SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g3t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA426_0
(FERROCHELATASE)		 3g3t VACUOLAR TRANSPORTER
CHAPERONE 4
(Saccharomyces
cerevisiae) 		4 / 4 LEU A 219
PRO A 220
LEU A 366
ARG A 371
 None
 1.46A 2qd2A-3g3tA:
undetectable		 2qd2A-3g3tA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3g3t VACUOLAR TRANSPORTER
CHAPERONE 4
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 469
ASP A 416
ASP A 413
GLU A 245
 None
None
None
PO4  A1003 (-3.6A)
 1.01A 4feuD-3g3tA:
undetectable		 4feuD-3g3tA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 3g3t VACUOLAR TRANSPORTER
CHAPERONE 4
(Saccharomyces
cerevisiae) 		3 / 3 PHE A 409
VAL A 383
GLU A 385
 None
 0.71A 4fvqA-3g3tA:
undetectable		 4fvqA-3g3tA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 3g3t VACUOLAR TRANSPORTER
CHAPERONE 4
(Saccharomyces
cerevisiae) 		4 / 6 LYS A 458
GLY A 462
TYR A 250
ALA A 464
 None
 1.31A 4yshB-3g3tA:
undetectable		 4yshB-3g3tA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 3g3t VACUOLAR TRANSPORTER
CHAPERONE 4
(Saccharomyces
cerevisiae) 		4 / 6 VAL A 445
VAL A 450
TYR A 201
ILE A 374
 None
 0.94A 5pbeA-3g3tA:
undetectable		 5pbeA-3g3tA:
20.98