SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g5a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		5 / 9 LEU A  13
LEU A  73
GLU A  80
LYS A  39
ILE A  35
 None
 1.50A 1gx8A-3g5aA:
undetectable		 1gx8A-3g5aA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		4 / 7 VAL A  69
LEU A  73
THR A  14
LEU A  13
 None
 0.94A 1jgsA-3g5aA:
undetectable		 1jgsA-3g5aA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		4 / 8 ILE A 277
LYS A  65
PHE A 114
GLY A 224
 None
APC  A 305 (-2.9A)
None
None
 1.02A 1os6A-3g5aA:
undetectable		 1os6A-3g5aA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_B_H4BB1001_1
(HYPOTHETICAL PROTEIN
PH0634)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		5 / 10 ILE A 121
PHE A 107
GLU A 141
THR A 113
GLU A 118
 None
APC  A 305 (-4.9A)
None
None
None
 1.31A 2dttA-3g5aA:
0.0
2dttB-3g5aA:
0.0		 2dttA-3g5aA:
17.39
2dttB-3g5aA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		5 / 12 LEU A 205
GLY A 287
ASN A 232
LEU A 223
PHE A 114
 None
None
None
APC  A 305 (-4.4A)
None
 1.16A 2zzmA-3g5aA:
undetectable		 2zzmA-3g5aA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		4 / 7 LEU A 132
GLU A 134
ASP A 109
SER A 125
 None
 1.28A 3dzgA-3g5aA:
undetectable		 3dzgA-3g5aA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		4 / 7 LEU A 132
GLU A 134
ASP A 109
SER A 125
 None
 1.25A 3dzgB-3g5aA:
undetectable		 3dzgB-3g5aA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		4 / 7 LEU A 132
GLU A 134
ASP A 109
THR A 124
 None
 1.17A 3dzgB-3g5aA:
undetectable		 3dzgB-3g5aA:
19.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G59_A_ACTA306_0
(FMN
ADENYLYLTRANSFERASE)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		4 / 5 SER A  60
PHE A 147
ILE A 162
TRP A 184
 APC  A 305 ( 2.5A)
FMN  A 306 (-3.8A)
FMN  A 306 ( 4.3A)
FMN  A 306 (-3.5A)
 0.46A 3g59A-3g5aA:
46.3		 3g59A-3g5aA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		4 / 8 SER A 203
PHE A 204
TYR A  17
LEU A  70
 None
 1.08A 3jq7C-3g5aA:
undetectable		 3jq7C-3g5aA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		3 / 3 GLU A 210
LEU A   9
LEU A  78
 None
 0.75A 3ohtA-3g5aA:
undetectable		 3ohtA-3g5aA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		3 / 3 GLU A 210
LEU A   9
LEU A  78
 None
 0.75A 3ohtB-3g5aA:
undetectable		 3ohtB-3g5aA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		3 / 3 TYR A 188
ASP A 186
ASP A 181
 None
None
FMN  A 306 (-3.5A)
 0.77A 3ou7B-3g5aA:
1.8		 3ou7B-3g5aA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		4 / 7 ILE A 277
LYS A  65
PHE A 114
GLY A 224
 None
APC  A 305 (-2.9A)
None
None
 0.99A 3sj0X-3g5aA:
undetectable		 3sj0X-3g5aA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		4 / 5 THR A 221
GLY A 299
PRO A 231
ASN A 232
 None
 1.17A 3u8qA-3g5aA:
undetectable		 3u8qA-3g5aA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		4 / 5 LEU A   9
TYR A  11
LEU A  13
TYR A 256
 None
 1.22A 5ki6A-3g5aA:
undetectable		 5ki6A-3g5aA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		3 / 3 TYR A 216
SER A 222
TRP A 202
 APC  A 305 (-4.7A)
APC  A 305 (-2.5A)
None
 0.98A 5n8jB-3g5aA:
undetectable		 5n8jB-3g5aA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		3 / 3 TYR A 216
SER A 222
TRP A 202
 APC  A 305 (-4.7A)
APC  A 305 (-2.5A)
None
 0.99A 5n8jA-3g5aA:
undetectable		 5n8jA-3g5aA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		5 / 12 LEU A  78
LEU A 103
LEU A 130
LEU A  71
LEU A  73
 None
 0.89A 5nfjA-3g5aA:
undetectable		 5nfjA-3g5aA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7J_A_TESA502_0
(CYTOCHROME P450)		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		4 / 7 LEU A 103
LEU A   3
ALA A   6
ALA A   7
 None
 0.79A 6a7jA-3g5aA:
undetectable		 6a7jA-3g5aA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 3g5a FMN
ADENYLYLTRANSFERASE
([Candida]
glabrata) 		4 / 8 LEU A 130
LEU A 132
LEU A  70
GLY A 163
 None
None
None
APC  A 305 (-3.2A)
 0.90A 6ce2A-3g5aA:
undetectable		 6ce2A-3g5aA:
16.99