SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fze'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD207_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3fze PROTEIN STE5
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 674
PHE A 648
LEU A 767
SER A 626
 None
 1.01A 1wrlC-3fzeA:
undetectable
1wrlD-3fzeA:
undetectable		 1wrlC-3fzeA:
21.11
1wrlD-3fzeA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 3fze PROTEIN STE5
(Saccharomyces
cerevisiae) 		4 / 8 SER A 670
ASP A 666
SER A 667
ASN A 673
 None
 1.16A 2cmlD-3fzeA:
undetectable		 2cmlD-3fzeA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3fze PROTEIN STE5
(Saccharomyces
cerevisiae) 		3 / 3 THR A 619
SER A 709
LYS A 739
 None
 1.04A 3aocC-3fzeA:
undetectable		 3aocC-3fzeA:
10.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 3fze PROTEIN STE5
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 621
LEU A 627
SER A 633
LEU A 614
ILE A 616
 None
 1.12A 4x1fA-3fzeA:
undetectable		 4x1fA-3fzeA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 3fze PROTEIN STE5
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 621
LEU A 627
SER A 633
LEU A 614
ILE A 616
 None
 1.13A 4x1gA-3fzeA:
undetectable		 4x1gA-3fzeA:
20.13