SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g5k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3g5k PEPTIDE DEFORMYLASE,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 GLY A 113
ILE A 167
HIS A 160
HIS A 156
VAL A 117
 BB2  A1001 (-3.7A)
None
CO  A1002 ( 3.3A)
CO  A1002 ( 3.2A)
None
 1.25A 1tmxB-3g5kA:
undetectable		 1tmxB-3g5kA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 3g5k PEPTIDE DEFORMYLASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 4 VAL A  24
ASP A 136
LEU A  92
ARG A  62
 None
 1.29A 2ziaA-3g5kA:
undetectable		 2ziaA-3g5kA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 3g5k PEPTIDE DEFORMYLASE,
MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 HIS A 156
GLU A 157
HIS A 160
 CO  A1002 ( 3.2A)
BB2  A1001 (-2.6A)
CO  A1002 ( 3.3A)
 0.19A 3kecB-3g5kA:
undetectable		 3kecB-3g5kA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3g5k PEPTIDE DEFORMYLASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 7 VAL A 102
ILE A 154
CYH A 164
PHE A 127
 None
 0.90A 5hieC-3g5kA:
undetectable		 5hieC-3g5kA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 3g5k PEPTIDE DEFORMYLASE,
MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 ARG A 152
HIS A 156
ARG A 126
 None
CO  A1002 ( 3.2A)
None
 1.17A 5iaoF-3g5kA:
undetectable		 5iaoF-3g5kA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3g5k PEPTIDE DEFORMYLASE,
MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 GLU A 157
HIS A 156
ARG A 152
 BB2  A1001 (-2.6A)
CO  A1002 ( 3.2A)
None
 0.94A 5uunA-3g5kA:
undetectable		 5uunA-3g5kA:
20.26