SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g3o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 6 ARG A 440
ILE A 391
PHE A 353
GLU A 395
None
1.19A 1nsiA-3g3oA:
undetectable
1nsiB-3g3oA:
undetectable
1nsiA-3g3oA:
20.76
1nsiB-3g3oA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 6 PHE A 353
GLU A 395
ARG A 440
ILE A 391
None
1.19A 1nsiA-3g3oA:
undetectable
1nsiB-3g3oA:
undetectable
1nsiA-3g3oA:
20.76
1nsiB-3g3oA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 6 ARG A 440
ILE A 391
PHE A 353
GLU A 395
None
1.17A 1nsiC-3g3oA:
undetectable
1nsiD-3g3oA:
undetectable
1nsiC-3g3oA:
20.76
1nsiD-3g3oA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 6 PHE A 353
GLU A 395
ARG A 440
ILE A 391
None
1.13A 1nsiC-3g3oA:
undetectable
1nsiD-3g3oA:
undetectable
1nsiC-3g3oA:
20.76
1nsiD-3g3oA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 6 HIS A 446
PHE A 359
LEU A 343
ILE A 318
None
1.19A 1sbrA-3g3oA:
undetectable
1sbrB-3g3oA:
undetectable
1sbrA-3g3oA:
18.04
1sbrB-3g3oA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD207_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 8 LEU A 547
PHE A 469
PHE A 427
SER A 521
None
None
None
SO4  A1001 (-2.5A)
1.01A 1wrlC-3g3oA:
undetectable
1wrlD-3g3oA:
undetectable
1wrlC-3g3oA:
13.94
1wrlD-3g3oA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 7 ARG A 440
ILE A 391
PHE A 353
GLU A 395
None
1.19A 2nsiA-3g3oA:
undetectable
2nsiB-3g3oA:
undetectable
2nsiA-3g3oA:
20.76
2nsiB-3g3oA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 7 PHE A 353
GLU A 395
ARG A 440
ILE A 391
None
1.20A 2nsiA-3g3oA:
undetectable
2nsiB-3g3oA:
undetectable
2nsiA-3g3oA:
20.76
2nsiB-3g3oA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 7 ARG A 440
ILE A 391
PHE A 353
GLU A 395
None
1.17A 2nsiC-3g3oA:
undetectable
2nsiD-3g3oA:
undetectable
2nsiC-3g3oA:
20.76
2nsiD-3g3oA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 7 PHE A 353
GLU A 395
ARG A 440
ILE A 391
None
1.17A 2nsiC-3g3oA:
undetectable
2nsiD-3g3oA:
undetectable
2nsiC-3g3oA:
20.76
2nsiD-3g3oA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 8 ASP A 284
SER A 521
PHE A 523
ASP A 293
None
SO4  A1001 (-2.5A)
None
None
0.97A 2obvA-3g3oA:
undetectable
2obvA-3g3oA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 8 ASP A 284
SER A 521
PHE A 523
ASP A 293
None
SO4  A1001 (-2.5A)
None
None
0.90A 2p02A-3g3oA:
undetectable
2p02A-3g3oA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 7 ARG A 440
ILE A 391
PHE A 353
GLU A 395
None
1.18A 3e7gA-3g3oA:
undetectable
3e7gB-3g3oA:
undetectable
3e7gA-3g3oA:
20.70
3e7gB-3g3oA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 7 PHE A 353
GLU A 395
ARG A 440
ILE A 391
None
1.17A 3e7gA-3g3oA:
undetectable
3e7gB-3g3oA:
undetectable
3e7gA-3g3oA:
20.70
3e7gB-3g3oA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_C_H4BC2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 7 ARG A 440
ILE A 391
PHE A 353
GLU A 395
None
1.22A 3e7gC-3g3oA:
undetectable
3e7gD-3g3oA:
undetectable
3e7gC-3g3oA:
20.70
3e7gD-3g3oA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 8 PHE A 353
GLU A 395
ARG A 440
ILE A 391
None
1.21A 3e7gC-3g3oA:
undetectable
3e7gD-3g3oA:
undetectable
3e7gC-3g3oA:
20.70
3e7gD-3g3oA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
5 / 12 GLU A 354
GLY A 350
PHE A 359
ILE A 352
GLY A 355
None
1.33A 3ps9A-3g3oA:
undetectable
3ps9A-3g3oA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 5 ASP A 534
GLU A 465
GLY A 464
TYR A 531
None
1.35A 3w9tA-3g3oA:
undetectable
3w9tA-3g3oA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 5 ASP A 534
GLU A 465
GLY A 464
TYR A 531
None
1.36A 3w9tC-3g3oA:
undetectable
3w9tC-3g3oA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 5 ASP A 534
GLU A 465
GLY A 464
TYR A 531
None
1.35A 3w9tD-3g3oA:
undetectable
3w9tD-3g3oA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 5 ASP A 534
GLU A 465
GLY A 464
TYR A 531
None
1.35A 3w9tG-3g3oA:
undetectable
3w9tG-3g3oA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 8 ARG A 440
ILE A 391
PHE A 353
GLU A 395
None
1.22A 4cx7A-3g3oA:
undetectable
4cx7B-3g3oA:
undetectable
4cx7A-3g3oA:
20.76
4cx7B-3g3oA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 8 PHE A 353
GLU A 395
ARG A 440
ILE A 391
None
1.19A 4cx7A-3g3oA:
undetectable
4cx7B-3g3oA:
undetectable
4cx7A-3g3oA:
20.76
4cx7B-3g3oA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 8 ARG A 440
ILE A 391
PHE A 353
GLU A 395
None
1.14A 4cx7C-3g3oA:
undetectable
4cx7D-3g3oA:
undetectable
4cx7C-3g3oA:
20.76
4cx7D-3g3oA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_D_H4BD600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 7 PHE A 353
GLU A 395
ARG A 440
ILE A 391
None
1.15A 4cx7C-3g3oA:
undetectable
4cx7D-3g3oA:
undetectable
4cx7C-3g3oA:
20.76
4cx7D-3g3oA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
3 / 3 LYS A 275
THR A 405
ILE A 421
None
0.81A 4e0fB-3g3oA:
undetectable
4e0fB-3g3oA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 7 LEU A 530
TYR A 531
ILE A 439
GLY A 464
None
0.93A 4eq4A-3g3oA:
undetectable
4eq4A-3g3oA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 7 LEU A 530
TYR A 531
ILE A 439
GLY A 464
None
0.95A 4eqlA-3g3oA:
undetectable
4eqlA-3g3oA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
3 / 3 ARG A 401
ASP A 431
ASP A 534
None
0.84A 4kicB-3g3oA:
undetectable
4kicB-3g3oA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 8 ASP A 284
SER A 521
PHE A 523
ASP A 293
None
SO4  A1001 (-2.5A)
None
None
0.95A 4kttA-3g3oA:
undetectable
4kttA-3g3oA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 8 ASP A 284
SER A 521
PHE A 523
ASP A 293
None
SO4  A1001 (-2.5A)
None
None
0.89A 4kttC-3g3oA:
undetectable
4kttC-3g3oA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 6 LEU A 530
TYR A 531
ILE A 439
GLY A 464
None
1.00A 4l39A-3g3oA:
undetectable
4l39A-3g3oA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
3 / 3 ASP A 441
VAL A 399
ASN A 349
None
0.80A 4lmnA-3g3oA:
1.9
4lmnA-3g3oA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 8 ASP A 284
SER A 521
PHE A 523
ASP A 293
None
SO4  A1001 (-2.5A)
None
None
0.86A 4ndnA-3g3oA:
undetectable
4ndnA-3g3oA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 7 ASP A 284
SER A 521
PHE A 523
ASP A 293
None
SO4  A1001 (-2.5A)
None
None
0.92A 4ndnC-3g3oA:
undetectable
4ndnC-3g3oA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_B_H4BB1011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 7 PHE A 353
GLU A 395
ARG A 440
ILE A 391
None
1.21A 4nosA-3g3oA:
undetectable
4nosB-3g3oA:
undetectable
4nosA-3g3oA:
20.65
4nosB-3g3oA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_C_H4BC2011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 7 ARG A 440
ILE A 391
PHE A 353
GLU A 395
None
1.25A 4nosC-3g3oA:
undetectable
4nosD-3g3oA:
undetectable
4nosC-3g3oA:
20.65
4nosD-3g3oA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_D_H4BD3011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 6 PHE A 353
GLU A 395
ARG A 440
ILE A 391
None
1.19A 4nosC-3g3oA:
undetectable
4nosD-3g3oA:
undetectable
4nosC-3g3oA:
20.65
4nosD-3g3oA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 7 ASP A 284
SER A 521
PHE A 523
ASP A 293
None
SO4  A1001 (-2.5A)
None
None
1.02A 4odjA-3g3oA:
undetectable
4odjA-3g3oA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 8 ASP A 284
SER A 521
PHE A 523
ASP A 293
None
SO4  A1001 (-2.5A)
None
None
0.93A 5a1iA-3g3oA:
undetectable
5a1iA-3g3oA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 7 ASP A 284
SER A 521
PHE A 523
ASP A 293
None
SO4  A1001 (-2.5A)
None
None
0.93A 5a1iA-3g3oA:
undetectable
5a1iA-3g3oA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 7 LYS A 365
GLN A 362
PHE A 384
LEU A 380
None
0.95A 5b3sP-3g3oA:
undetectable
5b3sP-3g3oA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 8 ASP A 284
SER A 521
PHE A 523
ASP A 293
None
SO4  A1001 (-2.5A)
None
None
0.95A 6fbnB-3g3oA:
undetectable
6fbnB-3g3oA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 8 ASP A 284
SER A 521
PHE A 523
ASP A 293
None
SO4  A1001 (-2.5A)
None
None
0.93A 6fboA-3g3oA:
undetectable
6fboA-3g3oA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 8 ASP A 284
SER A 521
PHE A 523
ASP A 293
None
SO4  A1001 (-2.5A)
None
None
0.93A 6fcbA-3g3oA:
undetectable
6fcbA-3g3oA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 8 ASP A 284
SER A 521
PHE A 523
ASP A 293
None
SO4  A1001 (-2.5A)
None
None
0.92A 6fcdA-3g3oA:
undetectable
6fcdA-3g3oA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3g3o VACUOLAR TRANSPORTER
CHAPERONE 2

(Saccharomyces
cerevisiae)
4 / 7 ASP A 284
SER A 521
PHE A 523
ASP A 293
None
SO4  A1001 (-2.5A)
None
None
0.94A 6g6rA-3g3oA:
undetectable
6g6rA-3g3oA:
22.00