SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g7g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 3g7g UPF0311 PROTEIN
CA_C3321
(Clostridium
acetobutylicum) 		3 / 3 ARG A  76
SER A  74
TYR A  88
 None
 0.90A 2q2hA-3g7gA:
undetectable
2q2hB-3g7gA:
undetectable		 2q2hA-3g7gA:
20.99
2q2hB-3g7gA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 3g7g UPF0311 PROTEIN
CA_C3321
(Clostridium
acetobutylicum) 		4 / 6 TYR A  88
ALA A  78
ALA A  75
ASN A  92
 None
 0.87A 3b6hA-3g7gA:
undetectable		 3b6hA-3g7gA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 3g7g UPF0311 PROTEIN
CA_C3321
(Clostridium
acetobutylicum) 		4 / 7 VAL A  55
GLY A  59
ILE A  60
VAL A 150
 None
 0.82A 3ufnB-3g7gA:
undetectable		 3ufnB-3g7gA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)		 3g7g UPF0311 PROTEIN
CA_C3321
(Clostridium
acetobutylicum) 		5 / 7 ALA A  78
ALA A  75
ILE A  60
GLY A  59
ILE A  41
 None
 0.88A 4eatA-3g7gA:
undetectable		 4eatA-3g7gA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 3g7g UPF0311 PROTEIN
CA_C3321
(Clostridium
acetobutylicum) 		5 / 9 ALA A  78
ALA A  75
ILE A  60
GLY A  59
ILE A  41
 None
 0.91A 4eatB-3g7gA:
undetectable		 4eatB-3g7gA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 3g7g UPF0311 PROTEIN
CA_C3321
(Clostridium
acetobutylicum) 		4 / 5 TYR A  88
ILE A  87
ASN A  91
ILE A  79
 None
 0.91A 4jtpA-3g7gA:
undetectable		 4jtpA-3g7gA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 3g7g UPF0311 PROTEIN
CA_C3321
(Clostridium
acetobutylicum) 		4 / 8 ASP A  82
TYR A 131
ASP A  83
ILE A  79
 None
 0.87A 4xjeA-3g7gA:
undetectable		 4xjeA-3g7gA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 3g7g UPF0311 PROTEIN
CA_C3321
(Clostridium
acetobutylicum) 		4 / 8 ASP A  82
TYR A 131
ASP A  83
ILE A  79
 None
 0.94A 5cfsA-3g7gA:
undetectable		 5cfsA-3g7gA:
24.21