SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g7s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 3g7s LONG-CHAIN-FATTY-ACI
D--COA LIGASE
(FADD-1)
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 239
ASN A 238
LEU A 236
GLY A 235
ALA A 204
 None
 1.12A 1gs4A-3g7sA:
undetectable		 1gs4A-3g7sA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_B_ADNB2002_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3g7s LONG-CHAIN-FATTY-ACI
D--COA LIGASE
(FADD-1)
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 435
TRP A 333
PRO A 340
ALA A 338
 None
 1.23A 2ejfB-3g7sA:
undetectable		 2ejfB-3g7sA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3g7s LONG-CHAIN-FATTY-ACI
D--COA LIGASE
(FADD-1)
(Archaeoglobus
fulgidus) 		4 / 7 SER A  38
SER A  85
VAL A 249
SER A  45
 None
 1.43A 2j9cA-3g7sA:
undetectable
2j9cB-3g7sA:
undetectable
2j9cC-3g7sA:
undetectable		 2j9cA-3g7sA:
13.66
2j9cB-3g7sA:
13.66
2j9cC-3g7sA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 3g7s LONG-CHAIN-FATTY-ACI
D--COA LIGASE
(FADD-1)
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 239
ASN A 238
LEU A 236
GLY A 235
ALA A 204
 None
 1.16A 2oz7A-3g7sA:
undetectable		 2oz7A-3g7sA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PK4_A_ACAA100_1
(HUMAN PLASMINOGEN
KRINGLE 4)		 3g7s LONG-CHAIN-FATTY-ACI
D--COA LIGASE
(FADD-1)
(Archaeoglobus
fulgidus) 		4 / 7 LYS A 366
TRP A 407
PHE A 415
ARG A 413
 None
 1.25A 2pk4A-3g7sA:
undetectable		 2pk4A-3g7sA:
7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X08_A_ASCA1253_0
(CYTOCHROME C
PEROXIDASE,
MITOCHONDRIAL)		 3g7s LONG-CHAIN-FATTY-ACI
D--COA LIGASE
(FADD-1)
(Archaeoglobus
fulgidus) 		5 / 9 ALA A  20
ASP A  21
ILE A  17
PRO A 176
VAL A 174
 None
 1.24A 2x08A-3g7sA:
0.0		 2x08A-3g7sA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)		 3g7s LONG-CHAIN-FATTY-ACI
D--COA LIGASE
(FADD-1)
(Archaeoglobus
fulgidus) 		4 / 6 LEU A 284
GLU A 285
LYS A 313
LEU A 317
 None
 0.78A 3h5gA-3g7sA:
undetectable
3h5gC-3g7sA:
undetectable		 3h5gA-3g7sA:
4.92
3h5gC-3g7sA:
4.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3g7s LONG-CHAIN-FATTY-ACI
D--COA LIGASE
(FADD-1)
(Archaeoglobus
fulgidus) 		5 / 12 ILE A  36
LEU A  95
PHE A  47
ILE A  82
VAL A 127
 None
 0.93A 3w67B-3g7sA:
undetectable		 3w67B-3g7sA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 3g7s LONG-CHAIN-FATTY-ACI
D--COA LIGASE
(FADD-1)
(Archaeoglobus
fulgidus) 		3 / 3 LEU A 284
GLU A 285
SER A 287
 None
 0.66A 4ccqA-3g7sA:
2.5		 4ccqA-3g7sA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 3g7s LONG-CHAIN-FATTY-ACI
D--COA LIGASE
(FADD-1)
(Archaeoglobus
fulgidus) 		4 / 5 THR A 125
GLY A  79
VAL A 103
PRO A 102
 None
 1.08A 4grkA-3g7sA:
0.7		 4grkA-3g7sA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3g7s LONG-CHAIN-FATTY-ACI
D--COA LIGASE
(FADD-1)
(Archaeoglobus
fulgidus) 		5 / 12 ASN A  84
ALA A 232
GLY A 235
ILE A 332
GLY A 334
 None
 1.26A 4obwA-3g7sA:
undetectable		 4obwA-3g7sA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 3g7s LONG-CHAIN-FATTY-ACI
D--COA LIGASE
(FADD-1)
(Archaeoglobus
fulgidus) 		3 / 3 VAL A 241
ALA A  25
PHE A  30
 None
 0.82A 4olbA-3g7sA:
2.6		 4olbA-3g7sA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA305_0
(THAUMATIN-1)		 3g7s LONG-CHAIN-FATTY-ACI
D--COA LIGASE
(FADD-1)
(Archaeoglobus
fulgidus) 		4 / 5 LYS A 352
ILE A 424
PHE A 423
VAL A 378
 None
 1.15A 4tvtA-3g7sA:
0.0		 4tvtA-3g7sA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3g7s LONG-CHAIN-FATTY-ACI
D--COA LIGASE
(FADD-1)
(Archaeoglobus
fulgidus) 		3 / 3 VAL A 241
ALA A  25
PHE A  30
 None
 0.94A 4w5nA-3g7sA:
2.5		 4w5nA-3g7sA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3g7s LONG-CHAIN-FATTY-ACI
D--COA LIGASE
(FADD-1)
(Archaeoglobus
fulgidus) 		4 / 5 ALA A  20
TYR A  93
PRO A 102
PHE A 234
 None
 1.29A 4ze2A-3g7sA:
undetectable		 4ze2A-3g7sA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3g7s LONG-CHAIN-FATTY-ACI
D--COA LIGASE
(FADD-1)
(Archaeoglobus
fulgidus) 		5 / 12 ILE A 386
LEU A 365
GLY A 334
GLY A 187
PHE A 392
 None
 1.12A 5d4uB-3g7sA:
3.4		 5d4uB-3g7sA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 3g7s LONG-CHAIN-FATTY-ACI
D--COA LIGASE
(FADD-1)
(Archaeoglobus
fulgidus) 		5 / 12 VAL A 493
ASP A 494
GLU A 520
ALA A 461
LEU A 456
 None
 1.33A 5m54B-3g7sA:
undetectable		 5m54B-3g7sA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_B_NIOB401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3g7s LONG-CHAIN-FATTY-ACI
D--COA LIGASE
(FADD-1)
(Archaeoglobus
fulgidus) 		4 / 7 VAL A  78
VAL A 127
PHE A 149
ILE A  67
 None
 0.84A 5yf9B-3g7sA:
undetectable		 5yf9B-3g7sA:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3g7s LONG-CHAIN-FATTY-ACI
D--COA LIGASE
(FADD-1)
(Archaeoglobus
fulgidus) 		3 / 3 ASN A 135
VAL A 151
HIS A 129
 None
 0.87A 6a5yD-3g7sA:
undetectable		 6a5yD-3g7sA:
10.32