SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g5l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_0
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		5 / 12 GLY A  50
GLY A  52
LEU A  73
GLU A  98
ALA A 115
 None
 0.73A 2fk8A-3g5lA:
16.1		 2fk8A-3g5lA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		4 / 7 SER A 138
VAL A 109
LYS A  44
SER A 136
 None
 1.14A 2j9cA-3g5lA:
undetectable
2j9cB-3g5lA:
undetectable
2j9cC-3g5lA:
undetectable		 2j9cA-3g5lA:
20.08
2j9cB-3g5lA:
20.08
2j9cC-3g5lA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		5 / 12 GLY A  50
GLY A  52
GLY A  54
LEU A  73
ILE A  97
 None
 0.67A 2oxtB-3g5lA:
9.3		 2oxtB-3g5lA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_0
(N,N-DIMETHYLTRANSFER
ASE)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		6 / 12 GLY A  52
HIS A  56
LEU A  73
SER A  74
MET A  77
TYR A 118
 None
 0.73A 3bxoA-3g5lA:
16.4		 3bxoA-3g5lA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_0
(N,N-DIMETHYLTRANSFER
ASE)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		6 / 12 GLY A  52
HIS A  56
LEU A  73
SER A  74
MET A  77
TYR A 118
 None
 0.73A 3bxoB-3g5lA:
15.4		 3bxoB-3g5lA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		3 / 3 PHE A 122
CYH A 126
PHE A 139
 None
 0.93A 3cr5X-3g5lA:
undetectable		 3cr5X-3g5lA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_0
(N-METHYLTRANSFERASE)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		5 / 12 GLY A  52
HIS A  56
LEU A  73
SER A  74
MET A  77
 None
 0.69A 3pfgA-3g5lA:
15.3		 3pfgA-3g5lA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		4 / 5 ILE A  58
THR A  85
THR A  86
SER A  87
 None
 0.90A 3snfA-3g5lA:
undetectable		 3snfA-3g5lA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		5 / 12 GLY A  50
GLY A  52
ASP A  72
MET A  77
ALA A 115
 None
 0.28A 4iv8A-3g5lA:
18.6		 4iv8A-3g5lA:
26.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		6 / 12 GLY A  50
GLY A  52
ASP A  72
MET A  77
ILE A  97
LEU A 116
 None
 1.42A 4iv8A-3g5lA:
18.6		 4iv8A-3g5lA:
26.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		5 / 12 GLY A  50
GLY A  52
ASP A  72
MET A  77
ALA A 115
 None
 0.31A 4iv8B-3g5lA:
18.6		 4iv8B-3g5lA:
26.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		6 / 12 GLY A  50
GLY A  52
ASP A  72
MET A  77
ILE A  97
LEU A 116
 None
 1.42A 4iv8B-3g5lA:
18.6		 4iv8B-3g5lA:
26.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		4 / 5 LYS A  36
LEU A  34
GLU A  33
LEU A 237
 None
 1.24A 4k4yA-3g5lA:
undetectable		 4k4yA-3g5lA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		4 / 4 LYS A  36
LEU A  34
GLU A  33
LEU A 237
 None
 1.27A 4k4yE-3g5lA:
undetectable		 4k4yE-3g5lA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		4 / 5 LYS A  36
LEU A  34
GLU A  33
LEU A 237
 None
 1.24A 4k4yI-3g5lA:
undetectable		 4k4yI-3g5lA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		5 / 12 GLY A  50
GLY A  52
SER A  74
MET A  77
ALA A 115
 None
 0.70A 4qtuB-3g5lA:
16.7		 4qtuB-3g5lA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		6 / 12 GLY A  50
GLY A  52
SER A  74
MET A  77
SER A 113
ALA A 115
 None
 1.48A 4qtuD-3g5lA:
17.4		 4qtuD-3g5lA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		5 / 12 GLY A  50
ASP A  72
LEU A  73
SER A  74
ILE A  97
 None
 0.51A 5dpdB-3g5lA:
15.1		 5dpdB-3g5lA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		3 / 3 GLU A 175
HIS A 191
ARG A 171
 None
 0.96A 5uunA-3g5lA:
undetectable		 5uunA-3g5lA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		4 / 7 ALA A 150
THR A 149
VAL A 169
TRP A 167
 None
 0.84A 6cduA-3g5lA:
undetectable
6cduE-3g5lA:
undetectable		 6cduA-3g5lA:
18.98
6cduE-3g5lA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_B_EY4B500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		4 / 6 VAL A 169
TRP A 167
ALA A 150
THR A 149
 None
 0.95A 6cduB-3g5lA:
undetectable
6cduC-3g5lA:
undetectable		 6cduB-3g5lA:
18.98
6cduC-3g5lA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		4 / 8 VAL A 169
TRP A 167
ALA A 150
THR A 149
 None
 0.88A 6cduD-3g5lA:
undetectable
6cduE-3g5lA:
undetectable		 6cduD-3g5lA:
18.98
6cduE-3g5lA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		4 / 7 ALA A 150
THR A 149
VAL A 169
TRP A 167
 None
 0.86A 6cduF-3g5lA:
undetectable
6cduJ-3g5lA:
undetectable		 6cduF-3g5lA:
18.98
6cduJ-3g5lA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		4 / 7 VAL A 169
TRP A 167
ALA A 150
THR A 149
 None
 0.92A 6cduH-3g5lA:
undetectable
6cduI-3g5lA:
undetectable		 6cduH-3g5lA:
18.98
6cduI-3g5lA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 3g5l PUTATIVE
S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE
(Listeria
monocytogenes) 		4 / 8 LEU A  34
VAL A  46
ASP A  48
VAL A 109
 None
 1.09A 6cp4A-3g5lA:
undetectable		 6cp4A-3g5lA:
20.05