A 112
 None
ADP  A 221 ( 3.9A)
None
None
 0.97A 4ltwA-3fwrA:
undetectable		 4ltwA-3fwrA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3fwr YQZB PROTEIN
(Bacillus
subtilis) 		4 / 9 ILE A 175
VAL A 123
THR A 149
ASN A 153
 ADP  A 221 (-3.7A)
None
ADP  A 221 (-3.7A)
None
 0.78A 5lg3I-3fwrA:
undetectable		 5lg3I-3fwrA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 3fwr YQZB PROTEIN
(Bacillus
subtilis) 		3 / 3 VAL A 108
LYS A 196
MET A 199
 None
 1.09A 5nknA-3fwrA:
undetectable		 5nknA-3fwrA:
20.69