SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g6s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 3g6s PUTATIVE
ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
FAMILY PROTEIN
(Bacteroides
vulgatus) 		3 / 3 PHE A 132
VAL A   4
TRP A   6
 None
 0.90A 2ccbA-3g6sA:
undetectable		 2ccbA-3g6sA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 3g6s PUTATIVE
ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
FAMILY PROTEIN
(Bacteroides
vulgatus) 		4 / 8 ILE A 154
ASN A 136
VAL A 135
ALA A 167
 None
 0.70A 2nniA-3g6sA:
undetectable		 2nniA-3g6sA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 3g6s PUTATIVE
ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
FAMILY PROTEIN
(Bacteroides
vulgatus) 		3 / 3 PHE A 132
VAL A   4
TRP A   6
 None
 0.89A 2vx9A-3g6sA:
undetectable		 2vx9A-3g6sA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3g6s PUTATIVE
ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
FAMILY PROTEIN
(Bacteroides
vulgatus) 		4 / 5 VAL A 228
PHE A 173
ILE A 185
PHE A 139
 None
 1.09A 3owxB-3g6sA:
undetectable		 3owxB-3g6sA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3g6s PUTATIVE
ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
FAMILY PROTEIN
(Bacteroides
vulgatus) 		5 / 12 GLN A  45
GLY A 171
ILE A  65
ALA A 134
ALA A 121
 None
 1.02A 3sudC-3g6sA:
undetectable		 3sudC-3g6sA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3g6s PUTATIVE
ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
FAMILY PROTEIN
(Bacteroides
vulgatus) 		5 / 12 GLN A  45
GLY A 171
ILE A  65
ALA A 134
ALA A 121
 None
 1.02A 3sueA-3g6sA:
undetectable		 3sueA-3g6sA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3g6s PUTATIVE
ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
FAMILY PROTEIN
(Bacteroides
vulgatus) 		3 / 3 TYR A  13
ARG A  69
HIS A 138
 None
 1.20A 4fubA-3g6sA:
undetectable		 4fubA-3g6sA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_1
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 3g6s PUTATIVE
ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
FAMILY PROTEIN
(Bacteroides
vulgatus) 		5 / 12 GLN A  45
THR A 137
ILE A 223
ASN A 174
HIS A 251
 None
 1.29A 4s0vA-3g6sA:
undetectable		 4s0vA-3g6sA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJL_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3g6s PUTATIVE
ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
FAMILY PROTEIN
(Bacteroides
vulgatus) 		5 / 12 PHE A  33
GLU A 242
LEU A 255
THR A 203
GLY A 204
 None
 1.48A 4zjlA-3g6sA:
undetectable		 4zjlA-3g6sA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 3g6s PUTATIVE
ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
FAMILY PROTEIN
(Bacteroides
vulgatus) 		3 / 3 ASP A 172
GLU A  77
SER A 179
 None
 0.80A 5bw4B-3g6sA:
undetectable		 5bw4B-3g6sA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 3g6s PUTATIVE
ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
FAMILY PROTEIN
(Bacteroides
vulgatus) 		5 / 12 HIS A 138
ASP A 172
ASN A 174
ILE A 223
HIS A 251
 None
 0.33A 5dv4A-3g6sA:
27.3		 5dv4A-3g6sA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 3g6s PUTATIVE
ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
FAMILY PROTEIN
(Bacteroides
vulgatus) 		5 / 11 PHE A   9
GLY A  43
ILE A  34
VAL A  30
PRO A 253
 None
 1.19A 5hjiA-3g6sA:
undetectable		 5hjiA-3g6sA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 3g6s PUTATIVE
ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
FAMILY PROTEIN
(Bacteroides
vulgatus) 		3 / 3 TYR A  88
ASP A  86
ASP A  40
 None
 0.84A 5x6yA-3g6sA:
2.6		 5x6yA-3g6sA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 3g6s PUTATIVE
ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
FAMILY PROTEIN
(Bacteroides
vulgatus) 		4 / 7 VAL A 162
PRO A  80
PHE A 123
LEU A  81
 None
 0.70A 6aycA-3g6sA:
undetectable		 6aycA-3g6sA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 3g6s PUTATIVE
ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
FAMILY PROTEIN
(Bacteroides
vulgatus) 		5 / 12 GLN A  45
GLY A 171
ILE A  65
ALA A 134
ALA A 121
 None
 0.97A 6c2mD-3g6sA:
undetectable		 6c2mD-3g6sA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_D_EY4D500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3g6s PUTATIVE
ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
FAMILY PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ILE A 239
VAL A 202
ALA A 199
THR A 198
 None
 0.99A 6cduC-3g6sA:
undetectable
6cduD-3g6sA:
undetectable		 6cduC-3g6sA:
20.47
6cduD-3g6sA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3g6s PUTATIVE
ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
FAMILY PROTEIN
(Bacteroides
vulgatus) 		4 / 8 ASP A 250
HIS A 141
HIS A 210
ASP A 172
 None
 1.18A 6mn4C-3g6sA:
undetectable		 6mn4C-3g6sA:
22.89