SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g12'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3g12 PUTATIVE
LACTOYLGLUTATHIONE
LYASE
(Bdellovibrio
bacteriovorus) 		4 / 6 ASP A 107
LEU A 106
VAL A 105
ILE A 104
 None
 0.93A 1s9qA-3g12A:
undetectable		 1s9qA-3g12A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 3g12 PUTATIVE
LACTOYLGLUTATHIONE
LYASE
(Bdellovibrio
bacteriovorus) 		4 / 8 GLY A  20
ASP A 107
TYR A  22
THR A  12
 None
 1.00A 2aouA-3g12A:
undetectable		 2aouA-3g12A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 3g12 PUTATIVE
LACTOYLGLUTATHIONE
LYASE
(Bdellovibrio
bacteriovorus) 		4 / 7 GLY A  20
ASP A 107
TYR A  22
THR A  12
 None
 1.00A 2aouB-3g12A:
undetectable		 2aouB-3g12A:
18.86