SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fza'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3fza GLUTAREDOXIN
(Populus
tremula
x
Populus
tremuloides) 		4 / 7 VAL A  64
LEU A  68
TYR A  24
ALA A  11
 None
 0.89A 1pthB-3fzaA:
undetectable		 1pthB-3fzaA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3fza GLUTAREDOXIN
(Populus
tremula
x
Populus
tremuloides) 		4 / 7 LEU A  42
VAL A  44
VAL A  77
ILE A  79
 None
 0.97A 1t87B-3fzaA:
undetectable		 1t87B-3fzaA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 3fza GLUTAREDOXIN
(Populus
tremula
x
Populus
tremuloides) 		4 / 8 THR A  69
ILE A  84
ASN A  76
GLN A  71
 None
 0.92A 2a8tB-3fzaA:
undetectable		 2a8tB-3fzaA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3fza GLUTAREDOXIN
(Populus
tremula
x
Populus
tremuloides) 		4 / 5 VAL A  64
LEU A  68
TYR A  24
ALA A  11
 None
 0.94A 3n8yB-3fzaA:
undetectable		 3n8yB-3fzaA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA504_1
(CYTOCHROME P450 2B4)		 3fza GLUTAREDOXIN
(Populus
tremula
x
Populus
tremuloides) 		5 / 9 LEU A  65
LEU A  51
GLN A  71
GLU A  50
VAL A  77
 None
 1.48A 3tmzA-3fzaA:
undetectable		 3tmzA-3fzaA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3fza GLUTAREDOXIN
(Populus
tremula
x
Populus
tremuloides) 		3 / 3 ASN A  43
PHE A  39
TYR A  94
 None
 0.80A 4u15A-3fzaA:
undetectable		 4u15A-3fzaA:
17.38