SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fy7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 3fy7 CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 3
(Homo
sapiens) 		4 / 7 LEU A   6
LEU A  34
GLY A  36
LEU A  86
 None
 0.84A 1gtiA-3fy7A:
13.1		 1gtiA-3fy7A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3fy7 CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 3
(Homo
sapiens) 		5 / 12 THR A 218
CYH A 219
PRO A 220
VAL A  10
LEU A  41
 None
 1.19A 1z9hA-3fy7A:
9.8		 1z9hA-3fy7A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3fy7 CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 3
(Homo
sapiens) 		5 / 12 THR A 218
CYH A 219
PRO A 220
VAL A  10
LEU A  41
 None
 1.19A 1z9hB-3fy7A:
9.8		 1z9hB-3fy7A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3fy7 CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 3
(Homo
sapiens) 		5 / 12 THR A 218
CYH A 219
PRO A 220
VAL A  10
LEU A  41
 None
 1.19A 1z9hC-3fy7A:
3.3		 1z9hC-3fy7A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3fy7 CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 3
(Homo
sapiens) 		5 / 12 THR A 218
CYH A 219
PRO A 220
VAL A  10
LEU A  41
 None
 1.20A 1z9hD-3fy7A:
9.8		 1z9hD-3fy7A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 3fy7 CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 3
(Homo
sapiens) 		4 / 6 LEU A 176
ALA A 172
LEU A 177
THR A 170
 None
 1.03A 2roxB-3fy7A:
undetectable		 2roxB-3fy7A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA302_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 3fy7 CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 3
(Homo
sapiens) 		4 / 6 LEU A 156
GLU A 153
PRO A 154
ARG A 160
 None
 1.34A 3ltwA-3fy7A:
undetectable		 3ltwA-3fy7A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 3fy7 CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 3
(Homo
sapiens) 		5 / 12 VAL A 108
HIS A  21
ILE A 225
LEU A 206
VAL A 202
 None
 0.96A 3sp9B-3fy7A:
undetectable		 3sp9B-3fy7A:
25.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3fy7 CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 3
(Homo
sapiens) 		5 / 11 ALA A 151
GLY A 152
GLU A 153
GLY A 166
TYR A  98
 None
 1.30A 4e47B-3fy7A:
undetectable		 4e47B-3fy7A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 3fy7 CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 3
(Homo
sapiens) 		4 / 6 LEU A 176
ALA A 172
LEU A 177
THR A 170
 None
 1.03A 4i89A-3fy7A:
undetectable		 4i89A-3fy7A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3fy7 CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 3
(Homo
sapiens) 		5 / 11 ALA A 151
GLY A 152
GLU A 153
GLY A 166
TYR A  98
 None
 1.31A 4jdsB-3fy7A:
undetectable		 4jdsB-3fy7A:
22.84