SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3g33 CCND3 PROTEIN
(Homo
sapiens) 		5 / 12 THR B 235
PHE B 163
LEU B  31
ASP B  24
HIS B 166
 None
 1.34A 2g72A-3g33B:
undetectable		 2g72A-3g33B:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_ACTA148_0
(UPF0066 PROTEIN
AF_0241)		 3g33 CCND3 PROTEIN
(Homo
sapiens) 		3 / 3 VAL B  39
GLU B  35
GLU B  36
 None
 0.81A 2nv4A-3g33B:
undetectable		 2nv4A-3g33B:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 3g33 CCND3 PROTEIN
(Homo
sapiens) 		3 / 3 GLU B 236
VAL B 237
CYH B 239
 None
 0.92A 3fbxA-3g33B:
undetectable		 3fbxA-3g33B:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3g33 CCND3 PROTEIN
(Homo
sapiens) 		3 / 3 CYH B 106
PRO B  79
ASP B  86
 None
 0.90A 3hlwB-3g33B:
undetectable		 3hlwB-3g33B:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3g33 CCND3 PROTEIN
(Homo
sapiens) 		5 / 12 ALA B 182
GLY B 206
LEU B 240
ALA B 211
GLU B 224
 None
 1.14A 4lg1B-3g33B:
undetectable		 4lg1B-3g33B:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 3g33 CCND3 PROTEIN
(Homo
sapiens) 		3 / 3 CYH B 106
PRO B  79
ASP B  86
 None
 0.85A 4pm5A-3g33B:
undetectable		 4pm5A-3g33B:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_2
(ESTROGEN RECEPTOR)		 3g33 CCND3 PROTEIN
(Homo
sapiens) 		4 / 5 LEU B 186
GLU B  76
LEU B 165
HIS B 181
 None
 1.12A 4xi3B-3g33B:
2.7		 4xi3B-3g33B:
23.44