SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fwu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QHF_A_ACTA503_0 (CHORISMATE SYNTHASE)	3fwu	MACROPHAGE MIGRATION INHIBITORY FACTOR-LIKE PROTEIN (Leishmania major)	4 / 5	GLN A 21 ARG A 24 ALA A 25 ARG A 28	None	1.37A	2qhfA-3fwuA: undetectable	2qhfA-3fwuA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3O01_B_DXCB1_0 (CELL INVASION PROTEIN SIPD)	3fwu	MACROPHAGE MIGRATION INHIBITORY FACTOR-LIKE PROTEIN (Leishmania major)	5 / 9	ILE A 95 PHE A 42 ASN A 18 ALA A 83 VAL A 22	None	1.45A	3o01A-3fwuA: 2.0 3o01B-3fwuA: undetectable	3o01A-3fwuA: 15.11 3o01B-3fwuA: 15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DR5_A_SRYA1860_1 (16S RRNA 30S RIBOSOMAL PROTEIN S12)	3fwu	MACROPHAGE MIGRATION INHIBITORY FACTOR-LIKE PROTEIN (Leishmania major)	3 / 3	LYS A 33 PRO A 34 LYS A 0	None	1.40A	4dr5L-3fwuA: undetectable	4dr5L-3fwuA: 17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DR6_A_SRYA1956_1 (16S RRNA 30S RIBOSOMAL PROTEIN S12)	3fwu	MACROPHAGE MIGRATION INHIBITORY FACTOR-LIKE PROTEIN (Leishmania major)	3 / 3	LYS A 33 PRO A 34 LYS A 0	None	1.41A	4dr6L-3fwuA: undetectable	4dr6L-3fwuA: 17.02

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QHF_A_ACTA503_0","CHORISMATE SYNTHASE","3fwu","MACROPHAGE MIGRATION INHIBITORY FACTOR-LIKE PROTEIN","Leishmania major",4,"GLN A  21;ARG A  24;ALA A  25;ARG A  28","None","1.37A","2qhfA-3fwuA:undetectable","2qhfA-3fwuA:14.88"],["3O01_B_DXCB1_0","CELL INVASION PROTEIN SIPD","3fwu","MACROPHAGE MIGRATION INHIBITORY FACTOR-LIKE PROTEIN","Leishmania major",5,"ILE A  95;PHE A  42;ASN A  18;ALA A  83;VAL A  22","None","1.45A","3o01A-3fwuA:2.0;3o01B-3fwuA:undetectable","3o01A-3fwuA:15.11;3o01B-3fwuA:15.11"],["4DR5_A_SRYA1860_1","16S RRNA;30S RIBOSOMAL PROTEIN S12","3fwu","MACROPHAGE MIGRATION INHIBITORY FACTOR-LIKE PROTEIN","Leishmania major",3,"LYS A  33;PRO A  34;LYS A   0","None","1.40A","4dr5L-3fwuA:undetectable","4dr5L-3fwuA:17.02"],["4DR6_A_SRYA1956_1","16S RRNA;30S RIBOSOMAL PROTEIN S12","3fwu","MACROPHAGE MIGRATION INHIBITORY FACTOR-LIKE PROTEIN","Leishmania major",3,"LYS A  33;PRO A  34;LYS A   0","None","1.41A","4dr6L-3fwuA:undetectable","4dr6L-3fwuA:17.02"]]