SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g6i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X2N_A_X2NA1480_1 (LANOSTEROL 14-ALPHA-DEMETHYLASE)	3g6i	PUTATIVE OUTER MEMBRANE PROTEIN, PART OF CARBOHYDRATE BINDING COMPLEX (Bacteroides thetaiotaomicron)	5 / 12	TYR A 66 PRO A 116 ALA A 117 ALA A 176 ALA A 173	None	1.15A	2x2nA-3g6iA: undetectable	2x2nA-3g6iA: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X2N_B_X2NB1479_1 (LANOSTEROL 14-ALPHA-DEMETHYLASE)	3g6i	PUTATIVE OUTER MEMBRANE PROTEIN, PART OF CARBOHYDRATE BINDING COMPLEX (Bacteroides thetaiotaomicron)	6 / 12	PHE A 115 TYR A 66 PRO A 116 ALA A 117 ALA A 176 ALA A 173	None	1.39A	2x2nB-3g6iA: undetectable	2x2nB-3g6iA: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X2N_C_X2NC1479_1 (LANOSTEROL 14-ALPHA-DEMETHYLASE)	3g6i	PUTATIVE OUTER MEMBRANE PROTEIN, PART OF CARBOHYDRATE BINDING COMPLEX (Bacteroides thetaiotaomicron)	5 / 12	PHE A 115 TYR A 66 PRO A 116 ALA A 176 ALA A 173	None	1.27A	2x2nC-3g6iA: undetectable	2x2nC-3g6iA: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DH0_B_SAMB300_1 (SAM DEPENDENT METHYLTRANSFERASE)	3g6i	PUTATIVE OUTER MEMBRANE PROTEIN, PART OF CARBOHYDRATE BINDING COMPLEX (Bacteroides thetaiotaomicron)	4 / 5	TYR A 32 ASP A 77 GLU A 101 GLU A 177	None	1.48A	3dh0B-3g6iA: undetectable	3dh0B-3g6iA: 23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G4L_A_ROFA901_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	3g6i	PUTATIVE OUTER MEMBRANE PROTEIN, PART OF CARBOHYDRATE BINDING COMPLEX (Bacteroides thetaiotaomicron)	3 / 3	ASP A 51 LEU A 49 GLN A 41	None	0.80A	3g4lA-3g6iA: undetectable	3g4lA-3g6iA: 18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_B_TFPB202_1 (PROTEIN S100-A4)	3g6i	PUTATIVE OUTER MEMBRANE PROTEIN, PART OF CARBOHYDRATE BINDING COMPLEX (Bacteroides thetaiotaomicron)	3 / 3	GLU A 145 LEU A 148 ASP A 149	None	0.28A	3ko0A-3g6iA: undetectable	3ko0A-3g6iA: 18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_S_TFPS202_2 (PROTEIN S100-A4)	3g6i	PUTATIVE OUTER MEMBRANE PROTEIN, PART OF CARBOHYDRATE BINDING COMPLEX (Bacteroides thetaiotaomicron)	3 / 3	GLU A 145 LEU A 148 ASP A 149	None	0.19A	3ko0T-3g6iA: undetectable	3ko0T-3g6iA: 18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L7I_B_SAMB501_0 (S-ADENOSYLMETHIONINE SYNTHASE)	3g6i	PUTATIVE OUTER MEMBRANE PROTEIN, PART OF CARBOHYDRATE BINDING COMPLEX (Bacteroides thetaiotaomicron)	4 / 8	HIS A 112 ASP A 105 LEU A 108 ILE A 72	None	1.08A	4l7iA-3g6iA: undetectable	4l7iA-3g6iA: 19.57

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2X2N_A_X2NA1480_1","LANOSTEROL 14-ALPHA-DEMETHYLASE","3g6i","PUTATIVE OUTER MEMBRANE PROTEIN, PART OF CARBOHYDRATE BINDING COMPLEX","Bacteroides thetaiotaomicron",5,"TYR A  66;PRO A 116;ALA A 117;ALA A 176;ALA A 173","None","1.15A","2x2nA-3g6iA:undetectable","2x2nA-3g6iA:18.26"],["2X2N_B_X2NB1479_1","LANOSTEROL 14-ALPHA-DEMETHYLASE","3g6i","PUTATIVE OUTER MEMBRANE PROTEIN, PART OF CARBOHYDRATE BINDING COMPLEX","Bacteroides thetaiotaomicron",6,"PHE A 115;TYR A  66;PRO A 116;ALA A 117;ALA A 176;ALA A 173","None","1.39A","2x2nB-3g6iA:undetectable","2x2nB-3g6iA:18.26"],["2X2N_C_X2NC1479_1","LANOSTEROL 14-ALPHA-DEMETHYLASE","3g6i","PUTATIVE OUTER MEMBRANE PROTEIN, PART OF CARBOHYDRATE BINDING COMPLEX","Bacteroides thetaiotaomicron",5,"PHE A 115;TYR A  66;PRO A 116;ALA A 176;ALA A 173","None","1.27A","2x2nC-3g6iA:undetectable","2x2nC-3g6iA:18.26"],["3DH0_B_SAMB300_1","SAM DEPENDENT METHYLTRANSFERASE","3g6i","PUTATIVE OUTER MEMBRANE PROTEIN, PART OF CARBOHYDRATE BINDING COMPLEX","Bacteroides thetaiotaomicron",4,"TYR A  32;ASP A  77;GLU A 101;GLU A 177","None","1.48A","3dh0B-3g6iA:undetectable","3dh0B-3g6iA:23.38"],["3G4L_A_ROFA901_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D","3g6i","PUTATIVE OUTER MEMBRANE PROTEIN, PART OF CARBOHYDRATE BINDING COMPLEX","Bacteroides thetaiotaomicron",3,"ASP A  51;LEU A  49;GLN A  41","None","0.80A","3g4lA-3g6iA:undetectable","3g4lA-3g6iA:18.65"],["3KO0_B_TFPB202_1","PROTEIN S100-A4;PROTEIN S100-A4","3g6i","PUTATIVE OUTER MEMBRANE PROTEIN, PART OF CARBOHYDRATE BINDING COMPLEX","Bacteroides thetaiotaomicron",3,"GLU A 145;LEU A 148;ASP A 149","None","0.28A","3ko0A-3g6iA:undetectable","3ko0A-3g6iA:18.32"],["3KO0_S_TFPS202_2","PROTEIN S100-A4;PROTEIN S100-A4","3g6i","PUTATIVE OUTER MEMBRANE PROTEIN, PART OF CARBOHYDRATE BINDING COMPLEX","Bacteroides thetaiotaomicron",3,"GLU A 145;LEU A 148;ASP A 149","None","0.19A","3ko0T-3g6iA:undetectable","3ko0T-3g6iA:18.32"],["4L7I_B_SAMB501_0","S-ADENOSYLMETHIONINE SYNTHASE","3g6i","PUTATIVE OUTER MEMBRANE PROTEIN, PART OF CARBOHYDRATE BINDING COMPLEX","Bacteroides thetaiotaomicron",4,"HIS A 112;ASP A 105;LEU A 108;ILE A  72","None","1.08A","4l7iA-3g6iA:undetectable","4l7iA-3g6iA:19.57"]]