SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g65'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3g65 CHECKPOINT PROTEIN
HUS1
(Homo
sapiens) 		4 / 7 MET C  69
GLN C  60
PHE C   3
ASN C  40
 None
 1.12A 1t9wA-3g65C:
undetectable		 1t9wA-3g65C:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)		 3g65 CHECKPOINT PROTEIN
HUS1
(Homo
sapiens) 		5 / 12 LEU C 192
VAL C 201
GLU C 195
THR C 196
ILE C 234
 None
 1.03A 2vn0A-3g65C:
undetectable		 2vn0A-3g65C:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 3g65 CHECKPOINT PROTEIN
HUS1
(Homo
sapiens) 		4 / 5 VAL C 151
VAL C 150
PHE C 263
ARG C  33
 None
 1.37A 3bjwH-3g65C:
undetectable		 3bjwH-3g65C:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3g65 CHECKPOINT PROTEIN
HUS1
(Homo
sapiens) 		5 / 12 LEU C  92
PHE C  16
LEU C 101
ILE C  23
SER C 116
 None
 1.31A 3w1wA-3g65C:
undetectable		 3w1wA-3g65C:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3g65 CHECKPOINT PROTEIN
HUS1
(Homo
sapiens) 		4 / 6 ASN C 191
GLU C 195
GLU C 183
GLU C 229
 None
 1.10A 4mi4A-3g65C:
undetectable		 4mi4A-3g65C:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3g65 CHECKPOINT PROTEIN
HUS1
(Homo
sapiens) 		4 / 7 ASN C 191
GLU C 195
GLU C 183
GLU C 229
 None
 1.11A 4mi4B-3g65C:
undetectable
4mi4C-3g65C:
undetectable		 4mi4B-3g65C:
21.15
4mi4C-3g65C:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3g65 CHECKPOINT PROTEIN
HUS1
(Homo
sapiens) 		4 / 7 ASN C 191
GLU C 195
GLU C 183
GLU C 229
 None
 1.10A 4mi4A-3g65C:
undetectable
4mi4C-3g65C:
undetectable		 4mi4A-3g65C:
21.15
4mi4C-3g65C:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3g65 CHECKPOINT PROTEIN
HUS1
(Homo
sapiens) 		4 / 8 ASN C 191
GLU C 195
GLU C 183
GLU C 229
 None
 1.10A 4mj8A-3g65C:
undetectable
4mj8C-3g65C:
undetectable		 4mj8A-3g65C:
21.71
4mj8C-3g65C:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3g65 CHECKPOINT PROTEIN
HUS1
(Homo
sapiens) 		4 / 8 ASN C 191
GLU C 195
GLU C 183
GLU C 229
 None
 1.11A 4mj8B-3g65C:
undetectable
4mj8C-3g65C:
undetectable		 4mj8B-3g65C:
21.71
4mj8C-3g65C:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3g65 CHECKPOINT PROTEIN
HUS1
(Homo
sapiens) 		4 / 7 ASN C 191
GLU C 195
GLU C 183
GLU C 229
 None
 1.09A 4mj8C-3g65C:
undetectable		 4mj8C-3g65C:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3g65 CHECKPOINT PROTEIN
HUS1
(Homo
sapiens) 		4 / 7 ASN C 191
GLU C 195
GLU C 183
GLU C 229
 None
 1.20A 4r87I-3g65C:
undetectable		 4r87I-3g65C:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 3g65 CHECKPOINT PROTEIN
HUS1
(Homo
sapiens) 		4 / 5 VAL C 169
THR C 165
LEU C 180
VAL C 261
 None
 1.02A 6bqgA-3g65C:
undetectable		 6bqgA-3g65C:
13.57