SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fwx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 3fwx PEPTIDE DEFORMYLASE
(Vibrio
cholerae) 		4 / 4 ILE A  45
MET A  71
VAL A 107
GLY A  46
 None
 1.23A 1e06B-3fwxA:
undetectable		 1e06B-3fwxA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 3fwx PEPTIDE DEFORMYLASE
(Vibrio
cholerae) 		4 / 8 PHE A 143
VAL A 144
HIS A 137
ALA A  48
 None
None
ZN  A 170 (-3.1A)
None
 0.96A 4eyzA-3fwxA:
undetectable		 4eyzA-3fwxA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 3fwx PEPTIDE DEFORMYLASE
(Vibrio
cholerae) 		4 / 8 PHE A 143
VAL A 144
HIS A 137
ALA A  48
 None
None
ZN  A 170 (-3.1A)
None
 0.95A 4eyzB-3fwxA:
undetectable		 4eyzB-3fwxA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AGG_Z_AG2Z503_0
(TRNA(ILE2)
2-AGMATINYLCYTIDINE
SYNTHETASE TIAS)		 3fwx PEPTIDE DEFORMYLASE
(Vibrio
cholerae) 		4 / 5 GLU A  89
VAL A 131
CYH A 130
ARG A 103
 None
 1.31A 6aggZ-3fwxA:
0.0		 6aggZ-3fwxA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3fwx PEPTIDE DEFORMYLASE
(Vibrio
cholerae) 		3 / 3 HIS A 137
HIS A 133
ARG A 103
 ZN  A 170 (-3.1A)
ZN  A 170 (-3.3A)
None
 1.10A 6b58A-3fwxA:
undetectable		 6b58A-3fwxA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3fwx PEPTIDE DEFORMYLASE
(Vibrio
cholerae) 		3 / 3 ARG A 154
LYS A 151
ARG A 103
 None
 1.19A 6c06D-3fwxA:
undetectable		 6c06D-3fwxA:
undetectable