SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g01'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AQ7_B_AG2B4_1
(TRYPSIN
AERUGINOSIN 98-B)		 3g01 GRANZYME C
(Mus
musculus) 		4 / 8 HIS A  65
SER A 204
VAL A 218
GLY A 221
 None
 0.47A 1aq7A-3g01A:
31.4		 1aq7A-3g01A:
36.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.82A 2pxcA-3g01A:
undetectable		 2pxcA-3g01A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.84A 3elwA-3g01A:
undetectable		 3elwA-3g01A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.84A 3p97A-3g01A:
undetectable		 3p97A-3g01A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.83A 3p97C-3g01A:
undetectable		 3p97C-3g01A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.85A 4ctjA-3g01A:
undetectable		 4ctjA-3g01A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.82A 4ctjC-3g01A:
undetectable		 4ctjC-3g01A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.83A 4ctkA-3g01A:
undetectable		 4ctkA-3g01A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.80A 4ctkC-3g01A:
undetectable		 4ctkC-3g01A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3g01 GRANZYME C
(Mus
musculus) 		4 / 8 ASP A 105
ASN A 108
ASP A 109
GLU A 187
 None
 1.11A 4feuF-3g01A:
undetectable		 4feuF-3g01A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3g01 GRANZYME C
(Mus
musculus) 		4 / 7 ASP A 105
ASN A 108
ASP A 109
GLU A 187
 None
 1.12A 4fevD-3g01A:
undetectable		 4fevD-3g01A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3g01 GRANZYME C
(Mus
musculus) 		4 / 7 ASP A 105
ASN A 108
ASP A 109
GLU A 187
 None
 1.12A 4fevF-3g01A:
undetectable		 4fevF-3g01A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3g01 GRANZYME C
(Mus
musculus) 		4 / 8 ASP A 105
ASN A 108
ASP A 109
GLU A 187
 None
 1.09A 4fewD-3g01A:
undetectable		 4fewD-3g01A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3g01 GRANZYME C
(Mus
musculus) 		4 / 8 ASP A 105
ASN A 108
ASP A 109
GLU A 187
 None
 1.09A 4fewF-3g01A:
undetectable		 4fewF-3g01A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3g01 GRANZYME C
(Mus
musculus) 		4 / 8 ASP A 105
ASN A 108
ASP A 109
GLU A 187
 None
 1.10A 4gkhF-3g01A:
undetectable		 4gkhF-3g01A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3g01 GRANZYME C
(Mus
musculus) 		4 / 7 ASP A 105
ASN A 108
ASP A 109
GLU A 187
 None
 1.11A 4gkhG-3g01A:
undetectable		 4gkhG-3g01A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3g01 GRANZYME C
(Mus
musculus) 		4 / 8 ASP A 105
ASN A 108
ASP A 109
GLU A 187
 None
 1.11A 4gkiA-3g01A:
undetectable		 4gkiA-3g01A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJQ_A_27RA401_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3g01 GRANZYME C
(Mus
musculus) 		4 / 5 ARG A  32
TYR A  34
PRO A 207
VAL A 218
 None
 1.48A 4mjqA-3g01A:
undetectable		 4mjqA-3g01A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 3g01 GRANZYME C
(Mus
musculus) 		4 / 4 LEU A 130
SER A 239
LEU A 235
LEU A  61
 None
 1.11A 4n09A-3g01A:
undetectable		 4n09A-3g01A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 VAL A 234
GLY A  52
ILE A 110
LEU A 112
LEU A  54
 None
 0.90A 4qdjA-3g01A:
undetectable		 4qdjA-3g01A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.82A 5e9qA-3g01A:
undetectable		 5e9qA-3g01A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.81A 5e9qC-3g01A:
undetectable		 5e9qC-3g01A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.85A 5ec8A-3g01A:
undetectable		 5ec8A-3g01A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.82A 5ec8C-3g01A:
undetectable		 5ec8C-3g01A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.84A 5ehgA-3g01A:
undetectable		 5ehgA-3g01A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.81A 5ehgC-3g01A:
undetectable		 5ehgC-3g01A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.84A 5eifA-3g01A:
undetectable		 5eifA-3g01A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.81A 5eifC-3g01A:
undetectable		 5eifC-3g01A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.80A 5eiwC-3g01A:
undetectable		 5eiwC-3g01A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.83A 5ekxB-3g01A:
undetectable		 5ekxB-3g01A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.88A 5ikmA-3g01A:
undetectable		 5ikmA-3g01A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3g01 GRANZYME C
(Mus
musculus) 		3 / 3 VAL A 230
SER A 107
MET A 111
 None
 0.94A 5ikqA-3g01A:
undetectable		 5ikqA-3g01A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 206
PRO A 207
VAL A 145
PHE A  53
LEU A  61
 None
 1.14A 5jo9A-3g01A:
undetectable		 5jo9A-3g01A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.86A 5kqrA-3g01A:
undetectable		 5kqrA-3g01A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.86A 5kqsA-3g01A:
undetectable		 5kqsA-3g01A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.84A 5m5bA-3g01A:
undetectable		 5m5bA-3g01A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.83A 5njvA-3g01A:
undetectable		 5njvA-3g01A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.85A 5njvB-3g01A:
undetectable		 5njvB-3g01A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_C_SAMC301_0
(NS5)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.90A 5njvC-3g01A:
undetectable		 5njvC-3g01A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.84A 5vimA-3g01A:
undetectable		 5vimA-3g01A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.85A 5vimB-3g01A:
undetectable		 5vimB-3g01A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.78A 5wz1B-3g01A:
undetectable		 5wz1B-3g01A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.84A 5wz2A-3g01A:
undetectable		 5wz2A-3g01A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.84A 5wz2B-3g01A:
undetectable		 5wz2B-3g01A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 3g01 GRANZYME C
(Mus
musculus) 		5 / 12 GLY A 149
GLY A  52
GLY A 206
GLY A 202
VAL A  60
 None
 0.88A 5wz2C-3g01A:
undetectable		 5wz2C-3g01A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3g01 GRANZYME C
(Mus
musculus) 		3 / 3 TYR A 220
ARG A 106
THR A 232
 None
 0.87A 5z84J-3g01A:
undetectable		 5z84J-3g01A:
12.44