SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g3s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_A_CHCA202_1
(BILE ACID RECEPTOR)		 3g3s GCN5-RELATED
N-ACETYLTRANSFERASE
(Streptococcus
suis) 		5 / 12 MET A 125
ALA A 204
PHE A 107
ILE A 184
TYR A 217
 None
 1.44A 1osvA-3g3sA:
0.0		 1osvA-3g3sA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_B_CHDB500_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3g3s GCN5-RELATED
N-ACETYLTRANSFERASE
(Streptococcus
suis) 		4 / 4 LEU A  74
VAL A  75
ILE A  73
TRP A 247
 None
 1.32A 1s9qB-3g3sA:
undetectable		 1s9qB-3g3sA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3g3s GCN5-RELATED
N-ACETYLTRANSFERASE
(Streptococcus
suis) 		3 / 3 LEU A 197
LEU A 199
ARG A 191
 None
 0.72A 3hcnB-3g3sA:
undetectable		 3hcnB-3g3sA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEC_A_STIA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3g3s GCN5-RELATED
N-ACETYLTRANSFERASE
(Streptococcus
suis) 		4 / 4 LEU A  24
MET A   1
ILE A  66
ASP A  34
 EDO  A 251 (-3.9A)
None
None
None
 1.43A 3hecA-3g3sA:
undetectable		 3hecA-3g3sA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 3g3s GCN5-RELATED
N-ACETYLTRANSFERASE
(Streptococcus
suis) 		3 / 3 HIS A 223
ARG A  98
GLU A 246
 None
EDO  A 252 (-3.7A)
None
 1.01A 3qf1A-3g3sA:
undetectable		 3qf1A-3g3sA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 3g3s GCN5-RELATED
N-ACETYLTRANSFERASE
(Streptococcus
suis) 		5 / 12 THR A 135
ASN A 131
ALA A 174
GLY A 173
GLN A 206
 None
 1.02A 3v3oA-3g3sA:
undetectable		 3v3oA-3g3sA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZE_A_BAXA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 3g3s GCN5-RELATED
N-ACETYLTRANSFERASE
(Streptococcus
suis) 		5 / 8 VAL A 171
VAL A 170
CYH A 136
ILE A 164
ASP A 124
 None
 1.26A 3wzeA-3g3sA:
undetectable		 3wzeA-3g3sA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 3g3s GCN5-RELATED
N-ACETYLTRANSFERASE
(Streptococcus
suis) 		4 / 4 LEU A 137
ILE A 128
GLY A 147
PHE A 155
 None
 0.97A 4dc3A-3g3sA:
undetectable		 4dc3A-3g3sA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3g3s GCN5-RELATED
N-ACETYLTRANSFERASE
(Streptococcus
suis) 		4 / 5 LEU A  64
VAL A  88
GLU A  87
LEU A  84
 None
 1.05A 5xooB-3g3sA:
undetectable		 5xooB-3g3sA:
14.86