SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fy3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3fy3 HEMOLYSIN
(Proteus
mirabilis) 		5 / 12 ILE A 252
GLY A 217
SER A 230
GLY A 260
SER A 259
 None
 1.12A 1kiaA-3fy3A:
undetectable		 1kiaA-3fy3A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3fy3 HEMOLYSIN
(Proteus
mirabilis) 		5 / 12 ILE A 252
GLY A 217
SER A 230
GLY A 260
SER A 259
 None
 1.07A 1nbiA-3fy3A:
undetectable		 1nbiA-3fy3A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3fy3 HEMOLYSIN
(Proteus
mirabilis) 		5 / 12 ILE A 252
GLY A 217
SER A 230
GLY A 260
SER A 259
 None
 1.08A 1nbiB-3fy3A:
undetectable		 1nbiB-3fy3A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3fy3 HEMOLYSIN
(Proteus
mirabilis) 		5 / 12 GLY A 205
ALA A 209
ILE A 212
LEU A 196
LEU A 157
 None
 1.01A 3adsB-3fy3A:
undetectable		 3adsB-3fy3A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3fy3 HEMOLYSIN
(Proteus
mirabilis) 		4 / 7 GLY A  77
GLN A  51
VAL A  73
ILE A 150
 None
 0.89A 3fi0P-3fy3A:
undetectable		 3fi0P-3fy3A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3fy3 HEMOLYSIN
(Proteus
mirabilis) 		3 / 3 ARG A 251
ARG A 154
ASP A 226
 None
 1.00A 3wipG-3fy3A:
undetectable
3wipH-3fy3A:
undetectable		 3wipG-3fy3A:
20.91
3wipH-3fy3A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3fy3 HEMOLYSIN
(Proteus
mirabilis) 		5 / 11 GLY A 205
ALA A 209
ILE A 212
LEU A 196
LEU A 157
 None
 0.99A 4xumB-3fy3A:
undetectable		 4xumB-3fy3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 3fy3 HEMOLYSIN
(Proteus
mirabilis) 		5 / 12 ILE A 109
VAL A  56
TYR A  68
GLY A 160
TYR A 172
 None
 1.01A 5uxdB-3fy3A:
undetectable		 5uxdB-3fy3A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 3fy3 HEMOLYSIN
(Proteus
mirabilis) 		4 / 5 GLY A 148
LEU A 188
SER A 155
TYR A 134
 None
 1.35A 6ji6A-3fy3A:
undetectable		 6ji6A-3fy3A:
18.90