SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g0t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		5 / 11 ASN A   2
MET A   1
GLY A   0
THR A  43
GLY A 393
 None
 1.48A 1jr1A-3g0tA:
undetectable		 1jr1A-3g0tA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		3 / 3 ARG A 344
SER A 233
TYR A 232
 None
 0.75A 1x70A-3g0tA:
undetectable		 1x70A-3g0tA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 8 VAL A 244
ASP A 200
TYR A 251
TYR A 187
 None
 1.00A 1z2bB-3g0tA:
undetectable		 1z2bB-3g0tA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		5 / 12 LEU A 432
ASN A 353
GLY A 354
MET A 380
MET A 394
 None
 1.45A 2q7lA-3g0tA:
undetectable		 2q7lA-3g0tA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 8 THR A 194
PRO A 193
ALA A 409
PRO A 140
 None
 0.99A 2v32A-3g0tA:
undetectable
2v32B-3g0tA:
undetectable		 2v32A-3g0tA:
19.86
2v32B-3g0tA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 8 PRO A 140
THR A 194
PRO A 193
ALA A 409
 None
 0.98A 2v32A-3g0tA:
undetectable
2v32B-3g0tA:
undetectable		 2v32A-3g0tA:
19.86
2v32B-3g0tA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 8 THR A 194
PRO A 193
ALA A 409
PRO A 140
 None
 1.05A 2v41G-3g0tA:
undetectable
2v41H-3g0tA:
undetectable		 2v41G-3g0tA:
19.86
2v41H-3g0tA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 8 ILE A  60
PRO A  58
GLY A  61
SER A 257
 None
 0.75A 3lslA-3g0tA:
undetectable
3lslD-3g0tA:
undetectable		 3lslA-3g0tA:
20.50
3lslD-3g0tA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		3 / 3 ASP A 220
ASN A 145
SER A 256
 LLP  A 259 ( 2.8A)
None
LLP  A 259 ( 2.5A)
 0.88A 3lslA-3g0tA:
undetectable
3lslD-3g0tA:
0.7		 3lslA-3g0tA:
20.50
3lslD-3g0tA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 8 SER A 257
ILE A  60
PRO A  58
GLY A  61
 None
 0.78A 3lslA-3g0tA:
undetectable
3lslD-3g0tA:
undetectable		 3lslA-3g0tA:
20.50
3lslD-3g0tA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 4 PHE A  93
TYR A 240
ILE A 273
LEU A 271
 None
NA  A 437 ( 4.6A)
None
None
 1.39A 3sudA-3g0tA:
undetectable		 3sudA-3g0tA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 5 PHE A  93
TYR A 240
ILE A 273
LEU A 271
 None
NA  A 437 ( 4.6A)
None
None
 1.33A 3sueC-3g0tA:
undetectable		 3sueC-3g0tA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 8 TYR A 377
VAL A 375
MET A  48
ILE A 412
 None
 1.00A 4a97G-3g0tA:
undetectable		 4a97G-3g0tA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 7 PHE A 261
VAL A 336
PHE A  93
GLY A 225
 None
 0.85A 4ejjB-3g0tA:
undetectable		 4ejjB-3g0tA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		5 / 12 GLY A 112
GLY A 116
VAL A 111
THR A 110
SER A 256
 LLP  A 259 ( 3.5A)
None
None
None
LLP  A 259 ( 2.5A)
 1.16A 4f84A-3g0tA:
3.4		 4f84A-3g0tA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_A_SAMA401_0
(METHYLTRANSFERASE
MPPJ)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		5 / 12 GLY A 134
ILE A 216
ALA A 124
ALA A 210
ASP A 214
 EDO  A 443 (-3.7A)
None
None
None
None
 1.23A 4kicA-3g0tA:
3.5		 4kicA-3g0tA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKN_B_KANB403_1
(L-LACTATE
DEHYDROGENASE A
CHAIN)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		5 / 9 VAL A 123
ARG A 293
ARG A 105
ILE A 273
ILE A 252
 None
 1.30A 4oknB-3g0tA:
2.4		 4oknB-3g0tA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		5 / 12 GLY A 116
GLN A 115
VAL A 108
LEU A 298
SER A 307
 None
 1.12A 4pd5A-3g0tA:
undetectable		 4pd5A-3g0tA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		5 / 12 GLY A 116
GLN A 115
VAL A 108
LEU A 298
SER A 307
 None
 1.13A 4pd9A-3g0tA:
undetectable		 4pd9A-3g0tA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		3 / 3 MET A 114
GLN A 266
TYR A 263
 None
 1.02A 4udcA-3g0tA:
undetectable		 4udcA-3g0tA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 8 ILE A 218
LEU A 253
SER A 243
ALA A 106
 None
 0.79A 4wboB-3g0tA:
undetectable		 4wboB-3g0tA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 8 LEU A 277
LEU A 253
SER A 243
ALA A 106
 EDO  A 441 (-4.1A)
None
None
None
 0.73A 4wboB-3g0tA:
undetectable		 4wboB-3g0tA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		5 / 12 VAL A  98
ILE A 218
ILE A 216
ASN A 250
SER A 120
 None
None
None
EDO  A 441 (-3.4A)
None
 1.19A 4xueA-3g0tA:
3.3		 4xueA-3g0tA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 5 ILE A 185
ILE A 218
TYR A 187
GLU A 219
 None
 1.05A 4zzcE-3g0tA:
undetectable		 4zzcE-3g0tA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 5 SER A 288
ARG A 293
GLY A 295
GLU A 279
 None
 1.04A 5cdqA-3g0tA:
undetectable
5cdqB-3g0tA:
undetectable
5cdqC-3g0tA:
undetectable		 5cdqA-3g0tA:
22.63
5cdqB-3g0tA:
18.30
5cdqC-3g0tA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 5 SER A 288
ARG A 293
GLY A 295
GLU A 279
 None
 1.05A 5cdqR-3g0tA:
undetectable
5cdqS-3g0tA:
undetectable
5cdqT-3g0tA:
undetectable		 5cdqR-3g0tA:
22.63
5cdqS-3g0tA:
18.30
5cdqT-3g0tA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		3 / 3 PRO A  78
ILE A  66
SER A 308
 None
 0.74A 5fsaA-3g0tA:
undetectable		 5fsaA-3g0tA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 4 CYH A 395
PHE A 389
ILE A  10
GLY A 393
 None
 1.38A 5hesB-3g0tA:
undetectable		 5hesB-3g0tA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 7 LEU A 298
ALA A 124
THR A 127
LEU A 285
 None
 0.81A 5te8A-3g0tA:
undetectable		 5te8A-3g0tA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3g0t PUTATIVE
AMINOTRANSFERASE
(Porphyromonas
gingivalis) 		5 / 12 ASN A 143
ILE A 151
ILE A 218
PHE A 137
PHE A 156
 None
 1.19A 6j20A-3g0tA:
undetectable		 6j20A-3g0tA:
21.06