SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fzu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 3fzu IMMUNOGLOBULIN IGG1
FAB, HEAVY CHAIN
(Homo
sapiens) 		5 / 12 PRO H  43
LEU H 113
LEU H  18
LEU H  88
ASP H  92
 None
 1.06A 1e7wA-3fzuH:
undetectable		 1e7wA-3fzuH:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1867_0
(FPRA)		 3fzu IMMUNOGLOBULIN IGG1
FAB, HEAVY CHAIN
(Homo
sapiens) 		4 / 4 ALA H  42
ARG H  40
GLN H  45
GLU H  48
 None
 0.90A 1lqtB-3fzuH:
undetectable		 1lqtB-3fzuH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1424_0
(FPRA)		 3fzu IMMUNOGLOBULIN IGG1
FAB, HEAVY CHAIN
(Homo
sapiens) 		4 / 4 ALA H  42
ARG H  40
GLN H  45
GLU H  48
 None
 0.93A 1lquB-3fzuH:
undetectable		 1lquB-3fzuH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 3fzu IMMUNOGLOBULIN IGG1
FAB, HEAVY CHAIN
(Homo
sapiens) 		3 / 3 ASP H 106
GLU H   6
ARG H  74
 None
 0.88A 1wopA-3fzuH:
1.6		 1wopA-3fzuH:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3fzu IMMUNOGLOBULIN IGG1
FAB, HEAVY CHAIN
(Homo
sapiens) 		4 / 7 ALA H  94
THR H  93
VAL H 114
GLU H  91
 None
 0.71A 5ecmD-3fzuH:
undetectable		 5ecmD-3fzuH:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3fzu IMMUNOGLOBULIN IGG1
FAB, HEAVY CHAIN
(Homo
sapiens) 		4 / 7 ALA H  94
THR H  93
VAL H 114
GLU H  91
 None
 0.79A 5ecoD-3fzuH:
undetectable		 5ecoD-3fzuH:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3fzu IMMUNOGLOBULIN IGG1
FAB, HEAVY CHAIN
(Homo
sapiens) 		5 / 7 PHE H 127
GLY H 123
THR H 210
VAL H 203
VAL H 212
 None
 1.40A 5ik1A-3fzuH:
undetectable		 5ik1A-3fzuH:
18.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 3fzu IMMUNOGLOBULIN IGG1
FAB, HEAVY CHAIN
(Homo
sapiens) 		3 / 3 TYR H  62
GLY H  68
THR H  71
 None
 0.16A 6cjkB-3fzuH:
25.0		 6cjkB-3fzuH:
59.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 3fzu IMMUNOGLOBULIN IGG1
FAB, HEAVY CHAIN
(Homo
sapiens) 		3 / 3 LYS H   1
SER H 100
SER H 105
 None
 0.98A 6gbfA-3fzuH:
undetectable		 6gbfA-3fzuH:
20.87