SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g1p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		3 / 3 MET A 186
LEU A 162
SER A 163
 None
 0.60A 1ee2A-3g1pA:
undetectable		 1ee2A-3g1pA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		4 / 5 ASP A 164
HIS A 143
HIS A 222
HIS A 200
 MN  A 401 (-2.1A)
MN  A 400 ( 3.4A)
MN  A 401 (-3.7A)
MLT  A 500 (-4.1A)
 1.18A 1ei6A-3g1pA:
undetectable		 1ei6A-3g1pA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		3 / 3 ASP A  80
HIS A 143
ASP A 187
 MLT  A 500 ( 2.8A)
MN  A 400 ( 3.4A)
None
 0.89A 1nw5A-3g1pA:
undetectable		 1nw5A-3g1pA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		3 / 3 ASP A 164
HIS A 222
HIS A 200
 MN  A 401 (-2.1A)
MN  A 401 (-3.7A)
MLT  A 500 (-4.1A)
 0.59A 1oe1A-3g1pA:
undetectable		 1oe1A-3g1pA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		3 / 3 ASP A 164
HIS A 222
HIS A 200
 MN  A 401 (-2.1A)
MN  A 401 (-3.7A)
MLT  A 500 (-4.1A)
 0.58A 1oe3A-3g1pA:
undetectable		 1oe3A-3g1pA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		5 / 12 ASP A 103
HIS A  81
HIS A  76
ASP A  80
HIS A  78
 None
MN  A 401 (-3.5A)
MN  A 400 ( 3.4A)
MLT  A 500 ( 2.8A)
MN  A 400 ( 3.3A)
 1.43A 1t69A-3g1pA:
undetectable		 1t69A-3g1pA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		5 / 11 ASP A  80
HIS A  81
HIS A 143
ASP A 164
HIS A 222
 MLT  A 500 ( 2.8A)
MN  A 401 (-3.5A)
MN  A 400 ( 3.4A)
MN  A 401 (-2.1A)
MN  A 401 (-3.7A)
 0.96A 2q0jB-3g1pA:
10.5		 2q0jB-3g1pA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		3 / 3 GLN A  38
THR A   6
TRP A  64
 None
 0.97A 2rctA-3g1pA:
undetectable		 2rctA-3g1pA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		5 / 12 LEU A  88
GLY A  84
ALA A  55
SER A  65
GLY A  67
 None
 1.29A 2vmyB-3g1pA:
undetectable		 2vmyB-3g1pA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		3 / 3 ASP A 164
HIS A 222
HIS A 200
 MN  A 401 (-2.1A)
MN  A 401 (-3.7A)
MLT  A 500 (-4.1A)
 0.60A 2xxgA-3g1pA:
undetectable		 2xxgA-3g1pA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		3 / 3 ASP A 164
HIS A 222
HIS A 200
 MN  A 401 (-2.1A)
MN  A 401 (-3.7A)
MLT  A 500 (-4.1A)
 0.64A 2xxgC-3g1pA:
undetectable		 2xxgC-3g1pA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		5 / 6 ASP A 103
HIS A  81
HIS A  76
ASP A  80
HIS A  78
 None
MN  A 401 (-3.5A)
MN  A 400 ( 3.4A)
MLT  A 500 ( 2.8A)
MN  A 400 ( 3.3A)
 1.36A 3c0zC-3g1pA:
undetectable		 3c0zC-3g1pA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1D_B_X8ZB350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		5 / 10 HIS A  76
HIS A  78
ASP A  80
HIS A 143
HIS A 222
 MN  A 400 ( 3.4A)
MN  A 400 ( 3.3A)
MLT  A 500 ( 2.8A)
MN  A 400 ( 3.4A)
MN  A 401 (-3.7A)
 0.88A 4c1dB-3g1pA:
9.4		 4c1dB-3g1pA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1D_B_X8ZB350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		5 / 10 HIS A  76
HIS A  78
HIS A 143
ASN A 199
HIS A 222
 MN  A 400 ( 3.4A)
MN  A 400 ( 3.3A)
MN  A 400 ( 3.4A)
None
MN  A 401 (-3.7A)
 1.06A 4c1dB-3g1pA:
9.4		 4c1dB-3g1pA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		5 / 11 HIS A  76
HIS A  78
ASP A  80
ASN A 199
HIS A 222
 MN  A 400 ( 3.4A)
MN  A 400 ( 3.3A)
MLT  A 500 ( 2.8A)
None
MN  A 401 (-3.7A)
 1.13A 4c1fA-3g1pA:
2.9
4c1fB-3g1pA:
7.3		 4c1fA-3g1pA:
19.56
4c1fB-3g1pA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		5 / 11 HIS A  76
HIS A  78
ASP A  80
HIS A 143
HIS A 222
 MN  A 400 ( 3.4A)
MN  A 400 ( 3.3A)
MLT  A 500 ( 2.8A)
MN  A 400 ( 3.4A)
MN  A 401 (-3.7A)
 0.88A 4c1fA-3g1pA:
2.9
4c1fB-3g1pA:
7.3		 4c1fA-3g1pA:
19.56
4c1fB-3g1pA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		4 / 8 LEU A   7
SER A  41
TRP A 161
ASP A 187
 None
 1.10A 4drjB-3g1pA:
undetectable		 4drjB-3g1pA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		4 / 8 HIS A  78
ASP A  80
HIS A 143
HIS A 222
 MN  A 400 ( 3.3A)
MLT  A 500 ( 2.8A)
MN  A 400 ( 3.4A)
MN  A 401 (-3.7A)
 0.87A 4exsB-3g1pA:
10.0		 4exsB-3g1pA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_A_WJZA304_0
(BETA-LACTAMASE NDM-1)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		4 / 8 HIS A  78
ASP A  80
HIS A 143
HIS A 222
 MN  A 400 ( 3.3A)
MLT  A 500 ( 2.8A)
MN  A 400 ( 3.4A)
MN  A 401 (-3.7A)
 0.84A 5a5zA-3g1pA:
9.7		 5a5zA-3g1pA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		6 / 11 HIS A  76
HIS A  78
ASP A  80
HIS A  81
HIS A 143
HIS A 222
 MN  A 400 ( 3.4A)
MN  A 400 ( 3.3A)
MLT  A 500 ( 2.8A)
MN  A 401 (-3.5A)
MN  A 400 ( 3.4A)
MN  A 401 (-3.7A)
 0.60A 5ayaA-3g1pA:
10.3		 5ayaA-3g1pA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		5 / 11 ALA A  18
ALA A  13
GLY A  12
ASP A 228
LEU A 231
 ZN  A 300 ( 4.6A)
MLT  A 500 ( 3.8A)
None
None
None
 1.13A 5lf7V-3g1pA:
undetectable
5lf7W-3g1pA:
undetectable		 5lf7V-3g1pA:
20.46
5lf7W-3g1pA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		4 / 8 ASP A 164
ASP A 187
HIS A 222
ARG A 198
 MN  A 401 (-2.1A)
None
MN  A 401 (-3.7A)
None
 0.92A 5nekB-3g1pA:
undetectable		 5nekB-3g1pA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		4 / 8 ASP A 164
HIS A 143
HIS A  76
HIS A 222
 MN  A 401 (-2.1A)
MN  A 400 ( 3.4A)
MN  A 400 ( 3.4A)
MN  A 401 (-3.7A)
 0.92A 5nekD-3g1pA:
undetectable		 5nekD-3g1pA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		6 / 10 HIS A  76
HIS A  78
HIS A  81
HIS A 143
ASP A 164
HIS A 200
 MN  A 400 ( 3.4A)
MN  A 400 ( 3.3A)
MN  A 401 (-3.5A)
MN  A 400 ( 3.4A)
MN  A 401 (-2.1A)
MLT  A 500 (-4.1A)
 0.36A 5nzwA-3g1pA:
12.7		 5nzwA-3g1pA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		5 / 10 HIS A 143
HIS A  76
HIS A 200
ASP A 164
HIS A 222
 MN  A 400 ( 3.4A)
MN  A 400 ( 3.4A)
MLT  A 500 (-4.1A)
MN  A 401 (-2.1A)
MN  A 401 (-3.7A)
 0.93A 5nzwA-3g1pA:
12.7		 5nzwA-3g1pA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		3 / 3 HIS A  81
ASP A 164
HIS A 222
 MN  A 401 (-3.5A)
MN  A 401 (-2.1A)
MN  A 401 (-3.7A)
 0.67A 5oexA-3g1pA:
undetectable		 5oexA-3g1pA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		3 / 3 HIS A 143
HIS A 200
HIS A 222
 MN  A 400 ( 3.4A)
MLT  A 500 (-4.1A)
MN  A 401 (-3.7A)
 0.99A 5oexA-3g1pA:
undetectable		 5oexA-3g1pA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		3 / 3 HIS A  81
ASP A 164
HIS A 222
 MN  A 401 (-3.5A)
MN  A 401 (-2.1A)
MN  A 401 (-3.7A)
 0.69A 5oexB-3g1pA:
undetectable		 5oexB-3g1pA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		3 / 3 HIS A  81
ASP A 164
HIS A 222
 MN  A 401 (-3.5A)
MN  A 401 (-2.1A)
MN  A 401 (-3.7A)
 0.69A 5oexC-3g1pA:
undetectable		 5oexC-3g1pA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		3 / 3 HIS A  81
ASP A 164
HIS A 222
 MN  A 401 (-3.5A)
MN  A 401 (-2.1A)
MN  A 401 (-3.7A)
 0.68A 5oexD-3g1pA:
undetectable		 5oexD-3g1pA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		4 / 8 HIS A  78
ASP A  80
HIS A 143
HIS A 222
 MN  A 400 ( 3.3A)
MLT  A 500 ( 2.8A)
MN  A 400 ( 3.4A)
MN  A 401 (-3.7A)
 0.91A 5zj8A-3g1pA:
9.7		 5zj8A-3g1pA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		5 / 12 SER A  41
PHE A 244
GLY A 246
ILE A  53
LEU A   5
 None
 1.15A 6dwnC-3g1pA:
undetectable		 6dwnC-3g1pA:
15.73