SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fyf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3fyf PROTEIN BVU-3222
(Bacteroides
vulgatus) 		3 / 3 THR A 160
ASP A  71
SER A  85
 None
 0.83A 2nxeB-3fyfA:
undetectable		 2nxeB-3fyfA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3fyf PROTEIN BVU-3222
(Bacteroides
vulgatus) 		5 / 12 LEU A  68
VAL A  67
THR A 166
SER A 172
TYR A 141
 None
 1.44A 2y00B-3fyfA:
undetectable		 2y00B-3fyfA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3fyf PROTEIN BVU-3222
(Bacteroides
vulgatus) 		5 / 12 LEU A  68
VAL A  67
THR A 166
SER A 172
TYR A 141
 None
 1.44A 2y01B-3fyfA:
undetectable		 2y01B-3fyfA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3fyf PROTEIN BVU-3222
(Bacteroides
vulgatus) 		5 / 11 ALA A 102
ASN A 109
VAL A  83
ILE A  79
THR A  87
 None
 1.14A 3fl9C-3fyfA:
undetectable		 3fl9C-3fyfA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 3fyf PROTEIN BVU-3222
(Bacteroides
vulgatus) 		4 / 8 ALA A 163
ASN A 161
THR A 160
ALA A  57
 None
 0.88A 3hrdA-3fyfA:
undetectable
3hrdB-3fyfA:
undetectable		 3hrdA-3fyfA:
16.94
3hrdB-3fyfA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 3fyf PROTEIN BVU-3222
(Bacteroides
vulgatus) 		4 / 7 VAL A  90
ILE A  99
VAL A 152
ILE A 154
 None
 0.69A 5bmvC-3fyfA:
undetectable		 5bmvC-3fyfA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3fyf PROTEIN BVU-3222
(Bacteroides
vulgatus) 		5 / 12 THR A 119
VAL A 124
GLY A 122
PHE A 106
VAL A 165
 None
 1.12A 6a94B-3fyfA:
undetectable		 6a94B-3fyfA:
17.02