SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g5o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3g5o UNCHARACTERIZED
PROTEIN RV2866
(Mycobacterium
tuberculosis) 		4 / 7 LEU B  77
VAL B  56
GLY B  57
TYR B  75
 None
 1.01A 1lweA-3g5oB:
undetectable		 1lweA-3g5oB:
9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVU_A_PRLA196_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 3g5o UNCHARACTERIZED
PROTEIN RV2866
(Mycobacterium
tuberculosis) 		4 / 6 LEU B  49
THR B  74
TYR B  75
TYR B  79
 None
 1.50A 1qvuA-3g5oB:
undetectable		 1qvuA-3g5oB:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3g5o UNCHARACTERIZED
PROTEIN RV2865
UNCHARACTERIZED
PROTEIN RV2866
(Mycobacterium
tuberculosis) 		5 / 10 LEU B  77
ALA B  45
ILE A  89
ASP B  29
LEU B  30
 None
 0.95A 1yi4A-3g5oB:
undetectable		 1yi4A-3g5oB:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 3g5o UNCHARACTERIZED
PROTEIN RV2865
UNCHARACTERIZED
PROTEIN RV2866
(Mycobacterium
tuberculosis) 		5 / 12 ILE A  71
SER A  70
ILE A  67
LEU B  78
ILE B  90
 None
 1.04A 2nnhA-3g5oA:
undetectable		 2nnhA-3g5oA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 3g5o UNCHARACTERIZED
PROTEIN RV2866
(Mycobacterium
tuberculosis) 		4 / 7 ILE B  37
ALA B  40
GLY B  73
THR B  74
 None
 0.77A 2xrzB-3g5oB:
undetectable		 2xrzB-3g5oB:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3g5o UNCHARACTERIZED
PROTEIN RV2866
(Mycobacterium
tuberculosis) 		5 / 12 LEU B  30
LEU B  38
PRO B  53
THR B  19
VAL B  41
 None
 1.23A 3dcjA-3g5oB:
undetectable
3dcjB-3g5oB:
undetectable		 3dcjA-3g5oB:
18.31
3dcjB-3g5oB:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3g5o UNCHARACTERIZED
PROTEIN RV2865
UNCHARACTERIZED
PROTEIN RV2866
(Mycobacterium
tuberculosis;
Mycobacterium
tuberculosis) 		5 / 12 ILE A  89
LEU B  38
PRO B  53
THR B  19
VAL B  41
 None
 1.25A 3dcjA-3g5oA:
undetectable
3dcjB-3g5oA:
undetectable		 3dcjA-3g5oA:
20.97
3dcjB-3g5oA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 3g5o UNCHARACTERIZED
PROTEIN RV2865
UNCHARACTERIZED
PROTEIN RV2866
(Mycobacterium
tuberculosis) 		5 / 12 PHE B  22
PHE B  46
THR B  19
ALA A  91
GLU A  88
 None
 1.28A 5vcgA-3g5oB:
undetectable		 5vcgA-3g5oB:
15.02