SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g6n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KEC_B_HAEB271_1 (COLLAGENASE 3)	3g6n	PEPTIDE DEFORMYLASE (Enterococcus faecium)	3 / 3	HIS A 157 GLU A 158 HIS A 161	FE A 188 (-3.4A) FE A 188 ( 4.8A) FE A 188 (-3.5A)	0.18A	3kecB-3g6nA: undetectable	3kecB-3g6nA: 20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W1W_A_CHDA1503_0 (FERROCHELATASE, MITOCHONDRIAL)	3g6n	PEPTIDE DEFORMYLASE (Enterococcus faecium)	4 / 8	ILE A 153 ARG A 127 VAL A 75 GLY A 60	None	0.90A	3w1wA-3g6nA: undetectable	3w1wA-3g6nA: 20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7B_B_HAEB1270_1 (COLLAGENASE 3)	3g6n	PEPTIDE DEFORMYLASE (Enterococcus faecium)	4 / 5	LEU A 41 HIS A 157 GLU A 158 HIS A 161	None FE A 188 (-3.4A) FE A 188 ( 4.8A) FE A 188 (-3.5A)	0.88A	4a7bB-3g6nA: undetectable	4a7bB-3g6nA: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5P9I_A_1E8A701_2 (TYROSINE-PROTEIN KINASE BTK)	3g6n	PEPTIDE DEFORMYLASE (Enterococcus faecium)	4 / 5	LEU A 108 TYR A 150 CYH A 114 ASP A 160	None None FE A 188 (-2.3A) None	1.18A	5p9iA-3g6nA: undetectable	5p9iA-3g6nA: 21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE8_C_08JC602_1 (CYTOCHROME P450 3A4)	3g6n	PEPTIDE DEFORMYLASE (Enterococcus faecium)	4 / 7	ARG A 71 ALA A 62 ILE A 68 LEU A 33	None	0.96A	5te8C-3g6nA: undetectable	5te8C-3g6nA: 17.23

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3KEC_B_HAEB271_1","COLLAGENASE 3","3g6n","PEPTIDE DEFORMYLASE","Enterococcus faecium",3,"HIS A 157;GLU A 158;HIS A 161"," FE A 188 (-3.4A); FE A 188 ( 4.8A); FE A 188 (-3.5A)","0.18A","3kecB-3g6nA:undetectable","3kecB-3g6nA:20.94"],["3W1W_A_CHDA1503_0","FERROCHELATASE, MITOCHONDRIAL","3g6n","PEPTIDE DEFORMYLASE","Enterococcus faecium",4,"ILE A 153;ARG A 127;VAL A  75;GLY A  60","None","0.90A","3w1wA-3g6nA:undetectable","3w1wA-3g6nA:20.49"],["4A7B_B_HAEB1270_1","COLLAGENASE 3","3g6n","PEPTIDE DEFORMYLASE","Enterococcus faecium",4,"LEU A  41;HIS A 157;GLU A 158;HIS A 161","None; FE A 188 (-3.4A); FE A 188 ( 4.8A); FE A 188 (-3.5A)","0.88A","4a7bB-3g6nA:undetectable","4a7bB-3g6nA:20.73"],["5P9I_A_1E8A701_2","TYROSINE-PROTEIN KINASE BTK","3g6n","PEPTIDE DEFORMYLASE","Enterococcus faecium",4,"LEU A 108;TYR A 150;CYH A 114;ASP A 160","None;None; FE A 188 (-2.3A);None","1.18A","5p9iA-3g6nA:undetectable","5p9iA-3g6nA:21.98"],["5TE8_C_08JC602_1","CYTOCHROME P450 3A4","3g6n","PEPTIDE DEFORMYLASE","Enterococcus faecium",4,"ARG A  71;ALA A  62;ILE A  68;LEU A  33","None","0.96A","5te8C-3g6nA:undetectable","5te8C-3g6nA:17.23"]]