SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g06'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 10 GLY A 616
MET A 619
LEU A 622
THR A 659
LEU A 658
None
1.38A 1a8uA-3g06A:
undetectable
1a8uA-3g06A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AKE_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 12 GLY A 623
GLN A 590
ILE A 642
GLN A 649
PHE A 586
None
1.05A 2akeA-3g06A:
undetectable
2akeA-3g06A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA601_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 12 GLY A 623
GLN A 590
ILE A 642
GLN A 649
PHE A 586
None
1.10A 2azxA-3g06A:
undetectable
2azxA-3g06A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_B_TRPB603_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 12 GLY A 623
GLN A 590
ILE A 642
GLN A 649
PHE A 586
None
1.07A 2azxB-3g06A:
undetectable
2azxB-3g06A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 11 LEU A 264
LEU A 267
SER A 256
LEU A 257
LEU A 260
None
1.07A 2ceoA-3g06A:
undetectable
2ceoA-3g06A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 11 LEU A 304
LEU A 307
SER A 296
LEU A 297
LEU A 300
None
1.09A 2ceoA-3g06A:
undetectable
2ceoA-3g06A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 11 LEU A 404
LEU A 407
SER A 396
LEU A 397
LEU A 400
None
1.10A 2ceoA-3g06A:
undetectable
2ceoA-3g06A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 11 LEU A 424
LEU A 427
SER A 416
LEU A 417
LEU A 420
None
1.07A 2ceoA-3g06A:
undetectable
2ceoA-3g06A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 10 ALA A 711
LEU A 609
LEU A 777
LEU A 707
ARG A 709
None
1.15A 2ceoB-3g06A:
undetectable
2ceoB-3g06A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR2_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 11 GLY A 623
GLN A 590
ILE A 642
GLN A 649
PHE A 586
None
1.02A 2dr2A-3g06A:
undetectable
2dr2A-3g06A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 12 LEU A 344
LEU A 364
LEU A 384
LEU A 397
PRO A 398
None
1.13A 2pnjA-3g06A:
undetectable
2pnjA-3g06A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 11 LEU A 257
LEU A 237
LEU A 216
ILE A 269
THR A 214
None
1.31A 2qd3A-3g06A:
undetectable
2qd3A-3g06A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 10 ALA A 711
LEU A 609
LEU A 777
LEU A 707
ARG A 709
None
1.19A 2riwA-3g06A:
undetectable
2riwB-3g06A:
undetectable
2riwA-3g06A:
20.51
2riwB-3g06A:
6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 10 ALA A 711
LEU A 609
LEU A 777
LEU A 707
ARG A 709
None
1.07A 2xn7A-3g06A:
undetectable
2xn7B-3g06A:
undetectable
2xn7A-3g06A:
21.02
2xn7B-3g06A:
6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 10 LEU A 264
LEU A 267
SER A 256
LEU A 257
LEU A 260
None
1.10A 2xn7A-3g06A:
undetectable
2xn7B-3g06A:
undetectable
2xn7A-3g06A:
21.02
2xn7B-3g06A:
6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 10 LEU A 344
LEU A 347
SER A 336
LEU A 337
LEU A 340
None
1.14A 2xn7A-3g06A:
undetectable
2xn7B-3g06A:
undetectable
2xn7A-3g06A:
21.02
2xn7B-3g06A:
6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 10 LEU A 364
LEU A 367
SER A 356
LEU A 357
LEU A 360
None
1.13A 2xn7A-3g06A:
undetectable
2xn7B-3g06A:
undetectable
2xn7A-3g06A:
21.02
2xn7B-3g06A:
6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
4 / 5 PHE A 587
PHE A 532
LEU A 536
PHE A 548
None
1.37A 3abmP-3g06A:
undetectable
3abmW-3g06A:
undetectable
3abmP-3g06A:
19.48
3abmW-3g06A:
6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 7 THR A 246
GLU A 248
VAL A 228
THR A 226
VAL A 205
None
1.11A 3em0B-3g06A:
undetectable
3em0B-3g06A:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
4 / 8 GLU A 453
ASN A 455
ASN A 451
ILE A 479
None
1.13A 3kp6A-3g06A:
4.0
3kp6B-3g06A:
undetectable
3kp6A-3g06A:
12.56
3kp6B-3g06A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
3 / 3 GLN A 604
THR A 615
ASN A 599
None
0.89A 3v4tE-3g06A:
undetectable
3v4tE-3g06A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
3 / 3 GLU A 750
GLY A 745
SER A 734
None
0.62A 4b53B-3g06A:
undetectable
4b53B-3g06A:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 12 VAL A 191
LEU A 206
LEU A 216
THR A 215
PRO A 238
None
1.08A 4k0zA-3g06A:
undetectable
4k0zA-3g06A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 12 ALA A 681
LEU A 678
ALA A 647
VAL A 644
ALA A 629
None
1.27A 4x1iB-3g06A:
undetectable
4x1iB-3g06A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
4 / 4 ASN A 332
SER A 308
ALA A 329
VAL A 349
None
1.40A 4x1kC-3g06A:
undetectable
4x1kC-3g06A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
4 / 7 VAL A 228
ILE A 229
LEU A 277
LEU A 257
None
0.94A 4xo7A-3g06A:
undetectable
4xo7A-3g06A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 11 LEU A 314
LEU A 260
LEU A 274
LEU A 294
LEU A 257
None
1.01A 4zowA-3g06A:
undetectable
4zowA-3g06A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 11 LEU A 374
LEU A 320
LEU A 334
LEU A 354
LEU A 317
None
1.05A 4zowA-3g06A:
undetectable
4zowA-3g06A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 11 LEU A 465
LEU A 457
LEU A 407
LEU A 444
LEU A 424
None
1.03A 4zowA-3g06A:
undetectable
4zowA-3g06A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 12 ILE A 552
VAL A 584
PHE A 548
THR A 539
MET A 591
None
1.12A 5byjA-3g06A:
undetectable
5byjA-3g06A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 12 ILE A 552
VAL A 584
PHE A 548
THR A 539
MET A 591
None
1.08A 5bykA-3g06A:
undetectable
5bykA-3g06A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
4 / 7 VAL A 349
LEU A 354
ALA A 329
LEU A 344
None
0.56A 5jq7A-3g06A:
undetectable
5jq7A-3g06A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
4 / 7 VAL A 389
LEU A 394
ALA A 369
LEU A 384
None
0.59A 5jq7A-3g06A:
undetectable
5jq7A-3g06A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
4 / 4 ASN A 372
LEU A 374
SER A 390
LEU A 387
None
1.10A 5kb5A-3g06A:
undetectable
5kb5A-3g06A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 10 ILE A 552
VAL A 584
PHE A 548
THR A 539
MET A 591
None
1.05A 6b4yA-3g06A:
undetectable
6b4yA-3g06A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 10 VAL A 309
LEU A 314
LEU A 334
LEU A 300
LEU A 297
None
0.92A 6f5uA-3g06A:
undetectable
6f5uB-3g06A:
undetectable
6f5uA-3g06A:
9.43
6f5uB-3g06A:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 10 VAL A 349
LEU A 354
LEU A 374
LEU A 340
LEU A 337
None
0.91A 6f5uA-3g06A:
undetectable
6f5uB-3g06A:
undetectable
6f5uA-3g06A:
9.43
6f5uB-3g06A:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 10 VAL A 389
LEU A 394
LEU A 414
LEU A 380
LEU A 377
None
0.89A 6f5uA-3g06A:
undetectable
6f5uB-3g06A:
undetectable
6f5uA-3g06A:
9.43
6f5uB-3g06A:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 10 VAL A 409
LEU A 414
LEU A 434
LEU A 400
LEU A 397
None
0.87A 6f5uA-3g06A:
undetectable
6f5uB-3g06A:
undetectable
6f5uA-3g06A:
9.43
6f5uB-3g06A:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
5 / 10 VAL A 429
LEU A 434
LEU A 457
LEU A 420
LEU A 417
None
0.95A 6f5uA-3g06A:
undetectable
6f5uB-3g06A:
undetectable
6f5uA-3g06A:
9.43
6f5uB-3g06A:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
4 / 7 LEU A 257
LEU A 247
LEU A 244
LEU A 216
None
0.60A 6g9bA-3g06A:
undetectable
6g9bB-3g06A:
undetectable
6g9bA-3g06A:
9.43
6g9bB-3g06A:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
4 / 7 LEU A 277
LEU A 267
LEU A 264
LEU A 237
None
0.73A 6g9bA-3g06A:
undetectable
6g9bB-3g06A:
undetectable
6g9bA-3g06A:
9.43
6g9bB-3g06A:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica)
4 / 7 ASP A 669
GLU A 643
ASP A 582
GLU A 581
None
1.12A 6mn5E-3g06A:
undetectable
6mn5E-3g06A:
7.93