SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g7n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 3g7n LIPASE
(Penicillium
expansum) 		4 / 6 ASN A 185
HIS A 131
ALA A 243
GLY A 246
 None
 1.09A 1c8lA-3g7nA:
2.6		 1c8lA-3g7nA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 6 ASN A 185
HIS A 131
ALA A 243
GLY A 246
 None
 1.08A 1gfzA-3g7nA:
2.8		 1gfzA-3g7nA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3g7n LIPASE
(Penicillium
expansum) 		5 / 9 GLY A 183
ALA A  14
GLY A 134
THR A 138
SER A  18
 None
 1.20A 1gtfR-3g7nA:
undetectable
1gtfS-3g7nA:
undetectable		 1gtfR-3g7nA:
17.27
1gtfS-3g7nA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 5 GLY A 246
SER A 216
THR A 217
PHE A   8
 None
 1.34A 1icrA-3g7nA:
undetectable
1icrB-3g7nA:
undetectable		 1icrA-3g7nA:
20.00
1icrB-3g7nA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 5 GLY A 246
SER A 216
THR A 217
PHE A   8
 None
 1.40A 1icvA-3g7nA:
undetectable
1icvB-3g7nA:
undetectable		 1icvA-3g7nA:
20.00
1icvB-3g7nA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 5 GLY A 246
SER A 216
THR A 217
PHE A   8
 None
 1.32A 1icvC-3g7nA:
undetectable
1icvD-3g7nA:
undetectable		 1icvC-3g7nA:
20.00
1icvD-3g7nA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 6 ASN A 185
HIS A 131
ALA A 243
GLY A 246
 None
 1.03A 1l5qA-3g7nA:
undetectable		 1l5qA-3g7nA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 6 ASN A 185
HIS A 131
ALA A 243
GLY A 246
 None
 1.04A 1l5qB-3g7nA:
undetectable		 1l5qB-3g7nA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 6 ASN A 185
HIS A 131
ALA A 243
GLY A 246
 None
 0.99A 1l7xA-3g7nA:
undetectable		 1l7xA-3g7nA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 6 ASN A 185
HIS A 131
ALA A 243
GLY A 246
 None
 1.01A 1l7xB-3g7nA:
undetectable		 1l7xB-3g7nA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 3g7n LIPASE
(Penicillium
expansum) 		5 / 11 GLY A  64
SER A  65
VAL A 237
VAL A 190
HIS A 241
 None
SO4  A 259 (-3.5A)
SO4  A 259 (-4.9A)
None
SO4  A 259 ( 4.6A)
 0.94A 1ukbA-3g7nA:
4.9		 1ukbA-3g7nA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 6 ALA A 116
GLU A 113
TYR A 121
ILE A  58
 None
PEG  A 266 (-3.1A)
None
None
 0.97A 1xvaA-3g7nA:
undetectable
1xvaB-3g7nA:
undetectable		 1xvaA-3g7nA:
23.34
1xvaB-3g7nA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3g7n LIPASE
(Penicillium
expansum) 		5 / 9 TYR A 194
PHE A 162
PRO A 102
LEU A 137
ALA A 136
 None
 1.27A 2vcvE-3g7nA:
undetectable		 2vcvE-3g7nA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3g7n LIPASE
(Penicillium
expansum) 		5 / 9 TYR A 194
PHE A 162
PRO A 102
LEU A 137
ALA A 136
 None
 1.25A 2vcvH-3g7nA:
undetectable		 2vcvH-3g7nA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 6 ASN A 185
HIS A 131
ALA A 243
GLY A 246
 None
 1.04A 3dd1A-3g7nA:
undetectable		 3dd1A-3g7nA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 6 ASN A 185
HIS A 131
ALA A 243
GLY A 246
 None
 1.05A 3dd1B-3g7nA:
undetectable		 3dd1B-3g7nA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 6 ASN A 185
HIS A 131
ALA A 243
GLY A 246
 None
 1.06A 3ddsA-3g7nA:
undetectable		 3ddsA-3g7nA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 6 ASN A 185
HIS A 131
ALA A 243
GLY A 246
 None
 1.04A 3ddsB-3g7nA:
undetectable		 3ddsB-3g7nA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 6 ASN A 185
HIS A 131
ALA A 243
GLY A 246
 None
 1.03A 3ddwA-3g7nA:
undetectable		 3ddwA-3g7nA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 6 ASN A 185
HIS A 131
ALA A 243
GLY A 246
 None
 1.03A 3ddwB-3g7nA:
undetectable		 3ddwB-3g7nA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 3g7n LIPASE
(Penicillium
expansum) 		6 / 12 GLY A  50
ALA A  59
VAL A 129
GLY A  47
ILE A  38
THR A 138
 None
 1.35A 3el5B-3g7nA:
undetectable		 3el5B-3g7nA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 3g7n LIPASE
(Penicillium
expansum) 		5 / 12 HIS A 241
ASP A 188
PHE A 162
ALA A 161
ALA A 136
 SO4  A 259 ( 4.6A)
None
None
None
None
 1.11A 3keeA-3g7nA:
undetectable		 3keeA-3g7nA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		 3g7n LIPASE
(Penicillium
expansum) 		5 / 12 HIS A 241
ASP A 188
PHE A 162
ALA A 161
ALA A 136
 SO4  A 259 ( 4.6A)
None
None
None
None
 1.12A 3keeD-3g7nA:
undetectable		 3keeD-3g7nA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_A_ACTA601_0
(CHOLINE OXIDASE)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 5 ILE A 111
HIS A 107
VAL A  87
ASN A 148
 None
 1.48A 3nneA-3g7nA:
0.9		 3nneA-3g7nA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3g7n LIPASE
(Penicillium
expansum) 		6 / 12 HIS A 241
VAL A 186
ASP A 188
PHE A 162
ALA A 161
ALA A 136
 SO4  A 259 ( 4.6A)
None
None
None
None
None
 1.20A 3sudD-3g7nA:
undetectable		 3sudD-3g7nA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3g7n LIPASE
(Penicillium
expansum) 		6 / 12 HIS A 241
VAL A 186
ASP A 188
PHE A 162
ALA A 161
ALA A 136
 SO4  A 259 ( 4.6A)
None
None
None
None
None
 1.18A 3sueC-3g7nA:
undetectable		 3sueC-3g7nA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3g7n LIPASE
(Penicillium
expansum) 		6 / 12 HIS A 241
VAL A 186
ASP A 188
PHE A 162
ALA A 161
ALA A 136
 SO4  A 259 ( 4.6A)
None
None
None
None
None
 1.17A 3sufD-3g7nA:
undetectable		 3sufD-3g7nA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 8 TYR A 204
ILE A 140
VAL A  99
GLY A 135
 None
 0.84A 4eq4B-3g7nA:
undetectable		 4eq4B-3g7nA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 7 GLY A 173
ASP A 171
GLY A 165
ILE A 164
 None
 0.66A 5kqyB-3g7nA:
undetectable		 5kqyB-3g7nA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 8 SER A 229
ARG A 224
ASN A 232
ASP A 188
 None
 1.29A 5vuoB-3g7nA:
undetectable		 5vuoB-3g7nA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 8 GLY A  64
GLY A 134
LEU A 137
ALA A 136
 None
 0.71A 5vw5A-3g7nA:
undetectable		 5vw5A-3g7nA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_D_HFGD1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3g7n LIPASE
(Penicillium
expansum) 		5 / 12 LEU A 133
VAL A  99
PRO A 102
THR A  43
ARG A 101
 None
 1.23A 5xipD-3g7nA:
undetectable		 5xipD-3g7nA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3g7n LIPASE
(Penicillium
expansum) 		4 / 8 SER A 229
ARG A 224
ASN A 232
ASP A 188
 None
 1.29A 6auuB-3g7nA:
undetectable		 6auuB-3g7nA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 3g7n LIPASE
(Penicillium
expansum) 		6 / 12 HIS A 241
VAL A 186
ASP A 188
PHE A 162
ALA A 161
ALA A 136
 SO4  A 259 ( 4.6A)
None
None
None
None
None
 1.18A 6c2mC-3g7nA:
undetectable		 6c2mC-3g7nA:
15.48