SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g7q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 3g7q VALINE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 8 TYR A  49
PHE A  50
MET A  46
ARG A 300
 None
 1.29A 1ea1A-3g7qA:
undetectable		 1ea1A-3g7qA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 3g7q VALINE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 12 LEU A 215
ILE A 261
ASN A 240
ILE A 213
ALA A 208
 None
 1.13A 2ejtA-3g7qA:
undetectable		 2ejtA-3g7qA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 3g7q VALINE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 5 LEU A 341
ILE A 398
ILE A 320
ALA A 319
 None
 0.66A 2i2zA-3g7qA:
undetectable		 2i2zA-3g7qA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 3g7q VALINE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 4 LEU A 341
ILE A 398
ILE A 320
ALA A 319
 None
 0.83A 2i30A-3g7qA:
undetectable		 2i30A-3g7qA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_1
(PROTEASE)		 3g7q VALINE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 12 LEU A 130
ALA A 208
ASP A 205
ILE A 241
ILE A 183
 None
 1.25A 2o4lA-3g7qA:
undetectable		 2o4lA-3g7qA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 3g7q VALINE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 12 LEU A 359
GLU A 353
MET A 387
LEU A 348
ILE A 350
 None
 1.29A 2ydoA-3g7qA:
undetectable		 2ydoA-3g7qA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 3g7q VALINE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 5 PRO A 395
ILE A 398
PRO A 393
TYR A 391
 None
 1.23A 3d9lA-3g7qA:
undetectable
3d9lY-3g7qA:
undetectable		 3d9lA-3g7qA:
15.38
3d9lY-3g7qA:
3.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3g7q VALINE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 12 GLY A 222
ALA A 220
SER A 186
ALA A 233
ILE A 229
 None
 1.17A 3id6C-3g7qA:
undetectable		 3id6C-3g7qA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 3g7q VALINE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 7 TRP A 380
PRO A 155
GLY A 375
PRO A 374
 None
 1.31A 3ucbB-3g7qA:
undetectable		 3ucbB-3g7qA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 3g7q VALINE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		3 / 3 ARG A 358
ARG A 362
ILE A 350
 None
 0.89A 4b7qA-3g7qA:
undetectable		 4b7qA-3g7qA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 3g7q VALINE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		3 / 3 ARG A 358
ARG A 362
ILE A 350
 None
 0.91A 4b7qC-3g7qA:
undetectable		 4b7qC-3g7qA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 3g7q VALINE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 5 LEU A 299
LEU A  86
MET A 245
TRP A  93
 None
 1.30A 4do3A-3g7qA:
undetectable		 4do3A-3g7qA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 3g7q VALINE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 8 LEU A  91
LEU A 243
ASN A 219
ILE A 241
 None
 0.89A 5mzjA-3g7qA:
undetectable		 5mzjA-3g7qA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_2
(CYTOCHROME P450 3A4)		 3g7q VALINE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 6 PHE A 114
PHE A 117
ILE A 270
THR A 266
 None
 1.11A 5vceA-3g7qA:
undetectable		 5vceA-3g7qA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 3g7q VALINE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 12 LEU A 376
GLY A 375
SER A 186
ILE A 138
ASP A 142
 None
 1.29A 6bxnB-3g7qA:
undetectable		 6bxnB-3g7qA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3g7q VALINE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 11 PRO A 281
SER A 246
PRO A 286
SER A 255
LEU A  83
 None
 1.40A 6dlzA-3g7qA:
3.1
6dlzD-3g7qA:
3.0		 6dlzA-3g7qA:
10.55
6dlzD-3g7qA:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3g7q VALINE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 11 PRO A 281
SER A 246
PRO A 286
SER A 255
LEU A  83
 None
 1.40A 6dm1A-3g7qA:
2.4
6dm1D-3g7qA:
3.0		 6dm1A-3g7qA:
10.55
6dm1D-3g7qA:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3g7q VALINE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		3 / 3 LEU A 298
ASN A 219
LEU A  91
 None
 0.55A 6exiD-3g7qA:
undetectable		 6exiD-3g7qA:
13.67