SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g7t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		5 / 9 VAL A 322
HIS A  27
ALA A 369
ILE A 367
THR A 315
 None
 1.28A 1gtnL-3g7tA:
undetectable
1gtnM-3g7tA:
0.7		 1gtnL-3g7tA:
12.00
1gtnM-3g7tA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_2
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION
CHIMERA OF IG
GAMMA-1 CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		4 / 5 TYR A 326
GLU A 362
PRO A 332
ASP A 360
 None
 1.21A 1i7zB-3g7tA:
4.4		 1i7zB-3g7tA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		4 / 7 ILE A 335
HIS A  27
GLU A  26
LEU A 321
 None
 1.08A 1j96B-3g7tA:
undetectable		 1j96B-3g7tA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		4 / 4 HIS A 282
GLU A  26
HIS A  27
HIS A 317
 None
 1.15A 1os2D-3g7tA:
undetectable		 1os2D-3g7tA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		4 / 4 HIS A 282
GLU A  26
HIS A  27
HIS A 317
 None
 1.24A 1uttA-3g7tA:
undetectable		 1uttA-3g7tA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		4 / 8 ALA A 117
ALA A 250
LYS A 248
LEU A 114
 None
 0.90A 2bxgA-3g7tA:
undetectable		 2bxgA-3g7tA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		4 / 4 HIS A 282
GLU A  26
HIS A  27
HIS A 317
 None
 1.17A 2hu6A-3g7tA:
undetectable		 2hu6A-3g7tA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		4 / 4 HIS A 282
GLU A  26
HIS A  27
HIS A 317
 None
 1.29A 2ozrE-3g7tA:
undetectable		 2ozrE-3g7tA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		4 / 4 VAL A  31
ARG A 286
ILE A 164
THR A  33
 None
 1.36A 3cl9A-3g7tA:
undetectable		 3cl9A-3g7tA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		3 / 3 LEU A 253
LEU A 237
ARG A 233
 None
 0.53A 3hcnB-3g7tA:
undetectable		 3hcnB-3g7tA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		4 / 4 HIS A 282
GLU A  26
HIS A  27
HIS A 317
 None
 1.20A 3lilA-3g7tA:
undetectable		 3lilA-3g7tA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		5 / 12 VAL A  31
SER A  29
ILE A 357
ILE A 367
LEU A 351
 None
 0.99A 3w67D-3g7tA:
undetectable		 3w67D-3g7tA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_B_HAEB1270_1
(COLLAGENASE 3)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		4 / 5 LEU A 351
HIS A 282
GLU A  26
HIS A  27
 None
 1.16A 4a7bB-3g7tA:
undetectable		 4a7bB-3g7tA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		3 / 3 GLU A  26
THR A 315
HIS A 317
 None
 0.80A 4q15A-3g7tA:
undetectable		 4q15A-3g7tA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		3 / 3 GLU A  26
THR A 315
HIS A 317
 None
 0.82A 4q15B-3g7tA:
undetectable		 4q15B-3g7tA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		5 / 5 ILE A  43
VAL A  23
ILE A   6
VAL A  31
THR A  33
 None
 1.25A 4xdtA-3g7tA:
undetectable		 4xdtA-3g7tA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_A_HFGA802_1
(PROLINE--TRNA LIGASE)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		4 / 4 THR A 353
GLU A  26
THR A 315
HIS A 317
 None
 1.28A 4ydqA-3g7tA:
undetectable		 4ydqA-3g7tA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		3 / 3 GLU A  26
THR A 315
HIS A 317
 None
 0.82A 4ydqB-3g7tA:
undetectable		 4ydqB-3g7tA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_1
(AMINOACYL-TRNA
SYNTHETASE)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		4 / 4 THR A 353
GLU A  26
THR A 315
HIS A 317
 None
 1.32A 5f9zA-3g7tA:
0.2		 5f9zA-3g7tA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_B_HFGB703_1
(AMINOACYL-TRNA
SYNTHETASE)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		4 / 4 THR A 353
GLU A  26
THR A 315
HIS A 317
 None
 1.33A 5f9zB-3g7tA:
undetectable		 5f9zB-3g7tA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		5 / 11 ILE A 270
ILE A 278
VAL A 130
VAL A 197
LEU A 191
 None
 1.13A 5jkwA-3g7tA:
undetectable		 5jkwA-3g7tA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		4 / 4 HIS A 282
GLU A  26
HIS A  27
HIS A 317
 None
 1.20A 5n5jA-3g7tA:
undetectable		 5n5jA-3g7tA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_B_HFGB802_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		5 / 12 PHE A 337
PRO A 356
THR A 353
GLU A  26
HIS A  27
 None
 1.33A 5xioB-3g7tA:
undetectable		 5xioB-3g7tA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_C_HFGC1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		5 / 12 PHE A 337
PRO A 356
THR A 353
GLU A  26
HIS A  27
 None
 1.29A 5xiqC-3g7tA:
undetectable		 5xiqC-3g7tA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_C_HFGC1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		5 / 12 PHE A 337
PRO A 356
THR A 353
GLU A  26
HIS A 282
 None
 1.49A 5xiqC-3g7tA:
undetectable		 5xiqC-3g7tA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3g7t ENVELOPE PROTEIN
(Dengue
virus) 		3 / 3 HIS A 317
HIS A  27
HIS A 282
 None
 0.76A 6giqa-3g7tA:
undetectable		 6giqa-3g7tA:
19.60