SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fy4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13GS_A_SASA211_1
(GLUTATHIONE
S-TRANSFERASE)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		5 / 10 ARG A 439
ILE A 453
TYR A 454
PRO A 249
GLY A 428
 None
 1.48A 13gsA-3fy4A:
undetectable		 13gsA-3fy4A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13GS_B_SASB211_1
(GLUTATHIONE
S-TRANSFERASE)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		5 / 9 ARG A 439
ILE A 453
TYR A 454
PRO A 249
GLY A 428
 None
 1.48A 13gsB-3fy4A:
undetectable		 13gsB-3fy4A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		5 / 12 TYR A 437
PHE A 441
VAL A 259
PHE A 218
ALA A 366
 None
None
FAD  A 900 (-3.8A)
None
None
 1.24A 1q23A-3fy4A:
undetectable
1q23B-3fy4A:
undetectable		 1q23A-3fy4A:
16.54
1q23B-3fy4A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		6 / 12 GLY A 342
ILE A 352
ALA A 337
VAL A 370
LEU A 374
LEU A 379
 None
 1.15A 2yqzA-3fy4A:
2.2		 2yqzA-3fy4A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		6 / 12 GLY A 342
ILE A 352
ALA A 337
VAL A 370
LEU A 374
LEU A 379
 None
 1.14A 2yqzB-3fy4A:
3.3		 2yqzB-3fy4A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		4 / 7 SER A 172
SER A 140
GLU A 110
ASP A 112
 None
 1.31A 3bc9A-3fy4A:
undetectable		 3bc9A-3fy4A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		4 / 8 HIS A 368
ASN A 405
TRP A 408
TRP A 301
 MES  A 920 ( 4.1A)
FAD  A 900 ( 3.4A)
MES  A 920 (-4.0A)
MES  A 920 ( 3.6A)
 1.17A 3ccfB-3fy4A:
3.3		 3ccfB-3fy4A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		5 / 12 LEU A  80
GLY A  81
LEU A 185
LEU A  73
ASP A  74
 None
 0.94A 3gwvA-3fy4A:
undetectable		 3gwvA-3fy4A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		3 / 3 LEU A 379
LEU A 374
ARG A 340
 None
 0.73A 3hcnB-3fy4A:
3.1		 3hcnB-3fy4A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		3 / 3 PRO A 460
LEU A 461
GLN A 464
 None
 0.65A 3hznG-3fy4A:
undetectable
3hznH-3fy4A:
undetectable		 3hznG-3fy4A:
18.89
3hznH-3fy4A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_1
(METHYLTRANSFERASE)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		5 / 9 GLY A  14
GLU A 110
SER A 140
HIS A  18
TYR A 182
 None
 1.16A 3ndiA-3fy4A:
2.6		 3ndiA-3fy4A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		4 / 8 LEU A 165
TYR A 161
PHE A 164
TYR A 275
 None
 1.16A 3po7A-3fy4A:
undetectable		 3po7A-3fy4A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		3 / 3 LEU A 226
ARG A 272
ASN A 280
 None
 0.70A 3qxvD-3fy4A:
undetectable		 3qxvD-3fy4A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		5 / 12 ASN A 153
GLY A 311
GLY A 155
ASP A 114
PHE A 315
 None
 1.39A 3r24A-3fy4A:
undetectable		 3r24A-3fy4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		3 / 3 ARG A  16
GLU A 110
ASN A  20
 None
 0.81A 4imaD-3fy4A:
undetectable		 4imaD-3fy4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		3 / 3 ARG A  16
GLU A 110
ASN A  20
 None
 0.80A 4ip7D-3fy4A:
3.4		 4ip7D-3fy4A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_C_CLQC1079_0
(SAPOSIN-B)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		4 / 5 ARG A  64
MET A  44
GLU A 211
LEU A 202
 None
 1.48A 4v2oA-3fy4A:
0.0
4v2oC-3fy4A:
0.0		 4v2oA-3fy4A:
9.39
4v2oC-3fy4A:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		4 / 6 LEU A 296
LEU A 299
PHE A 144
LEU A 165
 None
FAD  A 900 ( 4.9A)
None
None
 0.78A 5gs4A-3fy4A:
undetectable		 5gs4A-3fy4A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		3 / 3 ASP A 398
ASN A 405
PHE A 310
 None
FAD  A 900 ( 3.4A)
None
 0.74A 5jglB-3fy4A:
1.8		 5jglB-3fy4A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		4 / 5 PRO A 478
GLY A 345
THR A 344
LYS A 343
 None
 1.24A 5x23A-3fy4A:
undetectable		 5x23A-3fy4A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		5 / 12 LEU A 194
GLY A  89
TYR A 117
LEU A 120
LEU A  66
 None
 1.24A 5y2tA-3fy4A:
undetectable		 5y2tA-3fy4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_0
(SERUM ALBUMIN)		 3fy4 6-4 PHOTOLYASE
(Arabidopsis
thaliana) 		5 / 12 VAL A 135
LEU A  23
ARG A  12
PHE A  11
LEU A  84
 None
 1.42A 6a7pB-3fy4A:
undetectable		 6a7pB-3fy4A:
21.84