SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fxt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 3fxt NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		3 / 3 ALA A  80
VAL A  82
TRP A  85
 None
 0.76A 1nt5A-3fxtA:
undetectable		 1nt5A-3fxtA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 3fxt NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		3 / 3 ALA A  80
VAL A  82
TRP A  85
 None
 0.76A 1nt5B-3fxtA:
undetectable		 1nt5B-3fxtA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 3fxt NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		3 / 3 ALA A  80
VAL A  82
TRP A  85
 None
 0.86A 1nt6A-3fxtA:
undetectable		 1nt6A-3fxtA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 3fxt NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		3 / 3 ALA A  80
VAL A  82
TRP A  85
 None
 0.86A 1nt6B-3fxtA:
undetectable		 1nt6B-3fxtA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3fxt NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 7 LEU A  95
ILE A  97
PHE A 104
ALA A 108
 None
 0.99A 1oniB-3fxtA:
undetectable
1oniC-3fxtA:
undetectable		 1oniB-3fxtA:
20.86
1oniC-3fxtA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 3fxt NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		3 / 3 TRP A  85
GLN A  83
TRP A 128
 None
 0.81A 2vqyA-3fxtA:
5.5		 2vqyA-3fxtA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 3fxt NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		5 / 10 LEU A 125
ILE A  56
VAL A  58
GLY A  77
LEU A  95
 None
 1.01A 3ogqA-3fxtA:
undetectable		 3ogqA-3fxtA:
16.67