SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g3b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 3g3b VARIABLE LYMPHOCYTE
RECEPTOR VLRB.2D
(Petromyzon
marinus) 		5 / 12 LEU A  82
LEU A  58
LEU A  34
LEU A  68
LEU A  65
 None
 1.07A 1sqnB-3g3bA:
undetectable		 1sqnB-3g3bA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3g3b VARIABLE LYMPHOCYTE
RECEPTOR VLRB.2D
(Petromyzon
marinus) 		3 / 3 HIS A 105
ASP A  59
ASN A  62
 None
 0.71A 1wg8B-3g3bA:
undetectable		 1wg8B-3g3bA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3g3b VARIABLE LYMPHOCYTE
RECEPTOR VLRB.2D
(Petromyzon
marinus) 		4 / 5 GLY A  17
PRO A  24
VAL A  23
ILE A  41
 None
 0.78A 2aoiA-3g3bA:
undetectable		 2aoiA-3g3bA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 3g3b VARIABLE LYMPHOCYTE
RECEPTOR VLRB.2D
(Petromyzon
marinus) 		4 / 7 ILE A 127
TYR A 122
PHE A  97
ASP A  98
 None
 1.13A 2qebA-3g3bA:
undetectable		 2qebA-3g3bA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 3g3b VARIABLE LYMPHOCYTE
RECEPTOR VLRB.2D
(Petromyzon
marinus) 		4 / 7 ILE A 127
TYR A 122
PHE A  97
ASP A  98
 None
 1.10A 2qebB-3g3bA:
undetectable		 2qebB-3g3bA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3g3b VARIABLE LYMPHOCYTE
RECEPTOR VLRB.2D
(Petromyzon
marinus) 		5 / 12 LEU A  82
LEU A 100
PRO A  28
THR A  12
THR A  56
 None
 1.18A 3dcjA-3g3bA:
undetectable
3dcjB-3g3bA:
undetectable		 3dcjA-3g3bA:
21.70
3dcjB-3g3bA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3g3b VARIABLE LYMPHOCYTE
RECEPTOR VLRB.2D
(Petromyzon
marinus) 		5 / 11 LEU A  84
ASN A  85
LEU A  58
LEU A  68
LEU A  44
 None
 1.37A 3ndvA-3g3bA:
undetectable
3ndvB-3g3bA:
undetectable		 3ndvA-3g3bA:
17.60
3ndvB-3g3bA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3g3b VARIABLE LYMPHOCYTE
RECEPTOR VLRB.2D
(Petromyzon
marinus) 		5 / 11 LEU A  68
LEU A  44
LEU A  84
ASN A  85
LEU A  58
 None
 1.36A 3ndvA-3g3bA:
undetectable
3ndvB-3g3bA:
undetectable		 3ndvA-3g3bA:
17.60
3ndvB-3g3bA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3g3b VARIABLE LYMPHOCYTE
RECEPTOR VLRB.2D
(Petromyzon
marinus) 		5 / 11 LEU A  84
ASN A  85
LEU A  58
LEU A  68
LEU A  44
 None
 1.36A 3ndvC-3g3bA:
undetectable
3ndvD-3g3bA:
undetectable		 3ndvC-3g3bA:
17.60
3ndvD-3g3bA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3g3b VARIABLE LYMPHOCYTE
RECEPTOR VLRB.2D
(Petromyzon
marinus) 		5 / 11 LEU A  68
LEU A  44
LEU A  84
ASN A  85
LEU A  58
 None
 1.38A 3ndvC-3g3bA:
undetectable
3ndvD-3g3bA:
undetectable		 3ndvC-3g3bA:
17.60
3ndvD-3g3bA:
17.60