SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g1b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 3g1b ATP-DEPENDENT CLP
PROTEASE ADAPTER
PROTEIN CLPS
(Caulobacter
vibrioides) 		4 / 6 ASN A  47
ASP A  48
THR A  51
PRO A  52
 None
 0.83A 1n4fA-3g1bA:
undetectable		 1n4fA-3g1bA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3g1b ATP-DEPENDENT CLP
PROTEASE ADAPTER
PROTEIN CLPS
(Caulobacter
vibrioides) 		3 / 3 ASP A 103
THR A  51
PRO A  52
 None
 0.50A 2pynB-3g1bA:
undetectable		 2pynB-3g1bA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 3g1b ATP-DEPENDENT CLP
PROTEASE ADAPTER
PROTEIN CLPS
(Caulobacter
vibrioides) 		3 / 3 ASP A 103
THR A  51
PRO A  52
 None
 0.44A 2q64B-3g1bA:
undetectable		 2q64B-3g1bA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3g1b ATP-DEPENDENT CLP
PROTEASE ADAPTER
PROTEIN CLPS
(Caulobacter
vibrioides) 		3 / 3 ASP A 103
THR A  51
PRO A  52
 None
 0.53A 2qakB-3g1bA:
undetectable		 2qakB-3g1bA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 3g1b ATP-DEPENDENT CLP
PROTEASE ADAPTER
PROTEIN CLPS
(Caulobacter
vibrioides) 		3 / 3 ASP A 103
THR A  51
PRO A  52
 None
 0.39A 3tkgD-3g1bA:
undetectable		 3tkgD-3g1bA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 3g1b ATP-DEPENDENT CLP
PROTEASE ADAPTER
PROTEIN CLPS
(Caulobacter
vibrioides) 		5 / 9 TYR A  89
VAL A 101
ALA A  99
GLY A  87
PHE A  64
 None
 1.40A 4mmeA-3g1bA:
undetectable		 4mmeA-3g1bA:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 3g1b ATP-DEPENDENT CLP
PROTEASE ADAPTER
PROTEIN CLPS
(Caulobacter
vibrioides) 		5 / 9 TYR A  89
VAL A 101
ALA A  99
GLY A  87
PHE A  64
 None
 1.24A 4mmeB-3g1bA:
undetectable		 4mmeB-3g1bA:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 3g1b ATP-DEPENDENT CLP
PROTEASE ADAPTER
PROTEIN CLPS
(Caulobacter
vibrioides) 		5 / 9 TYR A  89
VAL A 101
ALA A  99
GLY A  87
PHE A  64
 None
 1.38A 4mmfA-3g1bA:
undetectable		 4mmfA-3g1bA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 3g1b ATP-DEPENDENT CLP
PROTEASE ADAPTER
PROTEIN CLPS
(Caulobacter
vibrioides) 		5 / 9 TYR A  89
VAL A 101
ALA A  99
GLY A  87
PHE A  64
 None
 1.36A 4mmfB-3g1bA:
undetectable		 4mmfB-3g1bA:
7.65