SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fy6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XOQ_B_ROFB501_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	3fy6	INTEGRON CASSETTE PROTEIN (Vibrio cholerae)	3 / 3	MET A 28 ASN A 71 GLN A 55	None	0.91A	1xoqB-3fy6A: undetectable	1xoqB-3fy6A: 17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FK8_A_SAMA302_1 (METHOXY MYCOLIC ACID SYNTHASE 4)	3fy6	INTEGRON CASSETTE PROTEIN (Vibrio cholerae)	3 / 3	SER A 50 THR A 69 GLN A 55	None	0.74A	2fk8A-3fy6A: undetectable	2fk8A-3fy6A: 18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUF_B_SUEB1201_3 (NS3 PROTEASE, NS4A PROTEIN)	3fy6	INTEGRON CASSETTE PROTEIN (Vibrio cholerae)	4 / 5	SER A 10 PRO A 65 TYR A 64 VAL A 101	None	0.92A	3sufC-3fy6A: undetectable	3sufC-3fy6A: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TUD_A_ERMA2001_2 (5-HYDROXYTRYPTAMINE RECEPTOR 2B,SOLUBLE CYTOCHROME B562 CHIMERA)	3fy6	INTEGRON CASSETTE PROTEIN (Vibrio cholerae)	4 / 7	THR A 53 VAL A 104 GLN A 99 GLU A 95	None	0.99A	5tudA-3fy6A: 2.4	5tudA-3fy6A: 15.24

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1XOQ_B_ROFB501_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D","3fy6","INTEGRON CASSETTE PROTEIN","Vibrio cholerae",3,"MET A  28;ASN A  71;GLN A  55","None","0.91A","1xoqB-3fy6A:undetectable","1xoqB-3fy6A:17.34"],["2FK8_A_SAMA302_1","METHOXY MYCOLIC ACID SYNTHASE 4","3fy6","INTEGRON CASSETTE PROTEIN","Vibrio cholerae",3,"SER A  50;THR A  69;GLN A  55","None","0.74A","2fk8A-3fy6A:undetectable","2fk8A-3fy6A:18.67"],["3SUF_B_SUEB1201_3","NS3 PROTEASE, NS4A PROTEIN;NS3 PROTEASE, NS4A PROTEIN","3fy6","INTEGRON CASSETTE PROTEIN","Vibrio cholerae",4,"SER A  10;PRO A  65;TYR A  64;VAL A 101","None","0.92A","3sufC-3fy6A:undetectable","3sufC-3fy6A:19.90"],["5TUD_A_ERMA2001_2","5-HYDROXYTRYPTAMINE RECEPTOR 2B,SOLUBLE CYTOCHROME B562 CHIMERA","3fy6","INTEGRON CASSETTE PROTEIN","Vibrio cholerae",4,"THR A  53;VAL A 104;GLN A  99;GLU A  95","None","0.99A","5tudA-3fy6A:2.4","5tudA-3fy6A:15.24"]]