SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g4f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		3 / 3 ALA A 442
VAL A 491
TRP A 495
 None
 0.92A 1bdwA-3g4fA:
undetectable
1bdwB-3g4fA:
undetectable		 1bdwA-3g4fA:
2.51
1bdwB-3g4fA:
2.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		4 / 7 ARG A 367
GLU A 369
ALA A 433
ALA A 434
 None
 1.07A 2ejfA-3g4fA:
undetectable		 2ejfA-3g4fA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		4 / 7 MET A 412
ILE A 300
GLY A 292
MET A 421
 None
 1.11A 2pnjB-3g4fA:
undetectable		 2pnjB-3g4fA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		3 / 3 LEU A 503
ASN A 499
ARG A 122
 None
 0.60A 2qhfA-3g4fA:
undetectable		 2qhfA-3g4fA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		5 / 9 SER A 161
LEU A 201
ILE A 175
GLU A 123
GLY A 208
 None
 1.18A 2v0mB-3g4fA:
undetectable		 2v0mB-3g4fA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		4 / 7 TYR A 472
CYH A 471
GLU A 475
TYR A 476
 None
 1.30A 2xytG-3g4fA:
undetectable		 2xytG-3g4fA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		3 / 3 LEU A 171
TRP A 495
TYR A 158
 None
 1.00A 3aicF-3g4fA:
3.3		 3aicF-3g4fA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_1
(PHOSPHOLIPASE A2)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		5 / 10 VAL A 273
VAL A 274
GLU A 275
GLY A 276
LYS A 541
 None
 1.47A 3bjwD-3g4fA:
undetectable		 3bjwD-3g4fA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		4 / 8 VAL A  85
HIS A  88
ASP A 238
ILE A 237
 None
 0.78A 3fi0I-3g4fA:
undetectable		 3fi0I-3g4fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		4 / 7 VAL A  85
HIS A  88
ASP A 238
ILE A 237
 None
 0.81A 3fi0P-3g4fA:
undetectable		 3fi0P-3g4fA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		3 / 4 SER A 546
GLY A 208
GLU A 123
 None
 0.68A 3raeA-3g4fA:
undetectable
3raeC-3g4fA:
undetectable		 3raeA-3g4fA:
24.07
3raeC-3g4fA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		4 / 6 SER A 417
LEU A 413
MET A 412
THR A 416
 None
 1.36A 3thrB-3g4fA:
undetectable		 3thrB-3g4fA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		3 / 3 TYR A 313
GLU A 317
TYR A 316
 None
 0.95A 3ug8A-3g4fA:
undetectable		 3ug8A-3g4fA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		3 / 3 GLU A 336
ASP A 335
ASP A 330
 None
 0.73A 4gc9A-3g4fA:
undetectable		 4gc9A-3g4fA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J03_A_FVSA603_1
(BIFUNCTIONAL EPOXIDE
HYDROLASE 2)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		5 / 12 TYR A 340
ILE A 337
LEU A 413
TYR A 382
LEU A 348
 None
None
None
MG  A 605 ( 4.8A)
None
 1.33A 4j03A-3g4fA:
undetectable		 4j03A-3g4fA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		3 / 4 SER A 546
GLY A 208
GLU A 123
 None
 0.58A 4juoA-3g4fA:
undetectable
4juoC-3g4fA:
undetectable		 4juoA-3g4fA:
24.07
4juoC-3g4fA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA505_0
(RNA POLYMERASE
3D-POL)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		3 / 3 CYH A 254
ASN A  38
LYS A 258
 None
 1.20A 4k50A-3g4fA:
1.3		 4k50A-3g4fA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		3 / 3 LEU A 547
ARG A 293
MET A 421
 None
 1.00A 4m11C-3g4fA:
undetectable		 4m11C-3g4fA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		4 / 7 ASN A 373
LEU A 348
MET A 295
ILE A 326
 None
 0.97A 4okwA-3g4fA:
undetectable		 4okwA-3g4fA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		4 / 6 THR A 426
GLU A 428
THR A 429
THR A 506
 None
 0.86A 4pgfA-3g4fA:
undetectable		 4pgfA-3g4fA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		4 / 8 ASP A 311
ASP A 307
ASP A 308
ILE A 300
 MG  A 605 ( 2.9A)
MG  A 604 (-2.2A)
None
None
 1.01A 5cfsA-3g4fA:
2.2		 5cfsA-3g4fA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_A_BBIA403_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		4 / 6 ARG A 528
GLU A 529
GLU A 492
VAL A 491
 None
 1.35A 5h4dA-3g4fA:
undetectable		 5h4dA-3g4fA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1
(Gossypium
arboreum) 		4 / 6 TYR A 217
LEU A 193
GLU A 156
LEU A 155
 None
 0.83A 5xooA-3g4fA:
undetectable		 5xooA-3g4fA:
10.93