SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g0m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1866_0
(FPRA)		 3g0m CYSTEINE
DESULFURATION
PROTEIN SUFE
(Salmonella
enterica) 		4 / 4 ARG A  60
LEU A  37
ASN A  38
VAL A  58
 None
 1.37A 1lqtA-3g0mA:
undetectable		 1lqtA-3g0mA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1875_0
(FPRA)		 3g0m CYSTEINE
DESULFURATION
PROTEIN SUFE
(Salmonella
enterica) 		4 / 4 ARG A  60
LEU A  37
ASN A  38
VAL A  58
 None
 1.37A 1lqtB-3g0mA:
undetectable		 1lqtB-3g0mA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1423_0
(FPRA)		 3g0m CYSTEINE
DESULFURATION
PROTEIN SUFE
(Salmonella
enterica) 		4 / 4 ARG A  60
LEU A  37
ASN A  38
VAL A  58
 None
 1.37A 1lquA-3g0mA:
undetectable		 1lquA-3g0mA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1432_0
(FPRA)		 3g0m CYSTEINE
DESULFURATION
PROTEIN SUFE
(Salmonella
enterica) 		4 / 4 ARG A  60
LEU A  37
ASN A  38
VAL A  58
 None
 1.36A 1lquB-3g0mA:
undetectable		 1lquB-3g0mA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 3g0m CYSTEINE
DESULFURATION
PROTEIN SUFE
(Salmonella
enterica) 		3 / 3 PHE A  14
LEU A  30
MET A   1
 None
 0.87A 1mx1D-3g0mA:
undetectable		 1mx1D-3g0mA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KI5_B_AC2B2_1
(PROTEIN (THYMIDINE
KINASE))		 3g0m CYSTEINE
DESULFURATION
PROTEIN SUFE
(Salmonella
enterica) 		5 / 12 ILE A  77
ILE A  28
TYR A  24
GLN A  32
ARG A 119
 EDO  A 202 (-3.9A)
None
None
None
EDO  A 202 (-4.2A)
 1.41A 2ki5B-3g0mA:
0.0		 2ki5B-3g0mA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3g0m CYSTEINE
DESULFURATION
PROTEIN SUFE
(Salmonella
enterica) 		4 / 6 VAL A 102
LEU A  34
ILE A  77
LEU A  88
 None
None
EDO  A 202 (-3.9A)
None
 0.97A 3kk6A-3g0mA:
undetectable		 3kk6A-3g0mA:
13.51