SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g25'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 9 ALA A 443
GLY A 240
ILE A  78
ILE A  73
ILE A   5
 None
 0.86A 1hshB-3g25A:
undetectable		 1hshB-3g25A:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 ALA A  99
VAL A  87
TRP A  88
 None
 0.82A 1jo3A-3g25A:
undetectable		 1jo3A-3g25A:
3.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 ALA A  99
VAL A  87
TRP A  88
 None
 0.82A 1jo3B-3g25A:
undetectable		 1jo3B-3g25A:
3.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 ALA A  99
VAL A  87
TRP A  88
 None
 0.93A 1nrmA-3g25A:
undetectable		 1nrmA-3g25A:
3.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 ALA A  99
VAL A  87
TRP A  88
 None
 0.93A 1nrmB-3g25A:
undetectable		 1nrmB-3g25A:
3.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 ALA A  99
VAL A  87
TRP A  88
 None
 0.79A 1nt6A-3g25A:
undetectable		 1nt6A-3g25A:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 ALA A  99
VAL A  87
TRP A  88
 None
 0.79A 1nt6B-3g25A:
undetectable		 1nt6B-3g25A:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 12 LEU A 285
THR A 287
LEU A 271
ILE A 400
GLY A 258
 None
 1.00A 1qknA-3g25A:
undetectable		 1qknA-3g25A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AKE_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 12 THR A 266
GLY A 265
GLY A 409
THR A 263
GLN A 245
 PO4  A 502 ( 3.4A)
PO4  A 502 (-3.3A)
None
None
GOL  A 499 (-4.0A)
 1.23A 2akeA-3g25A:
undetectable		 2akeA-3g25A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		4 / 5 ASP A 294
GLY A 447
ALA A 218
ILE A 293
 None
 0.92A 2aofA-3g25A:
undetectable		 2aofA-3g25A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA601_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 12 THR A 266
GLY A 265
GLY A 409
THR A 263
GLN A 245
 PO4  A 502 ( 3.4A)
PO4  A 502 (-3.3A)
None
None
GOL  A 499 (-4.0A)
 1.27A 2azxA-3g25A:
undetectable		 2azxA-3g25A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_B_TRPB603_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 12 THR A 266
GLY A 265
GLY A 409
THR A 263
GLN A 245
 PO4  A 502 ( 3.4A)
PO4  A 502 (-3.3A)
None
None
GOL  A 499 (-4.0A)
 1.23A 2azxB-3g25A:
undetectable		 2azxB-3g25A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 12 GLN A 493
ALA A 359
GLN A 108
LEU A 131
LEU A 350
 None
 1.30A 2nv4B-3g25A:
undetectable		 2nv4B-3g25A:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		4 / 7 SER A 186
LEU A 271
ILE A 289
GLY A 303
 None
 0.90A 2v0mC-3g25A:
undetectable		 2v0mC-3g25A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		4 / 5 VAL A 425
VAL A 402
ASP A 401
SER A 395
 None
 1.32A 2x45A-3g25A:
undetectable		 2x45A-3g25A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		4 / 5 VAL A 425
VAL A 402
ASP A 401
SER A 395
 None
 1.30A 2x45C-3g25A:
undetectable		 2x45C-3g25A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 ASP A 125
THR A 207
GLU A 201
 None
 0.83A 2zifB-3g25A:
undetectable		 2zifB-3g25A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 TYR A 182
TYR A 223
ILE A 179
 None
 0.80A 3eteA-3g25A:
undetectable
3eteB-3g25A:
undetectable		 3eteA-3g25A:
23.17
3eteB-3g25A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 11 GLY A 240
GLY A  77
ALA A 242
THR A  79
ALA A 218
 None
 1.03A 3g88A-3g25A:
undetectable		 3g88A-3g25A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 11 GLY A 240
GLY A  77
ALA A 242
THR A  79
ALA A 218
 None
 1.04A 3g88B-3g25A:
undetectable		 3g88B-3g25A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 12 GLY A 240
GLY A  77
ALA A 242
THR A  79
ALA A 218
 None
 1.07A 3g89A-3g25A:
undetectable		 3g89A-3g25A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 11 GLY A 240
GLY A  77
ALA A 242
THR A  79
ALA A 218
 None
 1.07A 3g89B-3g25A:
undetectable		 3g89B-3g25A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 ASN A 184
ASP A 244
ARG A 105
 None
GOL  A 499 ( 2.8A)
None
 0.84A 3k13A-3g25A:
undetectable		 3k13A-3g25A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 12 ALA A 136
ILE A  96
PRO A  95
LEU A 144
THR A 188
 None
 1.16A 3nrrA-3g25A:
undetectable		 3nrrA-3g25A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 12 ALA A 136
ILE A  96
PRO A  95
LEU A 144
THR A 188
 None
 1.17A 3nrrB-3g25A:
undetectable		 3nrrB-3g25A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_1
(PROTEASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 9 ALA A 439
ILE A   8
GLY A  11
VAL A  29
ILE A  18
 None
None
PO4  A 502 (-3.5A)
None
None
 1.07A 3nuoA-3g25A:
undetectable		 3nuoA-3g25A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 10 ALA A 248
ASP A 408
SER A 304
ILE A 305
THR A 437
 None
 1.26A 3qgtA-3g25A:
undetectable		 3qgtA-3g25A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 ARG A 105
THR A  84
TRP A 102
 None
None
GOL  A 499 (-3.4A)
 1.17A 4d7hA-3g25A:
undetectable		 4d7hA-3g25A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		4 / 6 SER A 382
GLN A 386
VAL A 489
THR A 492
 None
 1.32A 4lnxA-3g25A:
undetectable		 4lnxA-3g25A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 12 ILE A 312
LEU A 315
VAL A 341
ALA A 378
SER A 382
 None
 1.38A 4m11C-3g25A:
undetectable		 4m11C-3g25A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 12 LEU A 315
VAL A 341
ALA A 378
SER A 382
LEU A 383
 None
 1.38A 4m11C-3g25A:
undetectable		 4m11C-3g25A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		4 / 5 TYR A 182
LEU A 445
ASP A 294
GLU A 221
 None
 1.14A 4nkvA-3g25A:
undetectable		 4nkvA-3g25A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		4 / 6 ASP A 244
GLU A 436
VAL A 412
ALA A 411
 GOL  A 499 ( 2.8A)
None
None
None
 0.95A 4nkvC-3g25A:
undetectable		 4nkvC-3g25A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		4 / 6 ARG A 151
ALA A 150
ASP A 145
LEU A 159
 None
 1.11A 4ot2A-3g25A:
undetectable		 4ot2A-3g25A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QI9_C_MTXC201_1
(DIHYDROFOLATE
REDUCTASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 11 ALA A 248
ASP A 408
SER A 304
ILE A 305
THR A 437
 None
 1.25A 4qi9C-3g25A:
undetectable		 4qi9C-3g25A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 12 ALA A 311
SER A 310
GLY A 267
GLN A 103
ALA A 359
 None
None
NA  A 500 (-3.8A)
None
None
 1.29A 4r29A-3g25A:
undetectable		 4r29A-3g25A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 GLU A 120
ARG A 124
GLN A 108
 None
 0.95A 4rtbA-3g25A:
undetectable		 4rtbA-3g25A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 GLU A 477
TYR A 385
GLU A 381
 None
None
PO4  A 504 (-2.7A)
 0.82A 4ryaA-3g25A:
undetectable		 4ryaA-3g25A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 ARG A 105
THR A  84
TRP A 102
 None
None
GOL  A 499 (-3.4A)
 1.13A 4ug5A-3g25A:
undetectable		 4ug5A-3g25A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 ARG A 105
THR A  84
TRP A 102
 None
None
GOL  A 499 (-3.4A)
 1.17A 4uglA-3g25A:
undetectable		 4uglA-3g25A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 12 LEU A 301
THR A 352
GLY A 284
GLY A 349
PHE A 135
 None
 1.03A 5d4uA-3g25A:
undetectable		 5d4uA-3g25A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 12 LEU A 301
THR A 352
GLY A 284
GLY A 349
PHE A 135
 None
 1.04A 5d4uB-3g25A:
undetectable		 5d4uB-3g25A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 12 GLY A 243
LEU A 249
GLY A 240
ILE A  78
GLY A 251
 None
 0.95A 5d4uC-3g25A:
undetectable		 5d4uC-3g25A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 12 GLY A 243
LEU A 249
GLY A 240
ILE A  78
GLY A 251
 None
 0.95A 5d4uD-3g25A:
undetectable		 5d4uD-3g25A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 ARG A 105
THR A  84
TRP A 102
 None
None
GOL  A 499 (-3.4A)
 1.15A 5g6cA-3g25A:
undetectable		 5g6cA-3g25A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		4 / 6 ILE A 424
ARG A 388
TYR A 482
TYR A 354
 None
 1.18A 5igyA-3g25A:
undetectable		 5igyA-3g25A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 12 THR A 287
THR A 288
ALA A 300
SER A 283
GLY A 284
 None
 1.21A 5lf7V-3g25A:
undetectable
5lf7b-3g25A:
undetectable		 5lf7V-3g25A:
20.86
5lf7b-3g25A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 12 THR A 287
THR A 288
ALA A 300
SER A 283
GLY A 284
 None
 1.20A 5lf7H-3g25A:
undetectable
5lf7N-3g25A:
undetectable		 5lf7H-3g25A:
20.86
5lf7N-3g25A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A220_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		5 / 9 LEU A 405
VAL A 407
LEU A 249
THR A 387
VAL A 390
 None
 1.33A 5mxbA-3g25A:
0.0		 5mxbA-3g25A:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		4 / 6 PHE A 191
ILE A 289
LEU A 129
GLY A 128
 None
 0.92A 5x5qE-3g25A:
undetectable		 5x5qE-3g25A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		4 / 5 HIS A 178
ASP A  89
TRP A 170
GLY A  93
 None
 1.32A 5x7pB-3g25A:
undetectable		 5x7pB-3g25A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		4 / 5 ASP A 408
ILE A  18
PHE A  20
ASN A 273
 None
 1.25A 6a93B-3g25A:
undetectable		 6a93B-3g25A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 LEU A 271
THR A  79
ASN A  80
 None
 0.74A 6baaE-3g25A:
undetectable		 6baaE-3g25A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 LEU A 271
THR A  79
ASN A  80
 None
 0.74A 6baaF-3g25A:
undetectable		 6baaF-3g25A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 LEU A 271
THR A  79
ASN A  80
 None
 0.74A 6baaG-3g25A:
undetectable		 6baaG-3g25A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 LEU A 271
THR A  79
ASN A  80
 None
 0.74A 6baaH-3g25A:
undetectable		 6baaH-3g25A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		3 / 3 GLU A 430
ASP A 470
PRO A 471
 None
 0.66A 6berA-3g25A:
undetectable		 6berA-3g25A:
3.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		4 / 5 ILE A 312
GLN A 327
THR A 379
LEU A 319
 None
 1.08A 6f3mD-3g25A:
undetectable		 6f3mD-3g25A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3g25 GLYCEROL KINASE
(Staphylococcus
aureus) 		4 / 7 ILE A 164
GLN A  10
GLU A  50
HIS A  46
 None
 1.11A 6j20A-3g25A:
undetectable		 6j20A-3g25A:
20.52